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Research Areas
- Neuroinflammation and Neurodegeneration Mechanisms
- RNA Interference and Gene Delivery
- Inflammation biomarkers and pathways
- Traumatic Brain Injury and Neurovascular Disturbances
- Immune cells in cancer
- S100 Proteins and Annexins
Institut Pasteur de Montevideo
2019-2023
10.1038/s41434-019-0073-8
article
EN
Gene Therapy
2019-03-29
Emerging evidence suggests that immune receptors may participate in many aging-related processes such as energy metabolism, inflammation, and cognitive decline. CD300f, a TREM2-like lipid-sensing receptor, is an exceptional receptor it integrates activating inhibitory cell-signaling pathways modulate efferocytosis, microglial metabolic fitness. We hypothesize CD300f can regulate systemic ultimately healthy lifespan. closely followed several cohorts of two strains CD300f-/- WT mice both sexes...
10.1016/j.celrep.2023.113269
article
EN
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Cell Reports
2023-10-01
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