A5067485627- Methane Hydrates and Related Phenomena
- Seismic Waves and Analysis
- Earthquake Detection and Analysis
- Seismology and Earthquake Studies
- Photosynthetic Processes and Mechanisms
- Spectroscopy and Quantum Chemical Studies
- Analytical chemistry methods development
- Gut microbiota and health
- Electrocatalysts for Energy Conversion
- Electrochemical sensors and biosensors
- Electrochemical Analysis and Applications
- Nanomaterials for catalytic reactions
- Ginger and Zingiberaceae research
- Adsorption and biosorption for pollutant removal
- Pharmaceutical and Antibiotic Environmental Impacts
- Advanced Glycation End Products research
- Environmental remediation with nanomaterials
- Magnetic and transport properties of perovskites and related materials
- Advanced NMR Techniques and Applications
- Fuel Cells and Related Materials
- Ammonia Synthesis and Nitrogen Reduction
- Microbial Fuel Cells and Bioremediation
- Receptor Mechanisms and Signaling
- Photochemistry and Electron Transfer Studies
- Advanced Thermoelectric Materials and Devices
Jiangsu University
2020-2025
State Key Laboratory of Pollution Control and Resource Reuse
2022-2025
Tongji University
2022-2025
Shanghai Institute of Pollution Control and Ecological Security
2022-2025
Shanghai Electric (China)
2024
Changsha University of Science and Technology
2021-2024
Peking University
2024
Peking University People's Hospital
2024
Vollum Institute
2023
Oregon Health & Science University
2018-2023
Abstract Background 5-Fluorouracil (5-FU) is a used chemotherapy drug for cancer, and its main side effect intestinal mucositis which causes to fail. It was known that short-chain fatty acids (SCFAs) can inhibit immune cell release of various proinflammatory factors excessive inflammation. However, the inhibitory SCFAs on 5-FU-induced still unclear. Results To simulate effects epithelial cells, cells (THP-1 Caco-2 cells) were pretreated with sodium acetate (NaAc), propionate (NaPc) butyrate...
Abstract Type A γ-aminobutyric acid receptors (GABA Rs) are the principal inhibitory in brain and target of a wide range clinical agents, including anaesthetics, sedatives, hypnotics antidepressants 1–3 . However, our understanding GABA R pharmacology has been hindered by vast number pentameric assemblies that can be derived from 19 different subunits 4 lack structural knowledge clinically relevant receptors. Here, we isolate native murine containing widely expressed α1 subunit elucidate...
The application of anion exchange membrane fuel cells is hampered by the development highly efficient and earth-abundant anode hydrogen oxidation reaction (HOR) catalysts. Here, a series nickel catalysts (denoted as Ni-X) with different lattice oxygen (LO) contents were synthesized H2 reduction hydroxide at temperatures (X) ranging from 300 to 500 °C. Ni-400 (LO/Ni = 0.41, NiO0.41) catalyst an optimum LO content showed excellent HOR activity stability, comparable current Ni-based...
Recyclable magnetic COFs/Fe 3 O 4 synthesized using ball-milling showed fast and high adsorption for two PFOS PFOA substitutes in water.
Egg production levels in late laying hens are negatively correlated with increasing age. Decreased liver and ovarian function aging is accompanied by decreased antioxidant capacity, reproductive hormone levels, follicular development, resulting synthesis of yolk precursors. The golden needle mushroom (Flammulina velutipes) has been reported to exhibit anti-inflammatory, antioxidant, hypolipidemic properties. We aimed reveal the therapeutic effects F. velutipes stem (FVS) on liver-blood-ovary...
Currently, stem cells are a prominent focus of regenerative engineering research. However, due to the limitations commonly used cell sources, their application in therapy is often restricted experimental stage and constrained by ethical considerations. In contrast, urine-derived (USCs) offer promising advantages for clinical trials applications. The noninvasive nature collection process allows repeated retrieval within short period, making it more feasible option. Moreover, studies have...
Hydrogen peroxide (H2O2) is an environment-friendly oxidant with wide applications in daily life and chemical industry. The electrochemical production of H2O2 through the two-electron oxygen reduction (2e− ORR) process has...
Inflammatory bowel disease (IBD) has become a global healthcare issue, with its incidence continuing to rise, but currently there is no complete cure. Xylitol widely used sweetener in various foods and beverages, limited research on the effects of xylitol IBD symptoms. Study effect oral improving intestinal inflammation damage mice, further explore mechanism alleviating symptoms using microbiota non-targeted metabolomics techniques. An mouse model was induced sodium dextran sulfate (DSS)....
Short-chain fatty acids (SCFAs) are important anti-inflammatory metabolites of intestinal flora. Oxidized low-density lipoprotein (ox-LDL)-induced macrophage activation is critical for the formation atherosclerosis plaque. However, association between SCFAs and ox-LDL-induced with respect to plaque has not yet been elucidated. The present study investigated whether (sodium acetate, sodium propionate, butyrate) can affect potential signaling pathways via regulation expression NLRP3/Caspase-1...
Nonalcoholic fatty liver disease (NAFLD) is the most prevalent chronic in modern society. It characterized by an accumulation of lipids and excessive inflammatory response. Clinical trials have provided evidence that probiotics may prevent onset relapse NAFLD. The aim this study was to explore effect Lactiplantibacillus plantarum NKK20 strain (NKK20) on high-fat-diet-induced NAFLD ICR murine model propose underlying mechanism whereby protects against results showed administration ameliorated...
In recent years, sodium butyrate has gained increased attention for its numerous beneficial properties. However, whether could alleviate inflammatory damage by macrophage activation and underlying mechanism remains unclear. The present study used an advanced glycosylation products- (AGEs-) induced model to oxidative stress, inflammation, metabolic dysfunction of human monocyte-macrophage originated THP-1 cells in a PI3K-dependent autophagy pathway. results indicated that alleviated the...
This study aims to evaluate the effect of berberine-based carbon quantum dots (Ber-CDs) on improving 5-fluorouracil (5-FU)-induced intestinal mucositis in C57BL/6 mice, and explored mechanisms behind this effect. Thirty-two mice were divided into four groups: normal control (NC), 5-FU-induced model (5-FU), 5-FU + Ber-CDs intervention (Ber-CDs), native berberine (Con-CDs). The improved body weight loss with compared group. expressions IL-1β NLRP3 spleen serum Con-Ber groups significantly...
Nephropathy injury is a prevalent complication observed in individuals with diabetes, serving as prominent contributor to end-stage renal disease, and the advanced glycation products (AGEs) are important factors that induce kidney patients diabetes. Addressing this condition remains challenging aspect clinical practice. The aim of study was explore effects Lactiplantibacillus plantarum NKK20 strain (NKK20) which protects against diabetic disease (DKD) based on animal cell models. results...