A5081352398- Photodynamic Therapy Research Studies
- Spectroscopy and Laser Applications
- Porphyrin and Phthalocyanine Chemistry
- Photochemistry and Electron Transfer Studies
- Phenothiazines and Benzothiazines Synthesis and Activities
- Laser-induced spectroscopy and plasma
- Nanoplatforms for cancer theranostics
- Advanced Chemical Physics Studies
- Laser-Ablation Synthesis of Nanoparticles
- bioluminescence and chemiluminescence research
- Atmospheric Ozone and Climate
- Laser Design and Applications
- Analytical chemistry methods development
- Quantum, superfluid, helium dynamics
- Photonic and Optical Devices
- Semiconductor Lasers and Optical Devices
- Molecular Spectroscopy and Structure
- Atmospheric chemistry and aerosols
- Surface Modification and Superhydrophobicity
- Laser-Matter Interactions and Applications
- Photopolymerization techniques and applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Environmental Toxicology and Ecotoxicology
- Analytical Chemistry and Sensors
- Electrowetting and Microfluidic Technologies
National Institute for Laser Plasma and Radiation Physics
2015-2024
University of Bucharest
2007-2016
Military Hospital
2009
Ophthalmology Clinic
2009
Central Military Hospital
2009
Clinical Emergency Hospital Bucharest
2009
Mediterranean University
2009
Friedrich Schiller University Jena
2004-2009
Helmholtz Institute Jena
2005-2008
Max Planck Institute for Astronomy
2005-2008
This paper presents a spectroscopic study of emulsions generated with laser-assisted device. Fourier transform infrared (FTIR), Raman and UV–Vis–NIR reflectance spectra emulsions, recorded before after exposure to laser radiation were used characterize the effect irradiation. The also comparison between calculated IR experimental FTIR an emulsion’s components. measurements allowed identification absorption bands specific each emulsions’ Moreover, it enabled observation destabilization...
Carbon soot has been prepared by laser-induced pyrolysis of a mixture ethylene (C2H4) and benzene (C6H6) vapor. The soluble part the carbonaceous powder separated from its insoluble counterpart soxhlet extraction in toluene. Several techniques were applied to obtain information on composition extract. These included UV/visible IR spectroscopy solid liquid phase, gas chromatography combined with mass spectrometry, gas-phase laser supersonic jet, matrix helium droplets, latter being also...
Introduction Phenothiazines when exposed to white light or UV radiation undergo a variety of reactions that result in degradation parental compound and formation new species. This process is slow may be sped up with exposure high energy such as produced by laser. Methods Varying concentrations Chlorpromazine Hydrochloride (CPZ) (2–20 mg/mL distilled water) were 266 nm laser beam (time intervals: 1–24 hrs). At distinct intervals the irradiation products evaluated spectrophotometry between...
This study presents the spectral characterization of TiO2 nanoparticles (NPs) functionalized with three porphyrin derivatives: 5,10,15,20-(Tetra-4-aminophenyl) (TAPP), 5,10,15,20-(Tetra-4-methoxyphenyl) (TMPP), and 5,10,15,20-(Tetra-4-carboxyphenyl) (TCPP). UV-Vis absorption Fourier transform infrared spectroscopy-attenuated total reflection (FTIR-ATR) spectroscopic studies these porphyrins their complexes NPs were performed. In addition, efficiency singlet oxygen generation, key species in...
The combination of TiO2 nanoparticles (NPs) and photosensitizers (PS) may offer significant advantages in photodynamic therapy (PDT) melanoma, such as improved cell penetration, enhanced ROS production, cancer selectivity. In this study, we aimed to investigate the effect 5,10,15,20-(Tetra-N-methyl-4-pyridyl)porphyrin tetratosylate (TMPyP4) complexes with NPs on human cutaneous melanoma cells by irradiation 1 mW/cm2 blue light. porphyrin conjugation was analyzed absorption FTIR spectroscopy....
