Guang Wang

ORCID: 0000-0001-7618-5652
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Insect Utilization and Effects
  • Silkworms and Sericulture Research
  • Invertebrate Immune Response Mechanisms
  • Silk-based biomaterials and applications
  • Neurobiology and Insect Physiology Research
  • Immune Cell Function and Interaction
  • Insect-Plant Interactions and Control
  • Mesenchymal stem cell research
  • Adipokines, Inflammation, and Metabolic Diseases
  • Viral Infectious Diseases and Gene Expression in Insects
  • Erythrocyte Function and Pathophysiology
  • Reproductive System and Pregnancy
  • FOXO transcription factor regulation
  • Signaling Pathways in Disease
  • Asthma and respiratory diseases
  • Muscle Physiology and Disorders
  • Plant Parasitism and Resistance
  • Cancer Immunotherapy and Biomarkers
  • Animal and Plant Science Education
  • Bone Metabolism and Diseases
  • Inflammation biomarkers and pathways
  • Cardiac tumors and thrombi
  • Ocular Surface and Contact Lens
  • Extracellular vesicles in disease
  • Environmental Sustainability in Business

Soochow University
2021-2024

Beijing Institute of Technology
2023

University of South China
2021

Jinan University
2016-2020

Shandong Agricultural University
2011

Kanazawa University
2009

Air Force Medical University
2006

Tufts University
2003

Abstract Bombyx mori silk is a super-long natural protein fiber with unique structure and excellent performance. Innovative structures high performance are in great demand, thus resulting an industrial bottleneck. Herein, the outer layer sericin SER3 ectopically expressed posterior gland (PSG) silkworms via piggyBac -mediated transgenic approach, then secreted into inner fibroin layer, generating microsomes dispersed fibrils. The water-soluble by PSG causes P25’s detachment from unit of...

10.1038/s41467-022-34128-5 article EN cc-by Nature Communications 2022-10-22

Chinese mitten crabs ( Eriocheir sinensis ) are traditionally fed iced trash fish, but the industry is facing problems such as low breeding safety. Black soldier fly Hermetia illucens an alternative protein source in animal diets, including diets for aquatic animals, due to its high nutritional value. However, studies on effects of black flavor characteristics animals still limited. In present study, we investigated complete replacement fish with larvae during fattening period crab molecule...

10.3389/fmars.2022.1089421 article EN cc-by Frontiers in Marine Science 2023-01-09

Mesenchymal stem cells (MSCs) are a promising cell resource for the treatment of ischemic diseases, partially through paracrine effects. One major obstacles MSC is poor survival rate and low efficiency transplanted due to or inflammatory environments. Gremlin1 (GREM1), regulator growth, differentiation development, has been identified as novel proangiogenic factor. However, role mechanism GREM1 in MSCs remains unclear. Therefore, we assessed putative beneficial effects on MSC-based therapy...

10.1002/jcp.25578 article EN Journal of Cellular Physiology 2016-08-31

Overreliance on pesticides has large environmental and human health costs that compel researchers farmers to seek alternative management tactics for crop pests. For insect pests, increasing species diversity via intercropping using semiochemicals alter local arthropod populations have separately proven effective at reducing pest densities. Here, we combine these two in an effort gain better control of Sitobion avenae (Fabricius) (Hemiptera: Aphididae), the English grain aphid, a major cereal...

10.1111/j.1570-7458.2011.01150.x article EN Entomologia Experimentalis et Applicata 2011-08-04

Abstract Exposure to tobacco smoke is a major public health concern that can also affect ophthalmic health. Based on previous work demonstrating the important role of sympathetic nervous system (SNS) in corneal wound repair, we postulated acute exposure (ATSE) may act through SNS impairment repair. Here find ATSE rapidly increases markers inflammatory response normal limbi. After an abrasion injury, exaggerates inflammation, impairs and enhances expression nuclear factor-κB (NF-κB) molecules...

10.1038/s42003-018-0270-9 article EN cc-by Communications Biology 2019-01-24

Whether myogenesis is affected by the maternal gut dysbacteriosis still remains ambiguous. In this study, first we show elevated level of lipopolysaccharides (LPS) in a microbiota dysbiosis mouse model. Second, demonstrate that diameter muscle fibers, limb development, and somitogenesis were inhibited both LPS exposed mice chicken embryos. These might be due to disturbed cell survival key genes which regulate myogenesis. RNA sequencing subsequent validation experiments verified retinoic acid...

