- Colorectal Cancer Surgical Treatments
- Diverticular Disease and Complications
- Enhanced Recovery After Surgery
- Nutrition and Health in Aging
- Anorectal Disease Treatments and Outcomes
- Pelvic floor disorders treatments
- Abdominal Surgery and Complications
- Frailty in Older Adults
- Hernia repair and management
- Cardiac, Anesthesia and Surgical Outcomes
- Tryptophan and brain disorders
- Osteoarthritis Treatment and Mechanisms
- Diagnosis and treatment of tuberculosis
- Venous Thromboembolism Diagnosis and Management
- Colorectal and Anal Carcinomas
- Facial Nerve Paralysis Treatment and Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Stoma care and complications
- Pancreatic and Hepatic Oncology Research
- Maternal and Perinatal Health Interventions
- Stress Responses and Cortisol
- Head and Neck Anomalies
- Multiple and Secondary Primary Cancers
- PARP inhibition in cancer therapy
- Multiple Myeloma Research and Treatments
Cleveland Clinic
2023-2024
Royal Prince Alfred Hospital
2022-2023
The University of Notre Dame Australia
2023
Icahn School of Medicine at Mount Sinai
2022-2023
Peter MacCallum Cancer Centre
2004-2023
Sydney Local Health District
2022
St Vincent's Hospital Sydney
2019-2021
Chinese University of Hong Kong
2010-2019
Abstract Chronic stress induces changes in the periphery and central nervous system (CNS) that contribute to neuropathology behavioral abnormalities associated with psychiatric disorders. In this study, we examined impact of peripheral inflammation during chronic social defeat (CSDS) female mice. Compared male mice, found mice exhibited heightened inflammatory response identified C-C motif chemokine ligand 5 (CCL5), as a stress-susceptibility marker females. Blocking CCL5 signaling promoted...
Anal cancer is an uncommon condition, occurring at higher rates in specific subpopulations. Clinical experience limited and substantial changes have recently occurred our understanding of this condition. We, therefore, set out to characterize patients presenting with anal investigate whether there been any over the past 20 years.Retrospective audit cases identified from pathology clinical databases during period 1 January 2000 31 December 2019.Two hundred sixteen had squamous cell...
Abstract Background Prospective studies demonstrate that over one‐third of patients undergoing standard suture closure laparotomy wounds will develop incisional hernias (IHs). Whilst prophylactic mesh has been demonstrated to decrease IH rates in clean wounds, associated with high seroma formation (>30%), infection (>10%) and pain, discouraging many surgeons from using mesh, especially combined intestinal surgery. The aim this study is review the experience a single colorectal surgeon...
Endoscopic retrograde cholangio-pancreatography (ERCP) has higher rates of morbidity and mortality compared to upper or lower gastrointestinal tract endoscopy. The availability magnetic resonance cholangiopancreatography means ERCP is usually performed for therapeutic purposes. Simulation could provide an adjunct patient-based training in however models date have been unconvincing.This simulation model was constructed from moulded meshed silicone by co-designers: Jean Wong Kai Cheng....
Abstract Aim The role of germline testing in prostate cancer is evolving and knowledge an individual's genetic profile may be used to guide not only assessment their familial risk but also have prognostic therapeutic implications. Although international guidelines incorporated recommendations for cancer, there little Australian data referrals. aim this study review the frequency relevant pathogenic mutations center, associated clinical factors impact. Methods We conducted a single‐center...
We demonstrate the technical details of laparoscopic-assisted endoscopic 'clean sweep' for small bowel polyp clearance in Peutz Jeghers Syndrome. A reduces risk future recurrences but was previously performed with an open technique. minimally invasive approach is safe, trauma and has good postoperative outcomes.
Endoscopic submucosal dissection (ESD) is an advanced therapeutic technique used to remove non-malignant polyps (NMP) and early cancers. Benefits include reducing unnecessary colectomies, cost, morbidity of NMP treatment. Other roles for ESD associated skills are likely expand in the future, including non-operative management rectal cancer. The learning curve feasible with established training methods. Colorectal surgeons already perform routine endoscopy manage endoscopic complications...
At present in Australia women are not routinely, systematically informed of the risks childbirth.It is hoped this presentation perspective some who suffer unexpected obstetric complications will encourage change.The experience involved medicolegal reports prepared by a colorectal surgeon over ten years analysed.Twenty were identified. Sixteen had vaginal deliveries. All 16 suffered third or fourth-degree tears, six developed rectovaginal fistulae, required stomas and 11 faecal incontinence....
Abstract Background Frailty is associated with a prodromal stage called pre-frailty, potentially reversible and highly prevalent condition before frailty becomes established. Despite this, there no widely accepted definition of pre-frailty to support its early identification management. This study applied an international consensus approach define better understand pre-frailty. Methods A modified electronic two-round Delphi Consensus was conducted. In all, 23 experts from 12 countries...
Despite national and international efforts for the prevention of metabolic syndrome its underlying diseases/disorders, prevalence is still rising, especially in middle-aged population. In this study, we explore effect high fat diet on development mice to evaluate potential benefits voluntary physical exercise periphery as well brain cognitive function, mechanisms. We found that developed at middle age significantly impairs function impairment associated with gene dysregulation pathways are...
Tai-chi (TCC) is a low to moderate intensity aerobic exercise which emphasizes on mental calmness and slow-control breathing while practising, unlike other forms of do not have such recommendations. It known if combination physical strategy would bring along better health-related qulaity life than alone. Limited studies are found evaluate the impact TCC self-reported health health. PURPOSE: The purpose present study was compare effect quality between Walking (WLK) from 12-week intervention,...
You have accessJournal of UrologyPediatrics: Stone Disease1 Apr 20101048 WITHDRAWN: PEDIATRIC UROLITHIASIS: MEDICAL TREATMENT AND OUTCOMES Jean Wong, Israel Franco, Steven Friedman, Murali Pagala, and Robert Weiss WongJean Wong Brooklyn, NY More articles by this author , FrancoIsrael Franco Valhalla, FriedmanSteven Friedman PagalaMurali Pagala WeissRobert View All Author Informationhttps://doi.org/10.1016/j.juro.2010.02.2160AboutPDF ToolsAdd to favoritesDownload CitationsTrack...
2568 Background: Dendritic cell (DC) immunotherapy is being actively studied in patients (pts) with multiple myeloma (MM). However, the best route of injection these cells unknown. The aim this study was to determine vivo distribution DC when given pts MM via varying routes by using nuclear medicine imaging techniques. Methods: Eligible had stable or slowly progressive not requiring systemic treatment, elevated serum MUC-1 positive marrow plasma staining. were produced vitro culture...
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