A5037098355- Software Engineering Research
- Software Engineering Techniques and Practices
- Advanced Software Engineering Methodologies
- Service-Oriented Architecture and Web Services
- Software Reliability and Analysis Research
- Chronic Lymphocytic Leukemia Research
- Software System Performance and Reliability
- Software Testing and Debugging Techniques
- Lymphoma Diagnosis and Treatment
- Open Source Software Innovations
- Scientific Computing and Data Management
- Silicon Carbide Semiconductor Technologies
- Logic, programming, and type systems
- Electroconvulsive Therapy Studies
- Parkinson's Disease Mechanisms and Treatments
- Schizophrenia research and treatment
- Model-Driven Software Engineering Techniques
- Business Process Modeling and Analysis
- Neurological disorders and treatments
- Chronic Myeloid Leukemia Treatments
- Takotsubo Cardiomyopathy and Associated Phenomena
- Fish biology, ecology, and behavior
- Transcranial Magnetic Stimulation Studies
- Manufacturing Process and Optimization
- Genetic Associations and Epidemiology
University of Kaiserslautern
2025
Yale University
2024
Maine Medical Center
2022
Maine Medical Center Research Institute
2022
Tel Aviv University
2022
MaineHealth
2022
The Ohio State University
2016-2021
ABB (Switzerland)
2016-2019
Wills Eye Hospital
2011-2016
Iowa State University
2008-2016
An effective data collection method for evaluating software development methodologies and studying the process is described. The uses goal-directed to evaluate with respect claims made them. Such are used as a basis defining goals of collection, establishing list questions interest be answered by analysis, set categorization schemes, designing form. collected based on changes during development, obtained when made. To ensure accuracy data, validation performed concurrently collection....
Reducing the number of software failures is one most challenging problems production. We assume that development proceeds as a series changes and model probability change to will cause failure. use predictors based on properties itself. Such include size in lines code added, deleted, unmodified; diffusion its component subchanges, reflected files, modules, subsystems touched, or changed; several measures developer experience; type subchanges (fault fixes new code). The built historic...
This paper discusses the organization of software that is inherently complex because very many arbitrary details must be precisely right for to correct. We show how design technique known as information hiding, or abstraction, can supplemented by a hierarchically structured document, which we call module guide. The guide intended allow both designers and maintainers identify easily parts they understand, without reading irrelevant about other software. includes an extract from illustrate our...
The article describes how to perform domain engineering by identifying the commonalities and variabilities within a family of products. Through interesting examples dealing with reuse libraries, design patterns, programming language design, authors suggest systematic scope, commonalities, approach formal analysis. Their SCV analysis has been an integral part FAST (Family-oriented Abstraction, Specification, Translation) technology applied over 25 domains at Lucent Technologies.
Although many new software design techniques have emerged in the past 15 years, there been few changes to procedures for reviewing designs produced using these techniques. This paper describes an improved technique, based on following ideas, designs.The efforts of each reviewer should be focussed those aspects that suit his experience and expertise.The characteristics reviewers needed explicitly specified before are selected.Reviewers asked make positive assertions about rather than simply...
The development of highly effective targeted agents for chronic lymphocytic leukemia offers the potential fixed-duration combinations that achieve deep remissions without cytotoxic chemotherapy.This phase II study tested a combination regimen obinutuzumab, ibrutinib, and venetoclax total 14 cycles in both patients with treatment-naïve (n = 25) relapsed or refractory to determine response therapy safety.The primary end point was rate complete remission undetectable minimal residual disease by...
Acalabrutinib is a selective irreversible Bruton tyrosine kinase (BTK) inhibitor that does not affect IL2-associated or antibody-dependent cellular cytotoxicity, making it an attractive candidate for combination therapy with anti-CD20 antibodies. We investigated acalabrutinib plus obinutuzumab in phase Ib/II study (NCT02296918) of patients treatment-naïve relapsed/refractory chronic lymphocytic leukemia (CLL). Nineteen and 26 were treated (100 mg twice daily) until progression (cycle 1: 100...
