A5045293157- Health Systems, Economic Evaluations, Quality of Life
- Global Health Care Issues
- Healthcare Policy and Management
- Healthcare cost, quality, practices
- Urinary Tract Infections Management
- Health disparities and outcomes
- Economic and Environmental Valuation
- Patient Satisfaction in Healthcare
- Antibiotic Use and Resistance
- Global Maternal and Child Health
- Genomics and Rare Diseases
- Employment and Welfare Studies
- COVID-19 Pandemic Impacts
- Antibiotic Resistance in Bacteria
- Pharmaceutical Economics and Policy
- Clinical practice guidelines implementation
- Pediatric Urology and Nephrology Studies
- Chronic Disease Management Strategies
- Primary Care and Health Outcomes
- Obesity, Physical Activity, Diet
- Nutrition and Health in Aging
- Obesity and Health Practices
- Hemoglobinopathies and Related Disorders
- Aging, Health, and Disability
- Neurosurgical Procedures and Complications
Universidad de Las Palmas de Gran Canaria
2016-2025
Health Research Institute of the Balearic Islands
2022
Centro de Investigación Biomédica en Red
2014-2021
Fundación Canaria de Investigación Sanitaria
2017-2019
University College London
2009-2018
Manufacturing Advocacy & Growth Network (United States)
2018
Servicio Canario de la Salud
2018
Spanish Clinical Research Network
2016-2017
Universidad de La Laguna
2013-2016
MRC Clinical Trials Unit at UCL
2013-2014
The cost of generating a quality-adjusted life year (QALY) within National Health Service provides an approximation the average opportunity funding decisions. This information can be used to inform cost-effectiveness threshold. aim this paper is estimate per QALY at Spanish Service. We exploit variation across 17 regional health services and exogenous changes in expenditure that took place as consequence economic crisis over 5 years data. conduct fixed effect models use instrumental variable...
Increasing incidence of and mortality from skin cancer are posing a large financial burden on the NHS in England. Information provided by cost-of-illness (CoI) studies used policy making particularly useful for measuring potential savings averting case disease. We estimate cost England, model future costs up to 2020. compare two costing approaches (top-down bottom-up). that due were range £106–£112 million 2008. These figures very closely related those Department Health (estimated be £104.0...
Abstract Background Complicated urinary tract infections (cUTIs) are responsible for a major share of all antibiotic consumption in hospitals. We aim to describe risk factors treatment failure and mortality among patients with cUTIs. Methods A multinational, multicentre retrospective cohort study, conducted 20 countries Europe the Middle East. Data were collected from patients’ files on hospitalised diagnosis cUTI during 2013-2014. Primary outcome was failure, secondary outcomes included 30...
Background: The COVID-19 pandemic has hit both the Spanish economy and population’s health hard. result is an unprecedented economic social crisis due to uncertainty about remedy socioeconomic effects on people’s lives. Methods: We performed a retrospective analysis of macroeconomic impact in 2020 using key indicators for 17 Autonomous Communities (ACs) country. National statistics were examined search impacts or anomalies occurring since beginning pandemic. To estimate strength each...
Medical device companies are under growing pressure to provide health-economic evaluations of their products. Cost-effectiveness analyses commonly undertaken as a one-off exercise at the late stage development new technologies; however, benefits an iterative use economic evaluation during process products have been acknowledged in literature. Furthermore, Bayesian methods within health technology assessment has shown be particular value dynamic framework appraisal when information becomes...
Objective Complicated urinary tract infections (cUTIs) impose a high burden on healthcare systems and are frequent cause of hospitalisation. The aims this paper to estimate the cost per episode patients hospitalised due cUTI explore factors associated with cUTI-related costs in eight countries prevalence multidrug resistance (MDR). Design This is multinational observational, retrospective study. mean was computed by multiplying volume use for each patient unit item care summing across all...
Patients with complicated urinary tract infections (cUTIs) frequently receive broad-spectrum antibiotics. We aimed to determine the prevalence and predictive factors of multidrug-resistant gram-negative bacteria in patients cUTI.This is a multicenter, retrospective cohort study south eastern Europe, Turkey Israel including consecutive cUTIs hospitalised between January 2013 December 2014. Multidrug-resistance was defined as non-susceptibility at least one agent three or more antimicrobial...
