Igor Larrañaga

ORCID: 0000-0001-9647-0514
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About
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Research Areas
  • Health Systems, Economic Evaluations, Quality of Life
  • Health disparities and outcomes
  • Chronic Disease Management Strategies
  • Dementia and Cognitive Impairment Research
  • Mental Health Treatment and Access
  • Frailty in Older Adults
  • Employment and Welfare Studies
  • COVID-19 epidemiological studies
  • Insurance, Mortality, Demography, Risk Management
  • Heart Failure Treatment and Management
  • Mobile Health and mHealth Applications
  • Schizophrenia research and treatment
  • Health and Medical Education
  • SARS-CoV-2 and COVID-19 Research
  • Healthcare cost, quality, practices
  • Machine Learning in Healthcare
  • Pain Management and Opioid Use
  • Healthcare Policy and Management
  • Healthcare Systems and Technology
  • Global Health Care Issues
  • Vaccine Coverage and Hesitancy
  • Clinical practice guidelines implementation
  • Health, Environment, Cognitive Aging
  • Advanced Fiber Optic Sensors
  • COVID-19 and healthcare impacts

Association of Electronic and Information Technologies
2020-2025

Osakidetza
2017-2025

Osasun Sistemen Ikerketa Institutua
2018-2025

Biogipuzkoa Health Research Institute
2018-2024

BioCruces Health research Institute
2024

Hospital Alto Deba
2016-2023

Spanish Clinical Research Network
2020

The objective of this study was to estimate the incidence and age onset mental disorders diagnosed by gender socioeconomic status (SES) in children, adolescents, young adults up 30 years whole population Basque Country (Spain).All health diagnoses documented Health Service records from 1 January 2003 31 December 2018, were classified into eight clusters: anxiety, attention deficit hyperactivity disorder (ADHD), conduct disorders, depression, psychosis/personality substance use, eating...

10.1007/s00127-023-02425-z article EN cc-by Social Psychiatry and Psychiatric Epidemiology 2023-01-24

Abstract Disability and multimorbidity increase with aging constitute a challenge for the health system. However, different individuals display trajectories, understanding underlying relationships between lifespan disease is fundamental identifying patterns in human lifespan. A previous study explored associations age of onset diseases organ systems, prevalence escapers, percentage life free (health span), comparing them genders Catalonian population. In this retrospective study, we analyzed...

10.1007/s11357-024-01470-z article EN cc-by GeroScience 2025-01-14

Background Centenarians exhibit extreme longevity and have been postulated, by some researchers, as a model for healthy aging. The identification of the characteristics centenarians might be useful to understand process human Methods In this retrospective study, we took advantage demographic, clinical, biological, functional data deceased individuals between 2014 2020 in Guipúzcoa (Basque Country, Spain) taken from Basque Health Service electronic health records lake. Fifty derived...

10.3389/fpubh.2022.1096837 article EN cc-by Frontiers in Public Health 2023-01-25

Neuropsychiatric symptoms (NPS) are the leading cause of social burden dementia but their role is underestimated.The objective study was to validate predictive models separately identify psychotic and depressive in patients diagnosed with using clinical databases representing whole population inform decision-makers.First, we searched electronic health records 4,003 NPS. Second, machine learning (random forest) algorithms were applied build separate for symptom clusters training set (N =...

10.3233/jad-200345 article EN Journal of Alzheimer s Disease 2020-07-31

Purpose To describe a procedure for incorporating parametric functions into individual-level simulation models to sample time event when age-specific rates are available but not the individual data. Methods Using rates, regression analysis was used parametrize survival distributions (Weibull, Gompertz, log-normal, and log-logistic), select best fit using R 2 statistic, apply corresponding formula assign random times events in models. We stroke Spanish population illustrate our procedure....

10.1177/0272989x241232967 article EN Medical Decision Making 2024-02-25

Socioeconomic status (SES) and gender play a key role in mental health. The objective of this study was to assess socioeconomic health inequalities adolescents young adults using population-based registry. We conducted lifetime follow-up all residents the Basque Country between 1 30 years old (n = 609,381) as 31 December 2018. Primary care, specialized outpatient, hospital care records were searched for diagnoses. SES assessed based on household income. estimated disaggregated prevalence...

10.1016/j.rpsm.2022.07.001 article ES cc-by-nc-nd Spanish Journal of Psychiatry and Mental Health 2022-07-16

To measure 3-year care costs of breast, prostate, colorectal and lung cancers disaggregated by site clinical stage.A retrospective observational design was employed to investigate cases recorded in the Registry Basque Country between 2010 2015. Data gathered included TNM stage demographic, resource use variables. Total per patient with IV disease were calculated combining generalized linear models parametric survival analysis. Unit obtained from analytical accounting system Health...

10.1016/j.gaceta.2020.12.035 article EN cc-by-nc-nd Gaceta Sanitaria 2021-02-18

Due to population ageing and medical advances, people with advanced chronic diseases (ACD) live longer. Such patients are even more likely face either temporary or permanent reduced functional reserve, which typically further increases their healthcare resource use the burden of care on caregiver(s). Accordingly, these caregiver(s) may benefit from integrated supportive provided via digitally supported interventions. This approach maintain improve quality life, increase independence,...

