A5100403089- MicroRNA in disease regulation
- Cancer Mechanisms and Therapy
- Circular RNAs in diseases
- RNA Research and Splicing
- Cancer Genomics and Diagnostics
- Cancer, Hypoxia, and Metabolism
- Electrospun Nanofibers in Biomedical Applications
- Cancer-related molecular mechanisms research
- Bone Tissue Engineering Materials
- CAR-T cell therapy research
- RNA modifications and cancer
- Lung Cancer Research Studies
- Lung Cancer Treatments and Mutations
- Adenosine and Purinergic Signaling
- Cancer-related gene regulation
- 3D Printing in Biomedical Research
- Phagocytosis and Immune Regulation
- Tissue Engineering and Regenerative Medicine
- Immunotherapy and Immune Responses
- Mycobacterium research and diagnosis
- Molecular Biology Techniques and Applications
Soochow University
2014-2024
First Affiliated Hospital of Soochow University
2015-2024
Jiangsu University
2023
Affiliated Hospital of Jiangsu University
2023
Peking University
2019
Nanjing Medical University
2014
// Lin Wang 1,* , Zhu-mei Shi 1,2,* Cheng-fei Jiang Xue Liu 1 Qiu-dan Chen Xu Qian Dong-mei Li Xin Ge Xie-feng 2 Ling-Zhi 3 Yong-ping You Ning and Bing-Hua 1,3 State Key Lab of Reproductive Medicine, Department Pathology, Nanjing Medical University, Nanjing, China Neurosurgery, The First Affiliated Hospital Anatomy Cell Biology, Thomas Jefferson Philadelphia, USA * These authors contributed equally to this work Correspondence: Jiang, email: Liu, Keywords : miR-143, N-RAS, tumor growth,...
A two-dimensional (2D) cell culture-based model is widely applied to study tumorigenic mechanisms and drug screening. However, it cannot authentically simulate the three-dimensional (3D) microenvironment of solid tumors provide reliable predictable data in response vivo , thus leading research illusions failure In this study, honeycomb-like gelatin methacryloyl (GelMA) hydrogel microspheres are developed by synchronous photocrosslinking microfluidic technique construct a 3D osteosarcoma. The...
Niclosamide is a traditional anti-tapeworm drug that exhibits potent anti-cancer activity. Our previous study showed niclosamide induces cell cycle arrest in G1 phase. Nevertheless, the underlying mechanism remains unknown. The following investigated molecular through which induced head and neck squamous carcinoma (HNSCC) lines. effect of on human HNSCC line WSU-HN6 CNE-2Z were analyzed using IncuCyte ZOOMTM assay, flow cytometry (FCM), real-time PCR western blot. Luciferase assay was...
Patients bearing liver metastasis of pancreatic adeno carcinoma (PDAC) suffer from poor prognosis due to its short duration and high mortality. Complex tumor microenvironment (TME) exists in metastatic niches, tumor-associated macrophages (TAMs) have play vital roles generation outgrowth. We discovered that M2 type TAM-derived SEMA5A could bind cell-expressed receptor PLXNB3 promote cell proliferation utilized samples PDAC patients, intrasplenic injection mouse models, Kras G12D/Trp53...
The detection of somatic epidermal growth factor receptor (EGFR) mutations is valuable when an appropriate therapy, either EGFR-tyrosine kinase inhibitor (TKI) therapy or chemotherapy, for patients with advanced non-small cell lung cancer (NSCLC) needs to be selected. Although it well‑understood that EGFR mutation significant the decision‑making regarding treatment, no consensus on methodology should most preferebale detecting in clinical practice has been reached. presence false positives...
Nucleostemin, nucleolar guanosine triphosphate (GTP)-binding protein 3, is a member of the MMR1/HSR1 GTP-binding family. The important roles nucleostemin in self-renewal, cell cycle regulation, apoptosis, and proliferation various cancer types as been shown. Nevertheless, its expression potential functions human glioma still unclear. In present study, we demonstrated that up-regulation was tightly related to poor 5-year-survival ratios. serum-starved re-feeding models U251 U373MG, observed...
<p>Table S1: Clinical and molecular characteristics of the glioma cases profiled by scRNA-seq.</p>