Fabio Andrés Cawen

ORCID: 0000-0001-5813-9054
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About
Contact & Profiles
Research Areas
  • Neuroinflammation and Neurodegeneration Mechanisms
  • RNA Interference and Gene Delivery
  • Inflammation biomarkers and pathways
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Immune cells in cancer
  • S100 Proteins and Annexins

Institut Pasteur de Montevideo
2019-2023

Emerging evidence suggests that immune receptors may participate in many aging-related processes such as energy metabolism, inflammation, and cognitive decline. CD300f, a TREM2-like lipid-sensing receptor, is an exceptional receptor it integrates activating inhibitory cell-signaling pathways modulate efferocytosis, microglial metabolic fitness. We hypothesize CD300f can regulate systemic ultimately healthy lifespan. closely followed several cohorts of two strains CD300f-/- WT mice both sexes...

10.1016/j.celrep.2023.113269 article EN cc-by Cell Reports 2023-10-01
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