A5036135183- Phenothiazines and Benzothiazines Synthesis and Activities
- Photodynamic Therapy Research Studies
- Photochemistry and Electron Transfer Studies
- Porphyrin and Phthalocyanine Chemistry
- Innovative Microfluidic and Catalytic Techniques Innovation
- Bioactive Compounds and Antitumor Agents
- bioluminescence and chemiluminescence research
- Essential Oils and Antimicrobial Activity
- Photonic and Optical Devices
- Nanoplatforms for cancer theranostics
- Surface Modification and Superhydrophobicity
- Laser-Matter Interactions and Applications
- Electrowetting and Microfluidic Technologies
- Photopolymerization techniques and applications
- Random lasers and scattering media
- Nanomaterials and Printing Technologies
- Antibiotics Pharmacokinetics and Efficacy
- Chemical Reactions and Mechanisms
- Semiconductor Lasers and Optical Devices
- Analytical Chemistry and Sensors
- Laser Applications in Dentistry and Medicine
- Chemical synthesis and alkaloids
- Advanced Fluorescence Microscopy Techniques
- Additive Manufacturing and 3D Printing Technologies
- Biosensors and Analytical Detection
National Institute for Laser Plasma and Radiation Physics
2014-2024
University of Bucharest
2013-2017
Introduction Phenothiazines when exposed to white light or UV radiation undergo a variety of reactions that result in degradation parental compound and formation new species. This process is slow may be sped up with exposure high energy such as produced by laser. Methods Varying concentrations Chlorpromazine Hydrochloride (CPZ) (2–20 mg/mL distilled water) were 266 nm laser beam (time intervals: 1–24 hrs). At distinct intervals the irradiation products evaluated spectrophotometry between...
This study presents the spectral characterization of TiO2 nanoparticles (NPs) functionalized with three porphyrin derivatives: 5,10,15,20-(Tetra-4-aminophenyl) (TAPP), 5,10,15,20-(Tetra-4-methoxyphenyl) (TMPP), and 5,10,15,20-(Tetra-4-carboxyphenyl) (TCPP). UV-Vis absorption Fourier transform infrared spectroscopy-attenuated total reflection (FTIR-ATR) spectroscopic studies these porphyrins their complexes NPs were performed. In addition, efficiency singlet oxygen generation, key species in...
The combination of TiO2 nanoparticles (NPs) and photosensitizers (PS) may offer significant advantages in photodynamic therapy (PDT) melanoma, such as improved cell penetration, enhanced ROS production, cancer selectivity. In this study, we aimed to investigate the effect 5,10,15,20-(Tetra-N-methyl-4-pyridyl)porphyrin tetratosylate (TMPyP4) complexes with NPs on human cutaneous melanoma cells by irradiation 1 mW/cm2 blue light. porphyrin conjugation was analyzed absorption FTIR spectroscopy....
The study reports an investigation of the photoproducts obtained by exposure chlorpromazine hydrochloride in ultrapure water (concentration 2 mg/mL) to a 266-nm laser beam fourth harmonic generation from Nd:YAG (6-ns full time width at half maximum, 10-Hz pulse repetition rate). were analyzed steady-state UV-Vis absorption, laser-induced fluorescence, Fourier transform infrared spectroscopy, and liquid chromatography–tandem time-of-flight mass spectroscopy. Two figures showing pathways that...
Ciprofloxacin is one of the most prescribed antibiotics in treating bacterial infections, becoming an important pollutant wastewaters. Moreover, ciprofloxacin hard to be destroyed by conventional water treatment processes; therefore, efficient treatments destroy it are needed decontamination. This study offers insights into performance 266 nm laser beams on photodegradation ciprofloxacin. An Nd:YAG was used that emitted at energy 6.5 mJ (power 65 mW) and solutions were irradiated up 240 min....
Whereas exposure of combinations a phenothiazine and bacterium to incoherent UV increases the activity phenothiazine, alone does not yield an increase its activity. Because laser beam energy is greater than that produced by sources, phenothiazines specific lasers may molecules with altered activities over unexposed parent. Chlorpromazine, thioridazine promethazine active against bacteria were exposed two distinct for varying periods time. Absorption fluorescence spectra conducted prior...
In this paper, laser beam resonant interaction with pendant microdroplets that are seeded a dye (Rhodamine 6G (Rh6G)) water solution or oily Vitamin A emulsion Rhodamine in is investigated through fluorescence spectra analysis. The excitation made the second harmonic generated emitted by pulsed Nd:YAG system at 532 nm. containing exhibit an enhanced signal. This effect can be explained as being due to scattering of light sub-micrometric drops and spherical geometry droplet. droplet acts...
The purpose of this study was to investigate the effectiveness in photodynamic therapy iron oxide nanoparticles (γ-Fe
Varying concentrations of Chlorpromazine Hydrochloride (CPZ) were exposed to a 266 nm laser beam for varying periods time ranging from 4 24 hrs and the products irradiation evaluated activity against panel bacteria that consisted representatives Gram-positives Gram-negatives expressed different degrees efflux pump activity, compared parental unexposed compound with prolonged irradiation.Whereas antibacterial product Staphylococcus aureus Escherichia coli strains was many folds greater, no...
Hydrogels are ideal candidates for the sustained local administration of antimicrobial drugs because they have customizable physicochemical properties that allow drug release kinetics to be controlled and potentially address issue systemic side effects. Consequently, purpose this study was use 266 nm-pulsed laser beams photo-crosslink gelatin methacryloyl hydrogels using Irgacure 2959 as a photo-initiator reduce curing time an online method monitor process, such laser-induced fluorescence....
Results for the interaction of a 532 nm pulsed laser beam with individual pendant rhodamine 6G dye droplets large-size parameter, x≈7300, are reported. By varying concentration and pumping energy, typical fluorescence bands detected in such cases obtained, along narrow, instantly, or gradually blueshifted band assigned to lasing effect at droplet surface. The maximum blueshift value peak wavelength is associated gain curve when self-absorption effects not present. Lasing position further...
Fluorescence and lasing emission that are produced separately in time during excitation laser pulse for an mm-sized Rhodamine 6G dye-water droplet reported. The acts as a quasi-spherical closed optical resonator due to multiple internal reflections, the resonant amplified is delayed with respect fluorescence emission. Measurements of temporal evolution droplet's were performed by varying signal acquisition gate width delay pumping pulse. spectra structured two bands which appear one after...
Introduction: Phenothiazines when exposed to white light or UV radiation undergo a variety of reactions that result in degradation parental compound and formation new species.This process is slow may be sped up with exposure high energy such as produced by laser. Methods:Varying concentrations Chlorpromazine Hydrochloride (CPZ) (2-20 mg/mL distilled water) were 266 nm laser beam (time intervals: 1-24 hrs).At distinct intervals the irradiation products evaluated spectrophotometry between...