- Birth, Development, and Health
- Pregnancy and preeclampsia studies
- Colorectal Cancer Treatments and Studies
- Pregnancy-related medical research
- Liver Disease Diagnosis and Treatment
- Maternal and Perinatal Health Interventions
- Growth Hormone and Insulin-like Growth Factors
- Lung Cancer Research Studies
- Lung Cancer Treatments and Mutations
- Medical Imaging and Pathology Studies
- Maternal and fetal healthcare
- Pneumocystis jirovecii pneumonia detection and treatment
- Lipid metabolism and disorders
- Ectopic Pregnancy Diagnosis and Management
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pleural and Pulmonary Diseases
- Neonatal Respiratory Health Research
- Antifungal resistance and susceptibility
- Aquatic Ecosystems and Phytoplankton Dynamics
- Protease and Inhibitor Mechanisms
- Pancreatitis Pathology and Treatment
- Assisted Reproductive Technology and Twin Pregnancy
- Climate Change and Health Impacts
- Colorectal Cancer Surgical Treatments
- Cancer Genomics and Diagnostics
Soochow University
2008-2023
First Affiliated Hospital of Soochow University
2008-2023
Suzhou Municipal Hospital
2018-2023
Nanjing Medical University
2017-2023
Second Affiliated Hospital of Soochow University
2021
New York Medical College
2004
The detection of somatic epidermal growth factor receptor (EGFR) mutations is valuable when an appropriate therapy, either EGFR-tyrosine kinase inhibitor (TKI) therapy or chemotherapy, for patients with advanced non-small cell lung cancer (NSCLC) needs to be selected. Although it well‑understood that EGFR mutation significant the decision‑making regarding treatment, no consensus on methodology should most preferebale detecting in clinical practice has been reached. presence false positives...
To investigate the expression of insulin-like growth factor binding protein-3(IGFBP-3) in HELLP syndrome and its possible role pathogenesis this disease.1) 87 subjects were enrolled, including 29 patients with syndrome, pre-eclampsia (PE), healthy gravidae as control. The levels IGFBP-3, IGF-1, TGF-β1, VEGF maternal umbilical blood them detected using ELISA. Correlation analysis was used to observe correlation between IGFBP-3 IGF-1/TGF-β1/VEGF blood, well that serum clinical diagnostic...
New indicators in evaluation of hemolysis, elevated liver enzymes, and low platelet syndrome: A case-control study
To investigate the effectiveness of high-dose glucocorticoids on hemolysis, elevating liver enzymes, and reducing platelets (HELLP) syndrome.A total 151 patients with HELLP syndrome were analyzed divided into two groups. Six subgroups treatment control groups three grades in accordance American Mississippi Diagnostic Criteria.There no differences general characteristics patients, primipara rate, minimum platelet recovery time, postpartum hemorrhage volume, cumulative average maternal damage,...
BACKGROUND:Placenta accreta spectrum (PAS) includes placenta increta, percreta, and accreta. PAS is due to abnormal decidualization can lead severe maternal hemorrhage occurs in up 3% of women with central placental previa (CPP). This study from a single center aimed compare the magnetic resonance imaging (MRI) changes lower uterine segment pregnant CPP, without PAS. MATERIAL AND METHODS:This retrospective 90 66 All participants were confirmed have CPP by MRI. Eight MRI parameters assessed...
Background: To evaluate the efficacy and safety of carbetocin compared with oxytocin for prevention postpartum hemorrhage (PPH) after elective cesarean section in Chinese high risk women. Methods: This was a single-center, prospective, randomized, open-label, controlled trial recruiting 852 pregnant women one or more PPH factors between April 2017 August 2019. Pregnant woman who scheduled an were randomly assigned to receive PPH. The primary endpoint proportion additional uterotonics....
To screen the differential expression cytokines (DECs) in hemolysis, elevated liver enzymes, and low platelet (HELLP) syndrome, establish its spectra, provide clues for diagnosis pathogenic mechanism researches. Sera from four HELLP syndrome patients healthy controls were detected by proteome microarray. Then analysis of Gene Ontology (GO) enrichment, Kyoto Encyclopedia Genes Genomes (KEGG) pathway, protein–protein interaction (PPI) network performed possible hub proteins selected out,...
We present an unusual case of extramedullary acute myelogenous leukemia (AML) presenting as bilateral testicular masses. The patient subsequently developed diffuse skin lesions and bone marrow involvement. Although he had only a partial response to intensive chemotherapy, the obtained complete remission after non-myeloablative allogeneic transplantation.
Objective To study the pathological morphologic characteristics of invasive pituitary tumors and affect expression Ki-67 MMP-9 to tumor invasion.Methods Analyzing 130 cases specimens from January 2003 december 2011,which divided into two groups according invasion,observe through light electron microscope via immunohistochemistry (IHC).Results The difference was statistically significant(P < 0.05) between group noninvasive in incidence rate characteristics,such as high nuclearcytoplasmic...
Abstract Objective To investigate the expression of insulin-like growth factor binding protein-3(IGFBP-3) in HELLP syndrome and its possible role pathogenesis this disease. Methods 1) 87 subjects were enrolled, including 29 patients with syndrome, simple pre-eclampsia(PE), healthy gravidae as control. The IGFBP-3, IGF-1, TGF-β1, VEGF maternal umbilical blood them detected using ELISA. Correlation analysis was used to observe correlation between IGFBP-3 IGF-1/TGF-β1/VEGF andumbilical blood,...