Because of economic, political, and practical needs, businesses regularly distribute their software production globally. Participants at the different development sites often suffer inhibited communication coordination because they are remote from each other. One result affected might be reduced productivity an increased interval. We look for technical solutions to accommodate business needs distributed development. In doing so, we investigate quantitative approaches distributing work across...
Test coverage is sometimes used to measure how thoroughly software tested and developers vendors use it indicate their confidence in the readiness of software. This survey studies compares 17 coverage-based testing tools primarily focusing on, but not restricted to, measurement. We also features such as program prioritization for testing, assistance debugging, automatic generation test cases customization reports. Such make more useful practical, especially large-scale, commercial...
Architecture reviews have evolved over the past decade to become a critical part of our continuing efforts improve state affairs. We use them identify project problems before they costly fix and provide timely information upper management so that can make better-informed decisions. It provides foundation for reuse, using commercially available software, getting marketplace fast. The also help best practices projects socialize such across organization, thereby improving organization's quality...
ABSTRACT Aims Topiramate has shown efficacy at facilitating abstinence from alcohol and cocaine abuse. This double‐blind, placebo‐controlled out‐patient trial tested topiramate for treating methamphetamine addiction. Design Participants ( n = 140) were randomized to receive or placebo (13 weeks) in escalating doses 50 mg/day the target maintenance of 200 weeks 6–12 (tapered week 13). Medication was combined with weekly brief behavioral compliance enhancement treatment. Setting The conducted...
An effective data collection methodology for evaluating software development methodologies was applied to five different projects. Results and from three of the projects are presented. Goals included characterizing changes, errors, projects, programmers, identifying error detection correction techniques, investigating ripple effects.
We describe in this paper an effective data collection method for evaluating software development methodologies, from definition of the objectives to analysis results. show how can answer questions with respect successfully goals methodology are met. The A-7 requirements document is used as example. provide results analyses conducted partway through flight cycle, and discuss utility information obtained by such partial analyses. Results study that feasible useful when performed part...
We set out to answer a question we were asked by software project management: how much effort remains be spent on specific and will that distributed over time? To this propose model based the concept each modification may cause repairs at some later time investigate its theoretical properties application several projects in Avaya predict plan development resource allocation. Our presents novel unified framework effort, schedule, defects of project. The results applying confirm fundamental...
This study aimed to assess the feasibility of screening for early emerging mental experiences model, which is designed screen psychosis in settings with integrated primary and health care. Psychosis screening, triage, engagement processes (July 2021-June 2022) were implemented four care practices serving approximately 7,000 patients targeted age range (14-26 years). Practice community stakeholders participated project's design development. specialists provided training case consultation...
Previous studies have reported genetic linkage evidence for a schizophrenia gene on chromosome 15q. Here, 15 was examined by analysis using 166 families, each with two or more affected subjects. The assembled from multiple centers the Department of Veterans Affairs Cooperative Study Program, consisted 392 sampled subjects and 216 sibling pairs. By DSM-III-R criteria, 360 (91.8%) had diagnosis 32 (8.2%) were classified as schizo-affective disorder, depressed. Participating families diverse...
Test coverage is sometimes used as a way to measure how thoroughly software tested. Coverage by developers and vendors indicate their confidence in the readiness of software. This survey studies compares 17 coverage-based testing tools focusing on, but not restricted measurement. We also additional features, including program prioritization for testing, assistance debugging, automatic generation test cases, customization reports. Such features make more useful practical, especially...
OBJECTIVE The Patient-Reported Outcomes Measurement Information System Cognitive Function-Concerns® (PROMIS®-CF-Concerns) assesses self-reported cognitive complaints. Construct validity data for the CF-Concerns are few. To add to literature, an analysis of criterion complaints (European Organisation Research and Treatment Cancer-Cognitive Functioning subscale [EORTC-CF]) performance (neuropsychological tests memory [NIH Toolbox Auditory Verbal Learning Test] verbal fluency [Controlled Oral...
A software product line is a family of products that share common features to meet the needs market area. Systematic processes have been developed dramatically reduce cost line. Such product-line engineering proven practical and effective in industrial use, but are not widely understood. The Family-Oriented Abstraction, Specification Translation (FAST) process has used successfully at Lucent Technologies over 25 domains, providing productivity improvements as much four one. In this paper, we...