C. Lions

ORCID: 0000-0003-0712-2572
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About
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Research Areas
  • HIV/AIDS Research and Interventions
  • HIV, Drug Use, Sexual Risk
  • Hepatitis C virus research
  • Cannabis and Cannabinoid Research
  • HIV-related health complications and treatments
  • Substance Abuse Treatment and Outcomes
  • HIV/AIDS drug development and treatment
  • Opioid Use Disorder Treatment
  • Cardiac Imaging and Diagnostics
  • Liver Disease Diagnosis and Treatment
  • Advanced MRI Techniques and Applications
  • Viral-associated cancers and disorders
  • HIV Research and Treatment
  • Antibiotic Use and Resistance
  • Lymphoma Diagnosis and Treatment
  • Alcohol Consumption and Health Effects
  • Prenatal Substance Exposure Effects
  • Hepatitis B Virus Studies
  • Patient Satisfaction in Healthcare
  • Advanced X-ray and CT Imaging
  • Acute Ischemic Stroke Management
  • Renal and Vascular Pathologies
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Bipolar Disorder and Treatment
  • Endometriosis Research and Treatment

University of Crete
2025

Inserm
2009-2022

Aix-Marseille Université
2012-2022

Institut de Recherche pour le Développement
2009-2022

Economic & Social Sciences, Health Systems & Medical Informatics
2010-2022

Hôpital Sainte-Marguerite
2017-2022

Institut Pasteur
2021

Université Toulouse III - Paul Sabatier
2020

Centre Hospitalier Universitaire de Rennes
2019

ARPE PACA
2009-2017

Depressive disorders have been linked to health risk-related behaviours (HRBs) considered separately. Our objective was study whether depression is associated with the co-occurrence of HRBs in adults.A sample 17 355 subjects aged > or =18 years, derived from 2002-03 cross-sectional Decennial Health Survey; probable assessed CES-D scale. A cluster analysis various (tobacco use, alcohol binge drinking, physical inactivity, certain eating habits) used their co-occurrence. Multiple regressions...

10.1093/eurpub/ckp057 article EN European Journal of Public Health 2009-04-29

Abstract Aims To study the effectiveness of an educational intervention on risks associated with drug injection, comparing primary [unsafe HIV–hepatitis C virus (HCV) practices] and secondary (local complications at injecting site) end‐points in harm reduction (HR) programmes offering this versus HR not it. Design This non‐random clustered was conducted nine groups (programmes intervention) eight control it). Each participant followed‐up through a telephone interview enrolment 6 12 months....

10.1111/add.13089 article EN Addiction 2015-08-02

Although methadone maintenance treatment (MMT) is recognized as the of reference for opioid dependence, little information available regarding dynamic adherence to and its determinants. With data from Methaville trial we investigated evolution non-adherence effect pre-treatment in-treatment factors on longterm methadone.We selected 145 patients study at 3, 6 12 months (M3, M6 M12, respectively) using a multidimensional questionnaire 3-level variable "adherent"/"non adherent"/"highly...

10.2174/13816128113199990623 article EN Current Pharmaceutical Design 2014-03-14

Identifying risk factors associated with overweight and obesity in HIV-infected patients. A cross-sectional study analyzing data from patients attending an HIV outpatient unit. Overweight was defined as body mass index (BMI) ≥25 kg/m2; <30 kg/m2, ≥30 kg/m2. Patients' characteristics contemporary to BMI assessment were collected. Multivariate logistic regression identified overweight/obesity. Eight hundred sixty-two patients, median age 51 years, 21.5 years of infection follow-up, 585 (68%)...

10.1097/md.0000000000010956 article EN cc-by-nc Medicine 2018-06-01

Background Nursing home (NH) residents are frequently treated with antibiotics for urinary tract infections (UTIs), often due to overdiagnosis. The aim of this study was evaluate the proportion potentially unnecessary antibiotic use suspected UTIs in NHs across eight European countries.

10.1080/14787210.2025.2456860 article EN cc-by-nc-nd Expert Review of Anti-infective Therapy 2025-01-20

Objective Methadone coverage is poor in many countries due part to methadone induction being possible only specialized care (SC). This multicenter pragmatic trial compared the effectiveness of treatment between two models: primary (PC) and SC. Methods In this study, registered at ClinicalTrials.Gov (NCT00657397), opioid-dependent individuals not on for least one month or receiving buprenorphine but needing switch were randomly assigned start PC (N = 155) SC 66) 10 sites France. Visits...

