A5043302161- Cutaneous Melanoma Detection and Management
- Nonmelanoma Skin Cancer Studies
- Cutaneous lymphoproliferative disorders research
- Cancer and Skin Lesions
- Skin Protection and Aging
- Polyomavirus and related diseases
- AI in cancer detection
- Digital Imaging in Medicine
- Viral-associated cancers and disorders
- Melanoma and MAPK Pathways
- Reconstructive Facial Surgery Techniques
- Allergic Rhinitis and Sensitization
- Medicine and Dermatology Studies History
- Cancer Genomics and Diagnostics
- Lymphoma Diagnosis and Treatment
- Social Media in Health Education
- Health Systems, Economic Evaluations, Quality of Life
- Dermatologic Treatments and Research
- Indoor Air Quality and Microbial Exposure
- Radiomics and Machine Learning in Medical Imaging
- Cytomegalovirus and herpesvirus research
- Infectious Diseases and Mycology
- Cell Image Analysis Techniques
- Medical Malpractice and Liability Issues
Skåne University Hospital
2018-2025
Lund University
2019-2025
Monash University
2024
Alfred Health
2024
Karolinska Institutet
2009-2012
Background. The risk of cutaneous squamous cell carcinoma (CSCC) is found to be substantially increased after organ transplantation. association with specific immunosuppressive regimens has been previously investigated, but results are not concordant. We aimed clarify the relationship between separate drugs, drug load, timing and post-transplant CSCC. Methods. A population-based nested case-control study was performed in Swedish transplantation cohort (n = 5931). All patients who developed...
Basal cell carcinoma (BCC) is the most common skin cancer. Incidence largely unknown because of incomplete, or lack of, registration in countries.To assess current incidence rates and recent trends for BCC Swedish population.Patient- tumour-related features all histologically confirmed tumours diagnosed Sweden from 2004 to 2017 were extracted population-based Registry. standardized 2013 European Standard Population analysed using Poisson regression models.The age-standardized person-based...
The recommended treatment for cutaneous squamous cell carcinoma is surgical excision. An initial punch biopsy often performed as an aid to diagnosis. A retrospective registry-based study was assess histopathological concordance of and subsequent Analysis 737 biopsies matched excisions performed. In total, 493 (67%) lesions were confirmed invasive on excision, 76% when excluding "scar" a final Tumour diameter > 20mm highly predictive (positive value 91.1%). Tumours the scalp significantly...
Background: Teledermoscopy (TDS) emerges as an efficient tool for diagnosing skin lesions. In Sweden, double reading is the standard of care, but risk factors misdiagnosis or mismanagement using single reader evaluations (SRE) are not well-studied. This study aimed to assess accuracy SRE compared with gold in TDS. Methods: retrospective cohort involved 1,997 TDS referrals sent from general practitioners dermatologists Stockholm, selected based on dermoscopic diagnoses. All underwent (DRE)....
ABSTRACT Background Several widely used drugs have photosensitizing properties, and much research has been conducted to find associations between their use the risk of developing cutaneous malignant melanoma (cM), basal cell carcinoma (BCC) or squamous (cSCC), often with conflicting results. Objective To assess whether commonly prescribed increases skin cancer risk. Methods Analyses were performed using a large cohort women, prospectively collected information on phenotypic traits sun...
Increased cancer risks are well documented in adult organ transplant recipients. However, the spectrum of malignancies and risk pediatric population less described. We identified all solid transplanted patients aged <18 Sweden between 1970-2007 (n = 536) National Patient Register linked to Cancer Register. Nationwide rates were used calculate standardized incidence rate ratios 95% CI estimating association during maximum 36 years follow-up. Nearly 7% recipients developed a premalignant or...
Organ transplantation increases risk of non-Hodgkin lymphoma (NHL), but long-term and time trends have seldom been evaluated. Immunosuppressive drug load is an important determinant, the details are unclear. We studied NHL in a nationwide Swedish cohort 11 081 graft recipients transplanted 1970–2008. Relative risks (RRs) were estimated within versus general population by age, sex, follow-up calendar period. was also assessed cumulative average doses immunosuppressive treatments nested...
Abstract Background/Objectives Artificial intelligence (AI) holds remarkable potential to improve care delivery in dermatology. End users (health professionals and general public) of AI‐based Software as Medical Devices (SaMD) require relevant labelling information ensure that these devices can be used appropriately. Currently, there are no clear minimum requirements for dermatology SaMDs. Methods Common recommendations SaMD identified a recent literature review were evaluated by an...
