A5089640204- Photodynamic Therapy Research Studies
- Phenothiazines and Benzothiazines Synthesis and Activities
- Porphyrin and Phthalocyanine Chemistry
- Nanoplatforms for cancer theranostics
- Pickering emulsions and particle stabilization
- Proteins in Food Systems
- Innovative Microfluidic and Catalytic Techniques Innovation
- Photochemistry and Electron Transfer Studies
- Gold and Silver Nanoparticles Synthesis and Applications
- Microfluidic and Capillary Electrophoresis Applications
- Organic Chemistry Cycloaddition Reactions
- bioluminescence and chemiluminescence research
- Photonic and Optical Devices
- Quinazolinone synthesis and applications
- Natural Antidiabetic Agents Studies
- Advanced X-ray Imaging Techniques
- Digital Holography and Microscopy
- Electrohydrodynamics and Fluid Dynamics
- Antibiotics Pharmacokinetics and Efficacy
- Synthesis and Biological Evaluation
- Edible Oils Quality and Analysis
- Chemical Reactions and Mechanisms
- Biochemical Analysis and Sensing Techniques
- Cancer Treatment and Pharmacology
- Bioactive Compounds and Antitumor Agents
National Institute for Laser Plasma and Radiation Physics
2014-2024
University of Bucharest
2013-2015
This paper presents a spectroscopic study of emulsions generated with laser-assisted device. Fourier transform infrared (FTIR), Raman and UV–Vis–NIR reflectance spectra emulsions, recorded before after exposure to laser radiation were used characterize the effect irradiation. The also comparison between calculated IR experimental FTIR an emulsion’s components. measurements allowed identification absorption bands specific each emulsions’ Moreover, it enabled observation destabilization...
Multidrug resistance of bacteria is a worrying concern in the therapeutic field and an alternative method to combat it designing new efflux pump inhibitors (EPIs). This article presents molecular study two quinazoline derivatives, labelled BG1189 BG1190, proposed as EPIs. In silico approach investigates pharmacodynamic pharmacokinetic profile BG1190 quinazolines. Molecular docking predicted ADMET features suggest that may represent attractive candidates antimicrobial drugs. UV-Vis absorption...
This study presents the spectral characterization of TiO2 nanoparticles (NPs) functionalized with three porphyrin derivatives: 5,10,15,20-(Tetra-4-aminophenyl) (TAPP), 5,10,15,20-(Tetra-4-methoxyphenyl) (TMPP), and 5,10,15,20-(Tetra-4-carboxyphenyl) (TCPP). UV-Vis absorption Fourier transform infrared spectroscopy-attenuated total reflection (FTIR-ATR) spectroscopic studies these porphyrins their complexes NPs were performed. In addition, efficiency singlet oxygen generation, key species in...
The combination of TiO2 nanoparticles (NPs) and photosensitizers (PS) may offer significant advantages in photodynamic therapy (PDT) melanoma, such as improved cell penetration, enhanced ROS production, cancer selectivity. In this study, we aimed to investigate the effect 5,10,15,20-(Tetra-N-methyl-4-pyridyl)porphyrin tetratosylate (TMPyP4) complexes with NPs on human cutaneous melanoma cells by irradiation 1 mW/cm2 blue light. porphyrin conjugation was analyzed absorption FTIR spectroscopy....
The study reports an investigation of the photoproducts obtained by exposure chlorpromazine hydrochloride in ultrapure water (concentration 2 mg/mL) to a 266-nm laser beam fourth harmonic generation from Nd:YAG (6-ns full time width at half maximum, 10-Hz pulse repetition rate). were analyzed steady-state UV-Vis absorption, laser-induced fluorescence, Fourier transform infrared spectroscopy, and liquid chromatography–tandem time-of-flight mass spectroscopy. Two figures showing pathways that...
Photodynamic therapy has the potential to be a new and effective cancer treatment. Even if in vitro vivo research show promise, molecular mechanism remains unclear. In this study, docking simulations predict binding affinity of 5,10,15,20-tetrakis(4'-sulfonatophenyl)-porphyrin tetraammonium photosensitizer on several targets photodynamic Our results indicate that binds receptor targets, including B-cell lymphoma 2 (BCL-2) other related proteins BCL-xL, MCL-1, or A1. The porphyrin derivative...
This paper reports results obtained using white light diffraction phase microscopy (wDPM) on captured images of breast and colon tissue samples, marking a contribution to the advancement in biomedical imaging. Unlike conventional brightfield microscopy, wDPM offers capability capture intricate details biological specimens with enhanced clarity precision. It combines high resolution, contrast, quantitative capabilities non-invasive, label-free These features make it useful tool for imaging,...
Anna A. Oleshkevich, Specific features of change in enzymate activity