A5032406936- Lymphoma Diagnosis and Treatment
- Acute Myeloid Leukemia Research
- Multiple Myeloma Research and Treatments
- Cancer Treatment and Pharmacology
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Hemoglobinopathies and Related Disorders
- Cancer, Stress, Anesthesia, and Immune Response
- Viral-associated cancers and disorders
- Glycosylation and Glycoproteins Research
- Monoclonal and Polyclonal Antibodies Research
- Venous Thromboembolism Diagnosis and Management
- Chronic Myeloid Leukemia Treatments
- Inflammatory Biomarkers in Disease Prognosis
- PI3K/AKT/mTOR signaling in cancer
- T-cell and Retrovirus Studies
- Ultrasound and Hyperthermia Applications
- Cancer survivorship and care
- Bone and Joint Diseases
- Epistemology, Ethics, and Metaphysics
- Cancer Diagnosis and Treatment
- Immunodeficiency and Autoimmune Disorders
- Inflammatory mediators and NSAID effects
- Inflammatory Myopathies and Dermatomyositis
- Augustinian Studies and Theology
GZA Ziekenhuizen Campus Sint-Augustinus
1997-2023
KU Leuven
1984
Plasma levels of D-dimer are elevated in cancer patients. Activation the extrinsic coagulation system and fibrinolytic cascade within a tumour is thought to be related with growth, invasion metastasis. We have investigated relationship between these markers fibrin metabolism, standard clinicopathological variables serum angiogenic cytokines three cohorts: group A (n=30) consisted 30 healthy female volunteers, B (n=23) consecutive patients operable breast C (n=84) untreated or progressive...
Patients with myelodysplastic syndromes suffer from an impaired quality of life that is only partially explained by physical symptoms. In observational study, we aimed to investigate the impact current MDS treatments and influence disease perception on life. Serial measurement health-related was performed 'the QUALMS', a validated MDS-specific patient reported outcome tool. Disease evaluated means Brief Illness Perception Questionnaire (B-IPQ). We prospectively collected data 75 patients...
Objective:To date, only a small number of epidemiological studies on myelofibrosis have been performed. The current study aimed to characterize the patient population in Belgium according pre-defined disease parameters (diagnosis, risk categories, hemoglobin <10 g/dl, spleen size, constitutional symptoms, platelet count, myeloblast count), with view obtaining deeper understanding proportion patients that may benefit from novel therapeutic strategies.Methods:A survey was used collect data...
Congenital prekallikrein deficiency is a rare disorder in which there an vitro clotting defect despite absence of bleeding or thrombotic tendency. In this report, 15-year-old boy with unexpected markedly prolonged activated partial thrombin time, normal prothrombin and without personal nor familial history thrombosis presented. Laboratory investigation revealed severe deficiency. This case highlights the importance following diagnostic algorithm to establish correct diagnosis. Moreover, by...
e19052 Background: Duvelisib (IPI-145), an oral dual inhibitor of PI3K-δ and -γ, is being evaluated as therapeutic for hematologic malignancies a monotherapy or in combination with anti-CD20 antibodies. Methods: CONTEMPO (NCT02391545) ongoing 2-part, 2-arm, Phase 1b/2 study evaluating the safety, pharmacokinetics, pharmacodynamics efficacy duvelisib combined antibodies rituximab (DR) obinutuzumab (DO) patients previously untreated CD20+ follicular lymphoma. administered at 25 mg BID...
Introduction: Mantle cell lymphoma is a B-cell non-Hodgkin’s characterized by t(11;14), resulting in overexpression of cyclin D1. Conventional chemotherapy obtains frequent (but short) remissions, leading to poor median overall survival (OS) 3–5 years. To obtain more information about the prevalence and current treatment (MCL) Belgium, we collected data Belgian registry MCL.Materials methods: All MCL patients, t(11;14) and/or D1 positive, seen hematology departments over one-year period...
Case presentation We report three cases of vitamin B12 and/or folic acid deficiencies presenting with non-immune hemolytic anemia and thrombocytopenia. This presentation, features a thrombotic microangiopathy (TMA), has earlier been described as 'pseudo-TMA'.