A5100757230- Family Caregiving in Mental Illness
- Mental Health Treatment and Access
- Mental Health and Patient Involvement
- Schizophrenia research and treatment
- MRI in cancer diagnosis
- Radiomics and Machine Learning in Medical Imaging
- Resilience and Mental Health
- COVID-19 and Mental Health
- Adolescent and Pediatric Healthcare
- Healthcare Decision-Making and Restraints
- Suicide and Self-Harm Studies
- Lanthanide and Transition Metal Complexes
- Healthcare professionals’ stress and burnout
- Family and Patient Care in Intensive Care Units
- Personality Disorders and Psychopathology
- Bipolar Disorder and Treatment
- Electroconvulsive Therapy Studies
- Genetic factors in colorectal cancer
- Medical Imaging Techniques and Applications
- Nursing education and management
- Healthcare innovation and challenges
- Viral Infections and Vectors
- Posttraumatic Stress Disorder Research
- Psychopathy, Forensic Psychiatry, Sexual Offending
- Obsessive-Compulsive Spectrum Disorders
Second Military Medical University
2016-2025
Institute of Mental Health
2013-2024
First Affiliated Hospital of Xinxiang Medical University
2024
Xinxiang Medical University
2022-2024
Henan Provincial People's Hospital
2022
Jinzhou Medical University
2016-2018
Genecast (China)
2018
Beijing VDJBio (China)
2015
National University of Singapore
2012
Albert Einstein College of Medicine
2003-2010
Abstract The recently reported Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe illness in humans with an approximately 30% mortality rate. envelope spike glycoprotein on the surface of MERS-CoV mediates receptor binding, membrane fusion and viral entry. We previously two human monoclonal antibodies that target binding domain (RBD) exhibit strong neutralization activity against live pesudotyped infection. Here we determined crystal structure RBD bound to Fab fragment...
Abstract Background Chinese nurses working with immense stress may have issues burnout during COVID-19 regular prevention and control. There were a few studies investigating status of associated factors among nurses. However, the relationships remained unclear. Objectives To investigate nurses’ Methods 784 completed questionnaires including demographics, Generalized Anxiety Disorder-7, Patient Health Questionnaire-9, Insomnia Severity Index, Impact Event Scale-revised, Perceived Social...
Individuals with severe and enduring mental health challenges continued to consume services for an average of 13 years as they needed multiple acute psychiatric admissions due the experienced in their everyday activities. As caregivers individuals challenges, often bear brunt caregiving through assistance activities daily living (ADL), providing emotional support ensuring medication compliance loved ones. When caring ones, reported psychological stress, social isolation exhaustion stressors...
Peers support specialists have positive impacts on the mental health of their service users. However, less is known about how changes as a result activities.We followed 10 peer over first year employment and interviewed them thrice. We used grounded theory to analyse way in which participants changed.Self-reported our did not change course study. role help grow learn condition strengths. While sharing past experiences could be taxing, they learned harness recovery journey without risking...
The reported rates of personality disorder (PD) in subjects with schizophrenia (SZ) are quite varied across different countries, and less is known about the heterogeneity PD among SZ. We examined co-morbidity patients who stable phase SZ.850 were randomly sampled from diagnosed SZ psychiatric psycho-counseling clinics at Shanghai Mental Health Center. Co-morbidity PDs was assessed through preliminary screening administered several modules SCID-II. Evidence evaluated by comparing those...
Despite the rising recognition of personal recovery, there is a lack research on recovery in individuals with psychosis Singapore. This study aims to evaluate psychometric properties QPR-15 using CHIME framework and examine its associations clinical factors. Sixty-six stable outpatients were recruited assessed at two time points approximately 2 weeks apart. Convergent validity was examined through Spearman correlations scores CHIME-related psychological factors: connectedness (Ryff subscale-...
The differential influence of therapeutic alliance with different health care professionals on patients' medication adherence has never been examined.Ninety-five stable outpatients (91 patients schizophrenia and 4 schizoaffective disorder) were recruited. Individual, clinical, factors assessed, along drug attitude (10-item Drug Attitude Inventory). Comparison these was made between who identified psychiatrists as the professional most involved in their care, compared other...
Lung cancer has become one of the deadliest tumors in world. Non-small cell lung (NSCLC) is most common type cancer, accounting for approximately 80%-85% all cases. This study aimed to investigate value diffusion kurtosis imaging (DKI), diffusion-weighted (DWI) and 2-[18F]-fluoro-2-deoxy-D-glucose positron emission tomography (18F-FDG PET) differentiating squamous carcinoma (SCC) adenocarcinoma (AC) evaluate correlation each parameter with stage proliferative status Ki-67.Seventy-seven...
To investigate the efficacy of three-compartment restriction spectrum imaging (RSI), diffusion kurtosis (DKI), and diffusion-weighted (DWI) in assessment lymph node metastases (LNM) rectal cancer.
Abstract The current study seeks to determine how peer support roles change as specialists’ positions within organizations and departments mature. We followed ten specialists over the course of a year, interviewing them at three points, starting approximately months after they began working specialists. used an inductive process analyze our data guidelines on structuring longitudinal qualitative trajectories divide into watershed moments. Our participants worked in variety hospital, their...
To determine the effectiveness of a peer-led self-management programme for people with schizophrenia in reducing psychotic symptom severity, hospital readmission and psychiatric consultation enhancing cognition, empowerment, functioning level, medication adherence, perceived recovery, quality life social support.Several programmes have been developed to empower patients severe mental illness achieving recovery. Research suggests that positive effects on patient However, existing evidence is...
The Occupational Self Assessment (OSA) measures two constructs from the Model of Human Occupation: occupational competence and identity. In field mental health, recovery movement has sparked discussions about what constitutes personal, clinical, functional recovery. However, how occupation-based terminologies are related to framework is unclear.To elucidate domains psychological OSA's identity in order inform therapy practice arena.Cross-sectional study.Outpatient health unit.Sixty-six...
Influenza A virus (IAV), a highly pathogenic to human beings, is most susceptible mutation and thus causes rapid, severe global pandemics resulting in millions of fatalities worldwide. Since resistance the existing anti-influenza drugs developing, innovative inhibitors with different mode action are urgently needed. The lead compound 6092B-E5 has proven be an effective antiviral reagent our previous work. Using principles substitution bioisosterism indole ring, six series novel anti-IAV...
To explore the value of PET/MRI, including diffusion kurtosis imaging (DKI), weighted (DWI) and positron emission tomography (PET), for distinguishing between benign malignant solitary pulmonary lesions (SPLs) predicting histopathological grading SPLs. Chest PET, DKI DWI scans 73 patients with SPL were performed by PET/MRI. The apparent coefficient (ADC), mean diffusivity (MD), (MK), maximum standard uptake (SUVmax), metabolic total volume (MTV) lesion glycolysis (TLG) calculated. Student's...
Abstract Background Though the severe prevention and control measures faced by Chinese nurses had changed during normalisation stage of coronavirus 2019 (COVID-19) pandemic, they still worked under great stress. Due to a lack related evidence, we aimed investigate prevalence correlates post-traumatic stress disorder (PTSD) among COVID-19 pandemic measures. Methods Using convenience sampling, recruited 784 in Jiangsu province, China complete survey via their mobile devices. We used...