The large and complex gut microbiota in animals has profound effects on feed utilization metabolism. Currently, gastrointestinal diseases due to dysregulated are considered important factors that limit growth of the captive forest musk deer population. Compared with deer, wild have a wider feeding range no dietary limitations, their relatively natural state. However, reports compared between deer. To gain insight into composition under different food-source conditions, we employed...

Screen time has become an integral part of children's daily lives. Nevertheless, the developmental consequences screen exposure in young children remain unclear.To investigate trajectory from 6 to 72 months age and its association with development at a prospective birth cohort.Women Shanghai, China, who were 34 36 gestational weeks had expected delivery date between May 2012 July 2013 recruited for this cohort study. Their followed up 6, 9, 12, 18, 24, 36, 48, age. Children's was classified...

Diarrhea constitutes one of the most common diseases affecting survival captive musk deer and is usually caused by an imbalance in intestinal microbiota. Currently, research regarding structure function microbiota diarrheic lacking. Therefore, present study, high-throughput 16S-rRNA gene sequencing was used to analyze feces healthy (HMD) (n = 8) with mild (MMD) 8), severe 5) (SMD) diarrhea compare difference under various physiological conditions. The results showed that diversity HMD fecal...

Developmental language disorder (DLD) is a condition that significantly affects children's achievement but has been understudied. We aim to estimate the prevalence of DLD in Shanghai, compare co-occurrence difficulties between children with and those typical development (TD), investigate early risk factors for DLD.We estimated using data from population-based survey cluster random sampling design China. A subsample (aged 5-6 years) received an onsite evaluation, each child was categorized as...

Race-based discrimination is associated with negative mental health outcomes for Chinese international students. Host and ethnic social connectedness have been demonstrated to buffer the effects of on health. However, most studies thus far utilized cross-sectional designs. The current study was a longitudinal investigation race- language-based anxiety depression symptoms among 210 students studying in U.S. Participants were assessed during their first academic term at university (T1) 3...

Multiple genes have been associated with familial dilated cardiomyopathy (DCM). However, the role of genetic factors in sporadic DCM (SDCM) remains unclear. Therefore, we studied variations Chinese patients SDCM.Sixty-six unrelated (mean age 49.1±17.0 years; 71% male) diagnosed SDCM were enrolled. The clinical history and genomic DNA cohort collected examined. exons 24 closely (ABCC9, ACTC1, ACTN2, DES, LAMA4, LDB3, LMNA, MYBPC3, MYH6, MYH7, MYPN, PLN, PSEN1, PSEN2, RBM20, SCN5A, SGCD, TAZ,...

Background Experimental evidence shows postnatal exposure to anesthesia negatively affects brain development. The PDZ2 domain, mediating protein–protein interactions of the postsynaptic density-95 protein, serves as a molecular target for several inhaled anesthetics. authors hypothesized that early disruption domain has persistent effects on dendritic spines and cognitive function. Methods One-week-old mice were exposed 1.5% isoflurane 4 h or injected with 8 mg/kg active wild-type peptide...

Diet plays a crucial role in shaping the gut microbiota and overall health of animals. Traditionally, silkworms are fed fresh mulberry leaves, artificial diets do not support good health. The aim this study was to explore relationship between dietary transition from leaves effects on physiological changes as model organism. With diversity silkworm increased, proportion Enterococcus Weissella, dominant bacterial species reared diets, decreased, whereas abundance Achromobacter Rhodococcus...

Study objectives To characterize sleep disturbances and patterns in children with Tic disorder (TD), explore their association TD severity types. Methods A case-control study was conducted 271 recruited from a clinical setting non-TD primary school, matched by age (mean = 8.47 years, SD 1.53 years) gender (15.1% female). The Children's Sleep Habits Questionnaire (CSHQ) used to assess disturbances. types were assessed the Yale Global Severity Scale (YGTSS). Results scored higher on CSHQ total...

Forest musk deer (Moschus berezovskii; FMD) are both economically valuable and highly endangered. A problem for FMD captive breeding programs has been the susceptibility of to abscesses. To investigate mechanisms abscess development in FMD, blood transcriptomes three purulent healthy individuals were generated. total ~39.68 Gb bases generated using Illumina HiSeq 4000 sequencing technology 77,752 unigenes identified after assembling. All annotated, with 63,531 (81.71%) mapping at least one...

Early onset of depression predicts unfavorable psychosocial and health outcomes, often co-occurs for children their parents, yet family profiles trajectories are not fully examined. This population-based longitudinal prospective cohort study included 2,111 families drawn from the Chinese Family Panel Study (CFPS) with biannual assessments 2010 to 2018. Group-based multitrajectory modeling was used identify children, fathers, mothers. Six distinct symptoms were identified. Based upon findings...

In the context of coronavirus disease-2019 (COVID-19) pandemic, mental health problems parents and children have become a public issue. Herein, we explored association between parental well-being index child during pandemic mediating role harsh parenting sleep disturbances. An online survey was conducted among 16,398 aged 3-6 years (48.1% girls, Mage = 4.69 years, SDage 0.75 years) from March 15 to 29, 2020. Child (Strengths Difficulties Questionnaire, SDQ), (Children's Sleep Habits CSHQ),...

An estimated one million international students are enrolled in U.S. universities. However, little was known about the landscape of their mental health and help-seeking behaviors. Drawing from a large national university student sample (N = 228,421, 8.49% non-U.S. citizen) Healthy Minds Study, data indicated rates major depressive disorder, generalized anxiety eating non-suicidal self-injury, suicidal ideation were 27.4%, 20.0%, 26.4%, 17.2%, 8.8% respectively among students, with high...

Temperature is an important environmental factor affecting the growth and development of silkworm (Bombyx mori). To analyze effect intestinal microbes on in response to a high-temperature environment, this study used combination high throughput sequencing biochemical assays detect treated with temperature for 72 h. The results show that affects there are sex differences, specifically, females were more sensitive. changes metabolism transport ability tissues under related microbes. High...

To investigate trajectories of early childhood sleep in the first three years and association with maternal depressive symptoms. Data was from 243 Chinese mother-child dyads. Children's duration night-waking were assessed using Brief Infant Sleep Questionnaire (BISQ) at 42 days, 3, 6, 9, 12, 18, 24, 36 months postpartum. The Center for Epidemiological Survey-Depression Scale (CES-D), Edinburgh Postnatal Depression (EPDS), Profile Mood States (POMS) used to assess symptoms late pregnancy,...

While recent works suggested that overweight/obesity may impair executive function (EF), the overweight/obesity-EF relationship has not been well studied in adolescents. Furthermore, no research investigated adolescent EF impairments across weight spectrum (e.g., underweight or thinness, normal, overweight/obesity), especially those with condition, moderating effect of negative emotions weight-EF association being limitedly investigated. We aimed to determine whether overall and abdominal...

Abstract Child self-regulation (SR), a key indicator for later optimal developmental outcomes, may be compromised in the presence of parental mental disorders, especially those characterized by affective dysregulation. However, positive behaviors have been shown to buffer against such negative effects, during infancy when SR shows great plasticity environmental inputs. The current study investigated effect maternal and paternal lifetime internalizing disorders on trajectory infant from 3 24...