10.3390/ijerph20043152 article EN International Journal of Environmental Research and Public Health 2023-02-10

To develop a framework for the management of complex health care interventions within Deming continuous improvement cycle and to test in case an integrated intervention multimorbid patients Basque Country CareWell project.Statistical analysis alone, although necessary, may not always represent practical significance intervention. Thus, ascertain true economic impact intervention, statistical results can be into budget analysis. The study consisted comprehensive approach that new provider...

10.1016/j.jval.2016.08.002 article EN cc-by-nc-nd Value in Health 2016-10-13

Abstract Background Low household income (HI), comorbidities and female sex are associated with an increased risk of dementia. The aim this study was to measure the mediating effect comorbidity HI on excess due gender in relation incidence prevalence dementia general population. Methods A retrospective observational using real-world data analysed all people over 60 who were registered Basque Health Service Gipuzkoa. measured level, Charlson index (CCI), age sex. logistic regression Poisson...

10.1186/s12877-024-04770-3 article EN cc-by BMC Geriatrics 2024-02-29

Evaluar el proceso y impacto económico de un programa integrado cuidados paliativos. Estudio transversal comparativo. Organizaciones Sanitarias Integradas Alto Deba Goierri Alto-Urola, País Vasco. Pacientes fallecidos (oncológicos no oncológicos) en 2012 (grupo control) 2015 intervención) susceptibles necesitar paliativos según la estimación mínima McNamara. Identificación pacientes con código atención primaria, uso rutas asistenciales conjuntas primaria hospitalaria e impartición cursos...

10.1016/j.aprim.2017.05.017 article ES cc-by-nc-nd Atención Primaria 2017-12-06

Breakthrough pain (BTP) has great repercussions on the quality of life, and use health resources. The scope BTP costs in cancer patients is unknown. purpose this study was to evaluate economic cost with relationship their life.A 1-month observational prospective cost-of-illness designed. recorded consumption resources drugs related a diary. current symptoms Edmonton Symptoms Assessment Scale (ESAS) life (EORTC QLQ-C30, version 3) were assessed. direct medical non-medical fixed variable...

10.1007/s40122-018-0102-0 article EN cc-by-nc Pain and Therapy 2018-07-05

The performance of a precisely controlled drilling technique is critical in the fabrication process microstructured polymer optical fibres. For creation holey preform, adequate bits with large length-to-diameter ratios provide ability machining preforms complex structures and lengths relatively short time. In this work, we analysed different techniques that can be employed for such preforms, key parameters characterising quality drilled holes, as surface rugosity, diameter deviation,...

10.3390/polym11111739 article EN Polymers 2019-10-24

The existing evidence suggests that a complete evaluation of mental health should incorporate both psychopathology and well-being indicators. However, few studies categorize European adolescents into subgroups based on such data. This study used the data symptoms behavioral disorders to explore profiles in Europe.Data collected from (N = 3767; mean age 12.4 [SD 0.9]) five countries supplied information their (personal resilience, school quality life, well-being) disorder (anxiety,...

10.1007/s00127-021-02156-z article EN cc-by Social Psychiatry and Psychiatric Epidemiology 2021-08-21

Coronavirus disease 2019 (COVID-19) vaccines are extremely effective in preventing severe disease, but their real-world cost effectiveness is still an open question. We present analysis of the cost-effectiveness and economic impact initial phase COVID-19 vaccination rollout Basque Country, Spain. To calculate costs quality-adjusted life years for entire population dynamic modelling a data were combined. Data on infection outcomes (cases, hospitalisations, intensive care unit admissions...

10.1007/s40273-023-01326-y article EN cc-by-nc PharmacoEconomics 2023-11-01

Objective The first and second rounds of the Basque programme for organised colorectal cancer screening were implemented between 2009 2014. Our objective was to measure changes in incidence, tumour, node, metastasis staging distribution metastasis-adjusted survival patients with from 2003 Method Colorectal cases (patients <70 years old) without ≥70 compared during three four-year periods: 2003–2006, 2007–2010 2011–2014 (fully phase). Cox regression, five-year relative probability death...

10.1177/0969141320921893 article EN Journal of Medical Screening 2020-05-07

Abstract Background The LipiDiDiet trial showed that Souvenaid, a medical food, might delay progression to dementia in prodromal Alzheimer’s disease (AD). objective of this study was assess the cost-utility Souvenaid compared placebo patients with AD under conditions applied trial. Methods A discrete event simulation model developed based on and literature review from societal perspective considering direct indirect costs. For both intervention control groups, patient trajectories terms...

10.1186/s13195-020-00737-9 article EN cc-by Alzheimer s Research & Therapy 2020-12-01

As mental health in adulthood is related to status during adolescence, school-based interventions have been proposed improve resilience. The objective of this study was build a simulation model representing the natural history disorders childhood, adolescence and youth estimate cost-effectiveness UPRIGHT intervention promoting resilience adolescence.We built discrete event fed with real-world data (cumulative incidence disaggregated into eight clusters) from Basque Health Service database...

10.1186/s12888-023-04665-4 article EN cc-by BMC Psychiatry 2023-03-17
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