Chronic sun-damaged (CSD) melanoma represents 10%-20% of cutaneous melanomas and is characterized by infrequent BRAF V600E mutations high mutational load. However, the order genetic events or extent intra-tumor heterogeneity (ITH) in CSDhigh still unknown. Ultra-deep targeted sequencing 40 cancer-associated genes was performed 72 situ invasive CMM, including 23 cases. In addition, we whole exome RNA on multiple regions primary tumor in-transit metastases from one patient. We found no...
Diagnosing invasive cutaneous melanoma (CM) can be challenging due to subjectivity in distinguishing equivocal nevi, situ and thin CMs. The underlying molecular mechanisms of progression from nevus must better understood. Identifying biomarkers for treatment response, diagnostics prognostics is crucial. Using biomedical data biobanks population-based healthcare data, translational research improve patient care by implementing evidence-based findings. BioMEL biobank a prospective,...
Acral melanoma is a clinical subtype of with high mortality, on which research limited in scope. This study aimed to assess incidence trends and melanoma-specific survival rates for acral the Swedish population from 1990 2020.This cross-sectional included patients an diagnosis 2020 nationwide, population-based Melanoma Registry. Analyses were adjusted age, sex, histopathological subtype, tumour thickness. Clinicopathological features compared between diagnostic periods: 1990-1999, 2000-2009,...
Skin cancer incidence is rapidly increasing. The main risk factor, sun exposure, can be modified. Informational campaigns effective in raising skin awareness and target the high-risk population. Still, exposure habits people at high of are not well-known.To investigate if how differ between low-risk individuals.During Swedish Euromelanoma campaign 2018, questionnaires were collected containing information regarding factors for cancer. Data on 4,141 participants was used to association...
Abstract Purpose To investigate factors related to omitted total body skin examination (TBSE) in cancer diagnostics while managing patients using teledermoscopy (TDS) Swedish primary care. Methods 4,987 TDS referrals from care centers were analyzed identify associated with failing perform TBSE. Data collected included age, gender of patient and physician, reason for a visit. Logistic regression was used test the association between variables risk complete Results The TBSE is higher older...
Recipients of solid organ transplants are at a markedly increased risk cutaneous squamous cell carcinoma (SCC). We investigated potential associations between post-transplant infections, HLA type, and other transplant-related factors SCC, taking immuno-suppressive treatment into account. A population-based case-control study was conducted. All patients who developed SCC during follow-up (1970-1997) were eligible as cases (n = 207). Controls 189) individually matched to the on age calendar...
Mohs micrographic surgery (MMS) is a precise, tissue-sparing surgical technique that offers superior cure rates compared to traditional excision. However, the degree of difficulty MMS depends on many variables, and consequently, number stages required for each case quite unpredictable.To identify risk factors complicated MMS, defined as requiring ≥3 stages.In cohort study design, data were prospectively collected from 612 patients underwent basal cell carcinoma (BCC) at Department...
Basal cell carcinoma (BCC) is a common skin cancer type and affected individuals are known to be at risk of developing multiple consecutive tumours. Research into BCC multiplicity has, thus far, been challenging, due lack national registration. This registry-based cohort study aimed analyse the occurrence BCCs in Sweden, factors for subsequent primary BCCs. Data regarding all histopathologically verified, tumours Sweden from 2004 2017 was extracted Swedish Registry. Risk relation...
The rising incidence of melanoma and the high number benign lesions excised due to diagnostic uncertainty highlight need for effective patient triage. This study assesses safety accuracy teledermoscopic triage on a high-prevalence case set with pre-triaged, challenging, melanoma-suspicious lesions.
Skin cancer is a prevalent and clinically significant condition, with early accurate diagnosis being crucial for improved patient outcomes. Dermoscopy artificial intelligence (AI) hold promise in enhancing diagnostic accuracy. However, the impact of image quality, particularly high dynamic range (HDR) conversion smartphone images, on performance remains poorly understood.
Abstract Introduction Teledermatoscopy (TDS) has proven to be effective and reliable for diagnosis of skin malignancies. The factors that determine the success implementation TDS are largely unknown. Objectives To investigate barriers in primary health care (PHC) at center individual level. Methods Following introduction TDS, cross-sectional quantitative data free text comments were collected by surveys sent PHC centers PCH practitioners. Successful was defined as regularly cases level...