The study reports an investigation of the photoproducts obtained by exposure chlorpromazine hydrochloride in ultrapure water (concentration 2 mg/mL) to a 266-nm laser beam fourth harmonic generation from Nd:YAG (6-ns full time width at half maximum, 10-Hz pulse repetition rate). were analyzed steady-state UV-Vis absorption, laser-induced fluorescence, Fourier transform infrared spectroscopy, and liquid chromatography–tandem time-of-flight mass spectroscopy. Two figures showing pathways that...
Even today, breast cancer remains a global public problem, with high mortality rate among women. Nanoparticle (NP) based systems are developed to enhance drug delivery, reducing the toxic effect of medicine molecules. By using iron oxide nanoparticles for treatment, several advantages were highlighted: ability target specific locations derived from their magnetic properties and reduced side effects. The aim this study was examine on cell line anticancer potential γ-Fe2O3 NPs loaded...
In a series of experiments devoted to the study polycyclic aromatic hydrocarbons for astrophysical applications, S2←S0 transition jet-cooled pyrene (C16H10) at 321 nm has been studied by an absorption technique first time. The spectra observed cavity ring-down spectroscopy closely resemble excitation obtained earlier laser-induced fluorescence (LIF) and show same band clusters arising from vibronic interaction S2 with S1. We have also investigated when it was incorporated into 380 mK cold...
Ciprofloxacin is one of the most prescribed antibiotics in treating bacterial infections, becoming an important pollutant wastewaters. Moreover, ciprofloxacin hard to be destroyed by conventional water treatment processes; therefore, efficient treatments destroy it are needed decontamination. This study offers insights into performance 266 nm laser beams on photodegradation ciprofloxacin. An Nd:YAG was used that emitted at energy 6.5 mJ (power 65 mW) and solutions were irradiated up 240 min....
Whereas exposure of combinations a phenothiazine and bacterium to incoherent UV increases the activity phenothiazine, alone does not yield an increase its activity. Because laser beam energy is greater than that produced by sources, phenothiazines specific lasers may molecules with altered activities over unexposed parent. Chlorpromazine, thioridazine promethazine active against bacteria were exposed two distinct for varying periods time. Absorption fluorescence spectra conducted prior...
In this paper, laser beam resonant interaction with pendant microdroplets that are seeded a dye (Rhodamine 6G (Rh6G)) water solution or oily Vitamin A emulsion Rhodamine in is investigated through fluorescence spectra analysis. The excitation made the second harmonic generated emitted by pulsed Nd:YAG system at 532 nm. containing exhibit an enhanced signal. This effect can be explained as being due to scattering of light sub-micrometric drops and spherical geometry droplet. droplet acts...
The study of the S1(1A1)<--S0(1A1) transition benzo[g,h,i]perylene (BghiP, C22H12) in supersonic jets and solid rare gas matrices is reported. In jet-cooled spectrum, origin band position located at 25,027.1+/-0.2 cm-1, assignment being supported by analysis vibrational shifts rotational contours. Except for band, which weak, all bands are attributed to fundamental excitation nontotally symmetric b1 modes S1. intensity pattern interpreted as a consequence weak oscillator strength electronic...
The purpose of this study was to investigate the effectiveness in photodynamic therapy iron oxide nanoparticles (γ-Fe
Photodynamic therapy has the potential to be a new and effective cancer treatment. Even if in vitro vivo research show promise, molecular mechanism remains unclear. In this study, docking simulations predict binding affinity of 5,10,15,20-tetrakis(4'-sulfonatophenyl)-porphyrin tetraammonium photosensitizer on several targets photodynamic Our results indicate that binds receptor targets, including B-cell lymphoma 2 (BCL-2) other related proteins BCL-xL, MCL-1, or A1. The porphyrin derivative...
Compounds from plants that are used in traditional medicine may have medicinal properties. It is well known belonging to the genus Aconitum highly poisonous. Utilizing substances derived
Hydrogels are ideal candidates for the sustained local administration of antimicrobial drugs because they have customizable physicochemical properties that allow drug release kinetics to be controlled and potentially address issue systemic side effects. Consequently, purpose this study was use 266 nm-pulsed laser beams photo-crosslink gelatin methacryloyl hydrogels using Irgacure 2959 as a photo-initiator reduce curing time an online method monitor process, such laser-induced fluorescence....