10.1371/journal.pone.0112328 article EN cc-by PLoS ONE 2014-11-13

Cocaine use is frequent in patients receiving methadone maintenance treatment (MMT) and can jeopardize their response. Identifying clinical predictors of cocaine during potentially improve management. We used longitudinal data from the ANRS Methaville trial both to describe self-reported occasional regular MMT identify predictors. selected 183 who had on (or crack) at months 0 (M0), M6, and/or M12, accounting for 483 visits. The outcome was "cocaine use" three categories: "no," "occasional,"...

10.1186/s12954-016-0100-7 article EN cc-by Harm Reduction Journal 2016-04-05

Abstract Background Integrase strand transfer inhibitors (INSTIs) are increasingly used in patients living with HIV due to their safety, effectiveness and high genetic barrier. However, an association weight gain has recently been suggested several cases of diabetes mellitus have reported raltegravir dolutegravir. The long-time metabolic impact these recent molecules remains unclear. Objectives To assess if INSTI as a third agent is statistically associated new-onset compared NNRTI or PI....

10.1093/jac/dkaa330 article EN Journal of Antimicrobial Chemotherapy 2020-07-06

Cancer risk is higher in people living with HIV (PLWH) compared the general population, and cancers related to age are expected be most prevalent.We determined spectrum incidence rates of AIDS-defining (ADC) non-AIDS-defining (NADC) lung, Hodgkin lymphoma (HL), head neck (HNC), colon-rectum, anal, liver, breast, prostate, urinary bladder between January 2010 December 2015 French Dat'AIDS cohort. Incidence were calculated by year using χ2 test for linear trend. Standardized ratios [SIR (95%...

10.1158/1055-9965.epi-20-1045 article EN Cancer Epidemiology Biomarkers & Prevention 2020-12-11

Prisoners constitute a high-risk population, particularly for infectious diseases. The aim of this study was to estimate the level risk in prisons five different European countries by measuring what extent prison system adheres WHO/UNODC recommendations. Following methodology used previous French survey, postal/electronic questionnaire sent all Austria, Belgium, Denmark and Italy collect data on availability several recommended HIV-HCV prevention interventions HBV vaccination prisoners. A...

10.1186/s12889-015-2421-y article EN cc-by BMC Public Health 2015-10-27

Coxiella burnetii vascular infections continue to be very severe diseases and no guidelines exist about their prevention. In terms of treatment, the benefit surgical removal infected tissues has been suggested by 1 retrospective study. We present a case C abdominal aortic graft infection for which we observed dramatic clinical biological recovery after surgery. thus performed cohort study evaluate impact surgery on survival serological outcome patients with Q fever diagnosed in our center....

10.1097/md.0000000000002810 article EN cc-by-nc Medicine 2016-03-01

Background. Diabetes and insulin resistance (IR) is common in human immunodeficiency virus–hepatitis C virus (HIV–HCV)-coinfected patients, a population also concerned with elevated cannabis use. Cannabis has been associated reduced IR risk some population-based surveys. We determined whether use was consistently HEPAVIH, French nationwide cohort of HIV–HCV-coinfected patients. Methods. HEPAVIH medical sociobehavioral data were collected (using annual self-administered questionnaires). used...

10.1093/cid/civ217 article EN Clinical Infectious Diseases 2015-03-16

Abstract Introduction and Aims Despite cannabis use being very common in patients co‐infected with HIV hepatitis C virus (HCV), its effect on these patients' immune systems remains undocumented. Documenting the potential of immunological markers would help caregivers make more targeted health recommendations to patients. We performed a longitudinal analysis relationship between peripheral blood CD4 T‐cell measures receiving antiretroviral therapy. Design Methods Cannabis was assessed using...

10.1111/dar.12398 article EN Drug and Alcohol Review 2016-04-13

10.1016/j.jinf.2017.05.008 article EN Journal of Infection 2017-06-02

10.1007/s10096-013-1828-6 article EN European Journal of Clinical Microbiology & Infectious Diseases 2013-01-29

Kaposi sarcoma is still observed among people living with HIV (PLHIV) including those on ART undetectable viral load (HIV-VL). We aimed to assess incidence and trends between 2010 2015 in France highlight associated factors.Retrospective study using longitudinal data from the Dat'AIDS cohort 44 642 PLWH. For assessment, cases occurring within 30 days of enrollment were excluded.Demographic, immunological, therapeutic characteristics collected at time diagnosis or last visit for patients...

10.1097/qad.0000000000002450 article EN AIDS 2019-11-25

10.1007/s10096-012-1743-2 article EN European Journal of Clinical Microbiology & Infectious Diseases 2012-09-15
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