A5066743724- Reproductive Biology and Fertility
- Cancer-related molecular mechanisms research
- Ovarian function and disorders
- Maritime Ports and Logistics
- Antimicrobial Peptides and Activities
- Vehicle Routing Optimization Methods
- Circular RNAs in diseases
- Metaheuristic Optimization Algorithms Research
- Endometrial and Cervical Cancer Treatments
- MicroRNA in disease regulation
- Ovarian cancer diagnosis and treatment
- Reproductive System and Pregnancy
- Biochemical and Structural Characterization
- Advanced Manufacturing and Logistics Optimization
- Cancer, Lipids, and Metabolism
- Cancer-related gene regulation
- Sperm and Testicular Function
- Plant Stress Responses and Tolerance
- Electrocatalysts for Energy Conversion
- RNA modifications and cancer
- Endometriosis Research and Treatment
- Nutrition, Genetics, and Disease
- Advanced battery technologies research
- Kruppel-like factors research
- Genetic Syndromes and Imprinting
Lanzhou University
2016-2025
First Hospital of Lanzhou University
2016-2025
Wuhan University of Science and Technology
2016-2024
Gansu University of Traditional Chinese Medicine
2023
Zhejiang Normal University
2019
Chinese Academy of Medical Sciences & Peking Union Medical College
2014-2016
Wuhan University of Technology
2009-2015
China University of Geosciences (Beijing)
2014
Central South University
2014
Urumqi General Hospital of PLA
2012
ABSTRACT Angiogenesis plays crucial roles in various physiological processes including wound healing and tissue repair. It requires a tight interaction between endothelial cells their surrounding environment. Mesenchymal stem (MSCs), one of the non-endothelial cell types present perivascular environment, have been shown to secret exosomes modulate intercellular communications MSCs target cells. In this study, we initially isolated secreted by human adipose-derived (adMSC-Exo) examined...
Bone and fat cells share a common progenitor, stromal/mesenchymal stem (MSCs), that can differentiate into osteoblasts or adipocytes. Osteogenesis adipogenesis of MSCs maintain homeostasis under physiological conditions. The disruption this leads to bone-related metabolic diseases. For instance, reduction in bone formation, which is usually accompanied by an increase marrow adipogenesis, occurs with aging, immobility, osteoporosis. Thus, it crucial gain understanding how osteogenic...
To meet the crucial demand of regenerative Zn–air (ZA) batteries, low cost, highly efficient, and durable electrocatalysts for oxygen evolution reaction (OER) reduction (ORR) are needed to replace noble metal. Herein, porous NiO/NiCo2O4 nanofibers with superior electrocatalytic performance synthesized by a facile electrospinning strategy precursor transition metal salts in nonstoichiometric ratio, which confers heterostructured abundant interface-related active sites electronic transmission...
Promoting the initially deficient but economical catalysts to high-performing competitors is important for developing superior catalysts. Unlike traditional nano-morphology construction methods, this work focuses on intrinsic catalytic activity enhancement via heteroatom doping strategies induce lattice distortion and optimize spin-dependent orbital interaction alter charge transfer between reactants. Experimentally, a series of different concentrations fluorine-doped lanthanum cobaltate (Fx...
Magnetic hyperthermia is one of the most promising techniques for treating gynecological cancer, where magnetite (Fe3O4) common nanomaterial used as a magnetic agent. Here, we demonstrate that optimal Fe3O4 nanorods (NRs) can act agent with higher specific absorption rate (SAR), which mostly attributed to their enhanced surface anisotropy. As result, NRs could effectively hinder growth cancer cells in nude mice models, again demonstrating its good heating properties. These results provide...
Abstract Ovarian cancer is a common gynecological malignant tumor with high mortality rate and poor prognosis. There inadequate knowledge of the molecular mechanisms underlying ovarian cancer. We examined expression methyltransferase-like 3 (METTL3) in specimens using RT-qPCR, immunohistochemistry, Western blot analysis, tested methylation METTL3 by MSP. Levels METTL3, miR-1246, pri-miR-1246 CCNG2 were then analyzed their effects on cell biological processes also investigated, vivo assay to...
Abstract Endometrial cancer (EC) is a significant health threat to women, with recurrence after treatment posing major challenge. While abnormal cholesterol metabolism has been implicated in EC progression, the underlying mechanisms remain unclear. In this study, we identified lanosterol synthase (LSS) as key mediator associated EC. We found that LSS significantly upregulated tissues. Functional assays revealed promotes cell proliferation and migration, inhibits apoptosis, drives tumor...
The second messenger cyclic guanosine 3′,5′-monophosphate (cGMP) plays an important role in plant development and responses to stress. Recent studies indicated that cGMP is a secondary signal generated response auxin stimulation. also mediates auxin-induced adventitious root formation mung bean gravitropic bending soybean. Nonetheless, the mechanism of participation signalling affect these growth developmental processes largely unknown. In this report we provide evidence indole-3-acetic acid...
Objective To study the effect of type 2 diabetes mellitus(T2DM)on overall ovarian reserve and pregnancy outcomes during assisted reproductive technology (ART) among childbearing infertile women. Design Retrospective cohort study. Setting The Reproductive Medicine Special Hospital, First Hospital Lanzhou University, between January 2019 December 2022. Patient(s) A total 265 female patients aged 20–45 years who underwent in vitro fertilization-embryo transfer (IVF-ET), intracytoplasmic sperm...