A5056239688- Antimicrobial Peptides and Activities
- Biochemical and Structural Characterization
- Probiotics and Fermented Foods
- Tribology and Lubrication Engineering
- Metalloenzymes and iron-sulfur proteins
- Folate and B Vitamins Research
- Osteoarthritis Treatment and Mechanisms
- Plant and Biological Electrophysiology Studies
- Plant Reproductive Biology
- Neurobiology and Insect Physiology Research
- Natural product bioactivities and synthesis
- Graphene and Nanomaterials Applications
- Listeria monocytogenes in Food Safety
- Head and Neck Surgical Oncology
- Access Control and Trust
- Meat and Animal Product Quality
- Invertebrate Immune Response Mechanisms
- Nuclear Engineering Thermal-Hydraulics
- Mycobacterium research and diagnosis
- Enterobacteriaceae and Cronobacter Research
- Biomedical and Engineering Education
- Genetics, Aging, and Longevity in Model Organisms
- Adhesion, Friction, and Surface Interactions
- Adversarial Robustness in Machine Learning
- Biotin and Related Studies
Hong Kong University of Science and Technology
2017-2024
University of Geneva
2022-2024
University of Hong Kong
2017-2024
Peking University
2024
Shaanxi University of Technology
2024
Peking University Third Hospital
2024
Southern Medical University
2023
Shandong University of Traditional Chinese Medicine
2023
Zhujiang Hospital
2023
Guangdong Academy of Forestry
2023
Host defense peptides (HDPs) are one of the potentially promising agents for infection diseases due to their broad spectrum and low resistance rate, but clinical applications limited by proteolytic instability, high-cost, complicated synthesis process. Here, we report a host-defense-peptide-mimicking β-peptide polymer that resists proteolysis have enhanced activity under physiological conditions, excellent antimicrobial efficiency even at high density bacteria, cost preparation. The...
Recently, the DeepSeek series of models, leveraging their exceptional reasoning capabilities and open-source strategy, is reshaping global AI landscape. Despite these advantages, they exhibit significant safety deficiencies. Research conducted by Robust Intelligence, a subsidiary Cisco, in collaboration with University Pennsylvania, revealed that DeepSeek-R1 has 100\% attack success rate when processing harmful prompts. Additionally, multiple companies research institutions have confirmed...
Significance Plants respond to a delicate force signal, such as light touch, similar animal neural systems, demonstrated by thigmotropism, thigmonastic movement, and thigmomorphogenesis. To understand the force-signaling networks, we applied stable isotope labeling in Arabidopsis (SILIA)-based quantitative posttranslational modification proteomics assess protein phosphorylation changes subjected 40-second cotton-swab identified 4,895 nonredundant phosphopeptides, 579 of which are previously...
Antimicrobial peptide is one important component of the first protective barrier organisms. They not only have potent antimicrobial activity which can protect body from invading pathogens, but also participate in immune regulation body. In this study, a Brevinin-1 named by Brevinin-1GHd was identified Hoplobatrachus rugulosus , and similarity mature sequence among Brevinin-1GHd, Brevinin-1HL Brevinin-1GHa supported close species relationship between H. Hylarana latouchii guertheri ....
Developing targeted delivery nanosystems for delivering chemotherapeutic anticancer drugs specifically to cancerous tissues with improvement in the specificity of different cancer cells can result high therapeutic efficacy and low toxicity healthy tissues. Herein, we proposed synthesis a multifunctional nanodelivery system, folic acid (FA) decorating nanographene oxide (nGO) functionalized poly(ethylene glycol) (PEG), called pGO-FA, good biocompatibility performance hydrophobic...
Abstract Background Escherichia fergusonii is a common conditionally pathogenic bacterium that infects humans and animals. E. has been reported to cause diarrhea, respiratory disease, septicemia, but it rarely skin infections in isolated from the muscular tissue of Chinese pangolin ( Manis pentadactyla aurita ). To date, there have no reports pangolins with clinical signs diseases. Case presentation This case report describes subadult (bodyweight: 1.1 kg) female wild rescue pustules...
Knee osteoarthritis (KOA) is mainly characterized by degenerative changes in the knee joint's cartilage and surrounding soft tissues. The efficacy of Tuina treating KOA has been confirmed, but underlying mechanism needs to be investigated. This study aims establish a scientifically feasible rabbit model treated with reveal mechanisms. For this, 18, 6-month-old normal-grade male New Zealand rabbits were randomly divided into sham, model, groups, 6 each group. was established injecting 4%...
This study analyzed the effect of initial inoculum proportions on Listeria monocytogenes growth when cocultured with two different Weissella viridescens strains. W. C1 had a strong antimicrobial L. which may be due to acid, H2O2 and proteinaceous nature its compounds. C2 no properties. In liquid coculture, inhibited growth, while did not. Thus, showed same in coculture as monoculture. Coculturing at laboratory media growth. help characterize interactions between viridescens.
The tumour specificities and potency of miniaturized cancer targeting peptides are among the major issues current research.Over 100 were evaluated in this study.According to observations, leucine could sustain antibacterial anticancer efficacy (leucine/lysine)n ((L/K)n) across different assay conditions, whereas (valine/lysine)n ((V/K)n) (isoleucine/lysine)n ((I/K)n) less effective.Tumour peptides, consisting a leucine/lysine peptide an antibody complementarity-determining region (CDR)...
Plants responding to both intracellular and extracellular mechanical stimulations (or force signals) develop special morphological changes, a called thigmomorphogenesis. In past decades, several signaling components have been identified reported for being involved in the mechanotransduction (e.g., calcium ion binding proteins jasmonic acid biosynthesis enzymes). However, relatively slow pace of research study or thigmomorphogenesis is largely attributed two reasons: requirement laborious...
Wind is one of the most prevalent environmental forces entraining plants to develop various mechano-responses, collectively called thigmomorphogenesis. Largely unknown how transduce these versatile wind force signals downstream nuclear events and development thigmomorphogenic phenotype or anemotropic response. To identify molecular components at early steps signaling, two mechanical signaling-related phosphoproteins, identified from our previous phosphoproteomic study Arabidopsis touch...
Under the action of flow field force and constraint reaction negative rotor positive rotor, twin screw compressor shell will produce vibration, which affect life parts noise. The rotors restraint are calculated by fluid-structure coupling method. inherent frequency is solved modal analysis, resonance analyzed during meshing process. On this basis, used as vibration excitation sources, response under studied. research results can provide some reference for optimized design structure.
Industrial colleges represent a new form of vocational and are an innovative school-enterprise cooperation model. The main participants in this collaborative construction industries, enterprises, schools. In higher education applied undergraduate programs, the development industrial has become relatively mature. However, technical schools, is still its initial stage. There no mature experiences to refer to. Therefore, determining talent cultivation mode that practical distinct from...