- Face Recognition and Perception
- Neuroscience and Neural Engineering
- Neural dynamics and brain function
- stochastic dynamics and bifurcation
- Neural Networks and Applications
- Remote Sensing and Land Use
- Glioma Diagnosis and Treatment
- Memory and Neural Mechanisms
- Advanced MRI Techniques and Applications
- Olfactory and Sensory Function Studies
- Advanced Memory and Neural Computing
- melanin and skin pigmentation
- Neuroscience and Neuropharmacology Research
- Gaze Tracking and Assistive Technology
- Visual Attention and Saliency Detection
- Primate Behavior and Ecology
- Anesthesia and Neurotoxicity Research
- Technology and Human Factors in Education and Health
- Neurological disorders and treatments
Western University
2018-2025
Robarts Clinical Trials
2024
Abstract Cells selectively activated by a particular view of an environment have been found in the primate hippocampus (HPC). Whether cells are present other brain areas, and how selectivity interacts with variables such as object features place remain unclear. Here, we explore these issues recording responses neurons HPC lateral prefrontal cortex (LPFC) rhesus macaques performing task which they learn new context‐object associations while navigating virtual using joystick. We measured...
Abstract Recordings of cortical neurons isolated from brain slices and dissociated their networks, display intrinsic spike frequency adaptation (I-SFA) to a constant current input. Interestingly, extracellular recordings in behaving subjects also show extrinsic-SFA (E-SFA) response sustained visual stimulation. Because are networks slice recordings, it is challenging infer how I-SFA contributes E-SFA interconnected brains during behavior. To investigate this, we recorded responses macaque...
Accurate targeting of brain structures for in-vivo electrophysiological recordings is essential basic as well clinical neuroscience research. Although methodologies precise and recording from the cortical surface are abundant, such protocols scarce deep structures.We have incorporated stable fiducial markers within a custom cranial cap improved image-guided neuronavigation subcortical in macaque monkeys. Anchor bolt chambers allowed minimally invasive entrance into chronic recordings. A...
Detecting where other individuals are allocating their gaze is crucial for humans and primates when assessing intention to initiate contact. Previous literature has shown the different contributions of head orientation contact discrimination in center periphery visual field. However, best our knowledge, all previous studies have assessed this using static images. In current study we evaluated contribution eye by 3D face models test participants a 3-forced choice task ranging up 18° angle...
Perceived gaze direction results from a mechanism that takes into account the orientation of eyes and head relative to observer (Todorovic 2006). Studies using two-dimensional images have shown influence perceived (Wollaston illusion; see Langton 2000). However, this effect has not been studied 3D images; it is possible cues modulate interactions between direction. We clarify issue by virtual reality displays digitized faces while manipulating eye orientation. also white sclera on replacing...
Abstract Precise targeting of deep brain structures in humans and large animal models has been a challenge for neuroscientists. Conventional protocols used typically require access chambers which are prone to infection involve assembly implantation complex microdrives semi-chronic applications. Here we present methodology improving subcortical animals such as macaque monkeys, using image guided neuronavigation. Design custom cranial caps allowed incorporation stable fiducial markers,...