Yixun Chen

ORCID: 0000-0001-6145-9091
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About
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Research Areas
  • Ferroptosis and cancer prognosis
  • Nerve injury and regeneration
  • Hereditary Neurological Disorders
  • Advanced Thermoelectric Materials and Devices
  • Neurological Disease Mechanisms and Treatments
  • Flavonoids in Medical Research
  • Bone Metabolism and Diseases
  • RNA modifications and cancer
  • Health, Environment, Cognitive Aging
  • Advanced Sensor and Energy Harvesting Materials
  • Dementia and Cognitive Impairment Research
  • Innovative Energy Harvesting Technologies
  • Bone health and osteoporosis research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Bone fractures and treatments
  • Lung Cancer Research Studies
  • Image Enhancement Techniques
  • Parental Involvement in Education
  • Health disparities and outcomes
  • Youth Development and Social Support
  • interferon and immune responses
  • Wnt/β-catenin signaling in development and cancer
  • Child and Adolescent Psychosocial and Emotional Development
  • Tea Polyphenols and Effects
  • Prostate Cancer Treatment and Research

Nantong University
2022-2024

Affiliated Hospital of Nantong University
2022-2024

Guangdong University of Finance
2023

Sichuan University
2022

Guangxi University of Science and Technology
2021

Peking University People's Hospital
2015-2016

Peking University
2015-2016

Abstract Fiber- and yarn-based thermoelectric materials play an essential role in the design of fabric-based flexible generators (FTEGs) which may overcome wearable difficulties existing film-based FTEGs. In this study, we used a robust coating method to produce high-performance yarns for applications. An organic/inorganic hybrid agent composed PEDOT:PSS, MWCNT, Bi 2 Te 3 was coat alkali modified porous polyester yarn. The material contributes improved properties. modification improves...

10.1088/1361-665x/acba64 article EN Smart Materials and Structures 2023-02-08

Abstract Aims The aim of this study was to evaluate the effect epicatechin, on neurological recovery and neuroinflammation after traumatic brain injury (TBI) investigate its potential value in clinical practice. Methods TBI model established adult rats by CCI method. epicatechin evaluated intraperitoneal injection. Neurological assessed Morris Water Maze, mNSS score, Rotarod test Adhesive removal test. Protein gene expression Western blot, ELISA, PCR immunofluorescence. Furthermore, use AKT...

10.1111/cns.14364 article EN cc-by CNS Neuroscience & Therapeutics 2023-07-18

Brain metastasis (BMs) in small cell lung cancer (SCLC) has a very poor prognosis. This study combined WGCNA with the mfuzz algorithm to identify potential biomarkers peripheral blood of patients BMs. By comparing significantly differentially expressed genes present BMs samples, we identified ADCY4 as target for further study. Expression was used cluster expression pattern, and 28 hub functional enrichment. PPI network analysis were obtained by GABRE, NFE4 LMOD2 are highly have good...

10.1016/j.heliyon.2024.e28162 article EN cc-by-nc Heliyon 2024-03-28

Abstract Background Lung adenocarcinoma (LUAD) is one of the most invasive malignant tumor respiratory system. It also common pathological type leading to death LUAD. Maintaining homeostasis immune cells an important way for anti‐tumor immunotherapy. However, biological significance maintaining and therapeutic effect has not been well studied. Methods We constructed a diagnostic prognostic model LUAD based on B T homeostasis‐related genes. Minimum absolute contraction selection operator...

10.1111/crj.13755 article EN cc-by The Clinical Respiratory Journal 2024-05-01

Abstract The incidence of intracerebral hemorrhage (ICH) is increasing every year, with very high rates mortality and disability. prognosis elderly ICH patients extremely unfavorable. Interleukin, as an important participant in building the inflammatory microenvironment central nervous system after ICH, has long been focus neuroimmunology research. However, there are no studies on role IL31 play pathologic process ICH. We collected para‐lesion tissue for immunofluorescence flow cytometry...

10.1111/bpa.13245 article EN cc-by Brain Pathology 2024-02-14

Prostate stem cell antigen (PSCA) is associated with disease progression, promotion of angiogenesis, invasion, metastasis and immune evasion in cancer. However, its expression pattern diagnostic prognostic potential have not been thoroughly analysed from a pan-cancer perspective. This study aimed to examine the effects PSCA on prognosis inflammatory infiltration patterns various cancer types. We relationship between immunological subtypes tumor microenvironment (TME) role molecular subtypes,...

10.1371/journal.pone.0298469 article EN cc-by PLoS ONE 2024-06-25

785 middle and high school students were polled using the Parent-Child Relationship Scale, Adolescent Risk-taking Behavior Questionnaire, School Connectedness Scale in order to examine mechanisms underlying parent-child relationship's influence on adolescent risk-taking action. The findings revealed that (1) relationship had a considerably negative effect behavior; (2) connectedness was significant mediating variable of influencing behavior. both are predictors behavior, can behavior by...

10.54097/ehss.v8i.4627 article EN cc-by-nc Journal of Education Humanities and Social Sciences 2023-02-07

Adaptin ear-binding coat-associated protein 2 (NECAP2) belongs to the family of proteins encoding adaptin-ear-binding proteins. However, its immune effect on tumors and microenvironment are still unclear. Here, we systematically evaluated differences (variations) in NECAP2 expression for low-grade glioma (LGG) pan-cancer LGG dataset The Cancer Genome Atlas (TCGA) utilizing bioinformatics methods. We found first time that level was elevated gliomas this upregulation increased as tumor grade...

10.1155/2022/1494520 article EN cc-by Oxidative Medicine and Cellular Longevity 2022-12-07

The purpose of this study was to explore the relationship between total physical activity and different dimensions cognitive function (orientation, attention, memory) among older adults in rural Sichuan, China. This cross-sectional involved 715 (average age 72 years). Total PA measured by Physical Activity Scale for Elderly, assessed Telephone Interview Cognitive Status (TICS) questionnaire. multivariate linear regression analysis indicated that household were significantly associated with...

10.1123/japa.2022-0033 article EN Journal of Aging and Physical Activity 2022-12-19

When studying the machine vision of engineering machinery, it is found that target detection algorithm has a low rate when dealing with photos night scene. In order to solve this problem, image enhanced before entering neural network. This paper compares common gray transformation enhancement methods such as nonlinear transformation, linear logarithmic and contrast stretching. By adjusting parameters, four algorithms achieve best results in pictures dark environment. The comparative...

10.1117/12.2626557 article EN 2021-12-21
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