- Health Systems, Economic Evaluations, Quality of Life
- Dementia and Cognitive Impairment Research
- Machine Learning in Healthcare
- Healthcare Policy and Management
- Antibiotic Resistance in Bacteria
- Chronic Disease Management Strategies
- Urinary Tract Infections Management
- Health disparities and outcomes
- Mental Health Treatment and Access
- Delphi Technique in Research
- Schizophrenia research and treatment
- Blood Pressure and Hypertension Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Colorectal Cancer Screening and Detection
- Telemedicine and Telehealth Implementation
- Clinical practice guidelines implementation
- Genetic factors in colorectal cancer
- Health, Environment, Cognitive Aging
- Nephrotoxicity and Medicinal Plants
- Enterobacteriaceae and Cronobacter Research
- Healthcare cost, quality, practices
- Heart Failure Treatment and Management
- Hip and Femur Fractures
- Atrial Fibrillation Management and Outcomes
- Functional Brain Connectivity Studies
Bioef - Fundación Vasca de Innovación e Investigación Sanitarias
2024
Osasun Sistemen Ikerketa Institutua
2020-2023
Institute for Systems Biology
2023
BioCruces Health research Institute
2023
Association of Electronic and Information Technologies
2020-2022
Osakidetza
2020-2022
Hospital Alto Deba
2020
Biogipuzkoa Health Research Institute
2020
Manufacturing Advocacy & Growth Network (United States)
2018
Complicated urinary tract infections (cUTIs) are among the most frequent health-care-associated infections. In patients with cUTI, Pseudomonas aeruginosa deserves special attention, since it can affect serious underlying conditions. Our aim was to gain insight into risk factors and prognosis of P. cUTIs in a scenario increasing multidrug resistance (MDR).This multinational, retrospective, observational study at 20 hospitals south southeastern Europe, Turkey, Israel including consecutive cUTI...
Neuropsychiatric symptoms (NPS) are the leading cause of social burden dementia but their role is underestimated.The objective study was to validate predictive models separately identify psychotic and depressive in patients diagnosed with using clinical databases representing whole population inform decision-makers.First, we searched electronic health records 4,003 NPS. Second, machine learning (random forest) algorithms were applied build separate for symptom clusters training set (N =...
Due to population ageing and medical advances, people with advanced chronic diseases (ACD) live longer. Such patients are even more likely face either temporary or permanent reduced functional reserve, which typically further increases their healthcare resource use the burden of care on caregiver(s). Accordingly, these caregiver(s) may benefit from integrated supportive provided via digitally supported interventions. This approach maintain improve quality life, increase independence,...
Abstract Background Value-based healthcare (VBHC) is a conceptual framework to improve the value of by health, care-process and economic outcomes. Benchmarking should provide useful information identify best practices therefore good instrument quality across organizations. This paper aims proof-of-concept feasibility an international VBHC benchmarking in breast cancer, with ultimate aim being used share data-driven approach among organizations from different health systems. Methods In VOICE...
Health-related quality of life (HRQL) is a key factor in making anticoagulant treatment decisions. The objective this study was to assess the HRQL patients with nonvalvular atrial fibrillation by type: direct oral anticoagulants (DOACs) or vitamin K antagonists (VKAs).We carried out cross-sectional observational clinical practice data, gathering demographic and variables. measured using 5-level 5-dimension EuroQol questionnaire (EQ-5D-5L). Differences between groups as EQ-5D-5L were analyzed...
Objective The first and second rounds of the Basque programme for organised colorectal cancer screening were implemented between 2009 2014. Our objective was to measure changes in incidence, tumour, node, metastasis staging distribution metastasis-adjusted survival patients with from 2003 Method Colorectal cases (patients <70 years old) without ≥70 compared during three four-year periods: 2003–2006, 2007–2010 2011–2014 (fully phase). Cox regression, five-year relative probability death...
Abstract Background The LipiDiDiet trial showed that Souvenaid, a medical food, might delay progression to dementia in prodromal Alzheimer’s disease (AD). objective of this study was assess the cost-utility Souvenaid compared placebo patients with AD under conditions applied trial. Methods A discrete event simulation model developed based on and literature review from societal perspective considering direct indirect costs. For both intervention control groups, patient trajectories terms...
To conduct a stratified cost-utility analysis of total versus partial hip arthroplasty as function clinical subtype.All cases this type intervention were analysed between 2010 and 2016 in the Basque Health Service, gathering data on outcomes resource use to calculate cost utility quality-adjusted life years (QALYs) at individual level. The statistical included applying propensity score balance groups, seemingly unrelated regression models incremental ratio plot cost-effectiveness plane....
Abstract Background The value equation of value-based healthcare (VBHC) as a single figure remains ambiguous, closer to theoretical framework than useful tool for decision making. challenge lies in the way patient-centred outcomes (PCOs) might be combined produce numerator. This paper aims estimate weights PCOs provide numerator, which ultimately will allow VBHC reached. Methods A cohort patients diagnosed with breast cancer (n = 690) 6-month follow-up recruited 2019–20 across six European...
The value equation of the Value-based Healthcare (VBHC) as a single figure lies still ambiguous, closer to theoretical framework than useful tool make decisions. challenge in way Patient-Centred Outcomes(PCOs) might be combined produce for multidimensional numerator. This paper aims estimate weights PCOs provide numerator equation, which ultimately will allow reach VBHC figure.A cohort patients diagnosed with breast cancer(n=690) 6-month follow-up recruited 2019/20 across 6-European...
Abstract Rationale, aims and objectives An integrated care program for heart failure (HF) was developed in the Basque Country 2013. The objective of this research to evaluate its effectiveness through number hospital admissions three healthcare organizations (IHOs), taking into account longitudinal nature disease intensity implementation. Methods A retrospective observational study carried out, based on data entered administrative clinical databases between 2014 2018 a total population 230...
Abstract Background 8% of currently under evaluation new drugs for Alzheimer’s disease are intended to treat neuropsychiatric symptoms (NPS). But, the lack their presence in codded format clinical records registries determines that population impact is underestimated. Validation studies required order systematically use real‐world data (RWD) as a source epidemiological information dementia. The objective this study was build and validate predictive models identify both behavioral or...
Abstract Background Neuropsychiatric symptoms (NPS) are the leading cause of social burden dementia but their role is underestimated. The objective study was to validate predictive models separately identify psychotic and depressive in patients diagnosed with using clinical databases representing whole population (real-world data). Methods First, we searched electronic health records 4,003 NPS. Second, machine learning (random forest) algorithms were applied build training sample (N=3,003)...