10.1096/fj.201902965r article EN The FASEB Journal 2020-03-29

Diet plays a crucial role in shaping the gut microbiota and overall health of animals. Traditionally, silkworms are fed fresh mulberry leaves, artificial diets do not support good health. The aim this study was to explore relationship between dietary transition from leaves effects on physiological changes as model organism. With diversity silkworm increased, proportion Enterococcus Weissella, dominant bacterial species reared diets, decreased, whereas abundance Achromobacter Rhodococcus...

10.3390/ijms25031722 article EN International Journal of Molecular Sciences 2024-01-31

Hyperproteinemia is a metabolic disorder associated with increased plasma protein concentration (PPC) and often clinically complicated by malignant diseases or severe infections. At present, however, research on the molecular mechanism underlying high PPC (HPPC) scant. Here, an animal model of primary hyperproteinemia was constructed in invertebrate ( Bombyx mori) to investigate effects HPPC circulating blood cells. Results showed that affected cell homeostasis, leading reactive oxygen...

10.24272/j.issn.2095-8137.2021.397 article EN 动物学研究 2022-01-01

Abstract Artificial diets for silkworms overcome the seasonal limitations of traditional rearing methods with fresh mulberry leaves. However, current wet artificial diets, steamed at high temperatures, are not favored by silkworms, and they cumbersome challenging to preserve. These conditions adversely affected development diet-based sericulture production. In this study, we disinfected dry powder radiation added distilled water without steaming before use. Then, nutritional value finished...

10.1093/jee/toae014 article EN Journal of Economic Entomology 2024-01-24

Growing evidence suggests an adverse impact of gut microbiota dysbiosis on human health. However, it remains unclear whether embryonic osteogenesis is affected by maternal dysbacteriosis. In this study, we observed that elevated lipopolysaccharide (LPS) levels led to skeletal developmental retardation in established mouse model dysbiosis. Using chick embryos exposed dysbacteriosis-derived LPS, found restriction the development long bones as demonstrated Alcian blue and alizarin red staining....

10.3390/ijms21072518 article EN International Journal of Molecular Sciences 2020-04-04

Metabolic disorders of the circulatory system animals (e.g., hyperglycemia and hyperlipidemia) can significantly affect immune function; however, since there is currently no reliable animal model for hyperproteinemia, its effects on immunity remain unclear. In this study, we established an hyperproteinemia in invertebrate silkworm model, with a controllable plasma protein concentration (PPC) primary disease effects. We evaluated influence innate immunity. The results showed that high PPC...

10.3390/biology10020112 article EN cc-by Biology 2021-02-03

The transgenesis of silkworms is an important way to innovate genetic resources and silk function. However, the silk-gland (SG) transgenic silkworms, which most concerned target tissue sericulture, often suffers from low vitality, stunting other problems, reasons are still unknown. This study trans engineered recombinant Ser3, a middle gland (MSG) specific expression gene, in posterior (PSG) silkworm, studied hemolymph immune melanization response changes mutant pure line SER (Ser3+/+)....

10.3390/insects14030245 article EN cc-by Insects 2023-02-28

Objective To investigate the neuroprotection role of muscone at early phase after traumatic brain injury(TBI) in rats. Methods A total 120 SD rats were randomly divided into sham group, TBI group and (0.9 mg/kg) with 40 per group. Each was examined postinjury four different time points (12 h, 24 3 d 7 d), each including 10 rats. Left-sided fluid percussion models utilized study. Sham underwent craniotomy only. Rats received intraperitoneal injection immediately then every day injury....

10.3760/cma.j.issn.1001-8050.2016.06.016 article EN Zhonghua chuangshang zazhi 2016-06-15

The latent bud regeneration ability at the center of Pinus massoniana needle bundles is strong, and can provide a large amount material for asexual reproduction.Topping P. induce sprouting, but mechanisms underlying sprouting process are unclear.In this study, physiological indexes were examined during coniferous buds.Additionally, transcript expression profile was obtained by high-throughput sequencing.The results showed that increases in N endogenous hormone indole-3-acetic acid (IAA)...

10.15666/aeer/1901_727737 article EN Applied Ecology and Environmental Research 2021-01-01

Abstract From the perspective of urban renewal, this paper takes old factory area Liuzhou City as an example, and renovates develops blocks that need to be replaced by functions. This work uses scientific theories guide renewal transformation, principle seeking truth from facts people-oriented realizes transformation through various means. In addition, culture workers has been reshaped, industrial memory revived, importance renovation sustainable development districts clearly explained, all...

10.1088/1742-6596/2468/1/012139 article EN Journal of Physics Conference Series 2023-04-01
Coming Soon ...