A5080935494- Multiple Sclerosis Research Studies
- Peripheral Neuropathies and Disorders
- Alzheimer's disease research and treatments
- Glycosylation and Glycoproteins Research
- Dementia and Cognitive Impairment Research
- Systemic Sclerosis and Related Diseases
- Neuroscience and Neuropharmacology Research
- Monoclonal and Polyclonal Antibodies Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Epilepsy research and treatment
- Diet and metabolism studies
- Vascular Malformations Diagnosis and Treatment
- Health and Well-being Studies
- Tryptophan and brain disorders
- Metabolism and Genetic Disorders
- Medical Imaging Techniques and Applications
- Trace Elements in Health
- Neurological Disease Mechanisms and Treatments
- Mitochondrial Function and Pathology
- Health, Environment, Cognitive Aging
- Ophthalmology and Eye Disorders
- Hemoglobinopathies and Related Disorders
- Prion Diseases and Protein Misfolding
- Radiopharmaceutical Chemistry and Applications
- Neurological Disorders and Treatments
Aristotle University of Thessaloniki
2009-2023
AHEPA University Hospital
2011-2023
University of Thessaly
2019
Institute of Neuroimmunology of the Slovak Academy of Sciences
2013
Kimmerle's anomaly also known as ponticulus posticus is a common anatomical variation of the atlas, first cervical vertebra. It product complete or incomplete ossification posterior atlanto-occipital membrane over vertebral artery groove resulting in formation foramen (arcuate foramen) containing and branch C-1 spinal nerve. This has been associated with vertebro-basilar insufficiency symptoms, various types headaches, acute hearing loss. The aim present study to substantiate whether...
To investigate whether neurofilament light polypeptide (NfL) level in cerebrospinal fluid (CSF), currently a prognostic biomarker of neurodegeneration patients with multiple sclerosis (MS), may be potential cognitive dysfunction MS.This observational case-control study included MS. CSF levels NfL were determined using enzyme-linked immunosorbent assay. Cognitive function was measured the Brief International Assessment for MS (BICAMS) battery and Paced Auditory Serial Addition Test (PASAT3),...
Abstract Background Alzheimer’s disease (AD) is the most prevalent form of dementia. Currently, studied biomarkers AD are cerebrospinal fluid (CSF) amyloid β 1-42, total tau and phosphorylated tau. However, misdiagnosis can exceed 20%. Recently, we found that CSF precursor-like protein-1 (APLP1) neuronal pentraxin receptor (NPTXR) promising AD. The aim present study to validate APLP1 NPTXR as severity. Methods concentrations were measured in patients with mild cognitive impairment (MCI) (n =...
The authors measured levels of interleukin-6 (IL-6) and its soluble receptor in the serum a small series MS patients relapse, remission, control subjects, co-measuring depression. Results indicated that depression is not only very common during relapses MS, but also IL-6 increase acute phase disease, especially when detected.
Background: Increasing evidence suggests that gangliosides act as important mediators in both de- and remyelination. The scope of the present research was to investigate presence immunoglobulin (Ig) M antibodies against GM1, GD1b, GQ1b sera patients with dementia possible connection clinical parameters disease. Method: This topic demonstrates investigation 103 60 healthy individuals using enzyme-linked immunosorbent assay for 3 antiganglioside their sera. Results: authors report a positive...
The aim of this study was to evaluate the levels anti-GM1 in demented patients, correlating them with type and severity dementia as well eventually coexistent polyneuropathy. Anti-GM1 concentrations were measured sera 33 patients a male-to-female ratio 1:2.7 (the mean age 69.7 years for males 70.1 females). Eighty-two percent revealed increased values anti-GM1, but only 18.2% demonstrated polyneuropathies. Fifty-nine suffered from vascular dementia. most severely Mini-Mental State...
Aberrant motor behaviour or wandering refers to aimless movement without a specific purpose. Wandering is common in patients with dementia and leads early institutionalization caregivers' burden. Non-pharmacological interventions should be also considered as first-line solution for the because current pharmacological treatment has serious side-effects.A cross-over randomised controlled trial (RCT) 60 participants of all stages different types was conducted Greece. The sample randomly...
We examined the sera of 103 demented patients a mean age 75 years and 60 age-matched healthy individuals, using ELISA, to investigate levels IgM antibodies against GM1, GD1b, GQ1b gangliosides their possible correlation with clin
Little is known about whether tolerability and adherence to treatment can be influenced by weather temperature conditions. The objective of this study was assess monthly seasonal safety sc IFN-β1a (Rebif®, Merck) in relapsing-remitting multiple sclerosis (RRMS) patients using the RebiSmart® electronic autoinjector. A multicentre, prospective observational Greece adult RRMS with EDSS < 6, under Rebif®/RebiSmart® for ≤6 weeks before enrollment. primary endpoint monthly, annual over 12 months...
Abstract Background To the best of our knowledgedd, there is currently no case in literature reporting comorbidity Wilson’s and Creutzfeldt-Jakob disease (CJD), linked through copper. Case presentation A 44-year-old male with a history inherited (hepatolenticular degeneration), which manifested as mild liver injury psychiatric symptoms, was admitted to department due speech cognitive disturbances. Upon his admission, he had motor aphasia well psychomotor retardation an otherwise normal...
This article attempts to describe a very unusual case of boy aged 15, who has had intractable epileptic phenomena, mental retardation, megalocephaly, micrognathy, syndactyly, small tongue, hypoplastic genitalia, gynecomasty, obesity, and slight left body hemiatrophy. Neurologically the patient hypotonia lower limbs, cerebellar dysfunction including horizontal nystagmus, bilateral intention tremor, dysdiadokokinesia, gait ataxia. The clinical investigation revealed low plasma cholesterol...