A5102872489- Immune Response and Inflammation
- Polyamine Metabolism and Applications
- Respiratory Support and Mechanisms
- Regulation of Appetite and Obesity
- Sepsis Diagnosis and Treatment
- Kawasaki Disease and Coronary Complications
- Plant Stress Responses and Tolerance
- Cardiac Arrest and Resuscitation
- Inflammation biomarkers and pathways
- Functional Brain Connectivity Studies
- Vasculitis and related conditions
- Pancreatic function and diabetes
- Cholesterol and Lipid Metabolism
- Advanced MRI Techniques and Applications
- NF-κB Signaling Pathways
- Allelopathy and phytotoxic interactions
- Mechanisms of cancer metastasis
- Phytochemistry and biological activity of medicinal plants
- Monoclonal and Polyclonal Antibodies Research
- Adipose Tissue and Metabolism
- Blood Coagulation and Thrombosis Mechanisms
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- RNA Interference and Gene Delivery
- FOXO transcription factor regulation
Liaocheng People's Hospital
2016-2025
Chongqing Medical University
2012-2017
Children's Hospital of Chongqing Medical University
2017
Nanjing Normal University
2011-2014
Shenzhen Children's Hospital
2012-2013
Jilin University
2011-2012
The objective of this study was to evaluate the immunomodulatory effects cinobufagin (CBG) isolated from Chan Su (Venenum Bufonis) in vitro. In paper, our results show that CBG significantly stimulated cell proliferation splenocytes and peritoneal macrophages (PMΦ) markedly enhanced phagocytic activation PMΦ. also increased CD4(+)CD8(+) double-positive T-cell populations percentage S-phase cells splenic lymphocytes. levels several Th1 cytokines, including interferon-γ tumor necrosis...
To investigate the role of miR-146 and its possible relationship with MALAT1 in LPS-induced inflammation human microvascular endothelial cells (HMECs), HMEC-1 were treated LPS to construct an inflammatory injury cell model, viability, TNF-α IL-6 secretion expression levels VCAM-1, SELE ICAM-1 analysed as markers injury. The regulation mechanisms interacted downstream NF-κB signalling also verified by dual-luciferase assay knockdown technology. significantly decreased increased up-regulated...
In this paper, the convolution sum ∑ i+25j=n σ(i)σ(j) is evaluated for all n ∈ ℕ based on some identities due to Berndt, Lemire and Williams.
BACKGROUND Golgi phosphoprotein 3 (GOLPH3) has been reported to be involved in the development of several human cancers. Our previous study showed that GOLPH3 expression glioma tissues was related severity malignancy cancer. However, mechanism by which affects cell apoptosis is largely unknown. The present designed explore possible apoptosis. MATERIAL AND METHODS To analyze biological role cells, we used small interference RNA cells. cells detected flow cytometry. level and NDRG1 protein...
Background Acute respiratory distress syndrome (ARDS) is a severe condition characterized by lung stiffness and compromised gas exchange, often requiring mechanical ventilation for treatment. In addition to its clinical significance, understanding the publication trends research patterns in mechanics related ARDS can provide insights into evolution of this field from bibliometric perspective, aiding strategic planning resource allocation future endeavors. Objective This study aimed explore...
Objective To investigate the effects of intravenous immunoglobulin (IVIG) on expression FcγR Ⅱ b and Toll-like receptor 4 (TLR4) in children with Kawasaki disease (KD).Methods 25 KD 15 healthy controls were enrolled this study.The levels TLR4 monocytes assessed by flow cytometry.Real-time PCR was performed to detect transcription b,TLR4 signaling molecules(MyD88,TRAF-6,TAK1) cytokines(IL-1β,IL-6,TNF-α) monocytes.The concentrations TNF-α plasma determined enzyme-linked immunosorbent assay...
Objective To investigate the changes and roles of Fc gamma receptors (FcγR) expressed on monocytes in immune pathogenesis Henoch-Schonlein purpura(HSP).Methods Thirty children HSP 15 health controls were enrolled this study.The expressions FcγR Ⅰ FcγRⅢ determined by flow cytometry,and real-time PCR was performed to detect transcription levels Ⅱ a,FcγR b,cytokines(IL-1 β,IL-6,TNF-α,IFN-α),chemokine(IP-10,RANTES,iNOS),and BLyS/April isolated microbeads.The plasma concentrations IL-4,IL-10...
Objectives To explore the characteristic of different subtypes depression on prefrontal lobe and hippocampus by proton magnetic resonance spectroscopy (1H-MRS), its relationship. Methods 46 patients depression, which were met with third edition Chinese Classification Mental Disorders (CCMD-Ⅲ) since December 2010 to March 2012 from Diseases Prevention Treatment Institute, examined at multi-voxel 1H-MRS. They divided into male (n=25) female (n=21), early-onset subtype (n=26) late-onset...
With the deepening of study on immune mechanism sepsis, it is now generally believed that host responses to sepsis involve multiple sequential or concurrent processes, including both excessive inflammation and immunosuppression. The main dysfunction, abnormalities in innate adaptive responses. Based recent we explore changes body′s response from perspective immunity immunity. Key words: Sepsis; Innate immunity; A daptive immunity; Inflammation