Background Nursing home (NH) residents are frequently treated with antibiotics for urinary tract infections (UTIs), often due to overdiagnosis. The aim of this study was evaluate the proportion potentially unnecessary antibiotic use suspected UTIs in NHs across eight European countries.
Objective: To evaluate the impact of a multifaceted antimicrobial stewardship intervention on potentially unnecessary antibiotic prescribing. Material and methods: Before after quality control study carried out in three different settings—general practice, out-of-hours services, nursing homes—in Spain. Healthcare professionals (both doctors nurses) self-registered common infections using specific template for each setting before (2022) (2023) receiving 5-hour prudent use. Results:...
Abstract Background Centralizing specialist cancer surgery services aims to reduce variations in quality of care and improve patient outcomes, but increases travel demands on patients families. This study aimed evaluate preferences patients, health professionals members the public for characteristics associated with centralization. Methods A discrete-choice experiment was conducted, using paper electronic surveys. Participants comprised: former current (at any stage treatment) prostate,...
Purpose This paper aims to provide an estimation of the costs coronavirus (COVID-19) pandemic with a special focus on Spain. Costs include macroeconomic foregone gross domestic product (GDP) attributable and direct indirect prevention, treatment lost productivity. study also analyzes cost-effectiveness test-tracking-quarantine (TTQ) strategy in Design/methodology/approach The GDP are estimated for different countries areas by comparing present forecasts 2020 2021 counterfactuals before...
Background: Physical disability and psychologic morbidity are frequent important complications of severe trauma injury with serious consequences for long-term health-related quality life (HRQOL). Little prospective data exist, however, in a global population on the risk factors poor HRQOL. Methods: The CONTROL trial was prospective, randomized, double-blinded, multicenter, placebo-controlled conducted from August 2005 to September 2008. HRQOL assessed 3 months after using Polytrauma Outcome...
Previous studies have found the socioeconomic gradient in health among adolescents to be lower than that observed during childhood and adulthood. The aim of this study was examine income-related inequalities health-related behaviour across lifespan England explore 'equalisation' adolescence.We used five years data (2006-2010) from Health Survey for six indicators: self-assessed general health, longstanding illness, limiting psychosocial wellbeing, obesity smoking status. We ran separate...
Complicated urinary tract infections (cUTIs) are among the most frequent health-care-associated infections. In patients with cUTI, Pseudomonas aeruginosa deserves special attention, since it can affect serious underlying conditions. Our aim was to gain insight into risk factors and prognosis of P. cUTIs in a scenario increasing multidrug resistance (MDR).This multinational, retrospective, observational study at 20 hospitals south southeastern Europe, Turkey, Israel including consecutive cUTI...
The probability of reimbursement is a key factor in determining whether to proceed with or abandon product during its development. purpose this article illustrate how the methods iterative Bayesian economic evaluation proposed literature can be incorporated into development process new medical devices, adapting them face relative scarcity data and time that characterizes process.A 3-stage was applied: an early phase which simple allow for quick prioritization competing products; mid-stage...
There is a well-documented social gradient in obesity most developed countries. Many previous studies have conventionally categorised individuals according to their body mass index (BMI), focusing on those above certain threshold and thus ignoring large amount of the BMI distribution. Others used linear models, relying mean effects that may mask substantial heterogeneity socioeconomic variables across population.In this study, we measure distribution adult population Spain over past two...
Chronic diseases are posing an increasing challenge to society, with the associated burden falling disproportionally on more deprived individuals and geographical areas. Although existence of a socioeconomic health gradient is one main concerns policy across world, information systems commonly do not have reliable data detect monitor inequalities inequities. The objectives this study were measure level socioeconomic-related inequality in prevalence chronic investigate extent direction...
Background: The COVID-19 pandemic has hit the Spanish economy hard. result is an unprecedented economic and social crisis due to uncertainty about remedy, socio-economic effects on people’s lives. Methods: We performed a retrospective analysis of macro-economic impact in 2020, using principal indicators productive model. National statistics were examined search for impacts or anomalies occurring since beginning pandemic. To estimate strength each analysed, we used Bayesian...