Lixue Lu

ORCID: 0000-0001-6168-1194
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About
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Research Areas
  • Psoriasis: Treatment and Pathogenesis
  • Cancer Immunotherapy and Biomarkers
  • IL-33, ST2, and ILC Pathways
  • Synthesis and biological activity
  • Chronic Lymphocytic Leukemia Research
  • Cancer therapeutics and mechanisms
  • Protein Degradation and Inhibitors
  • Heavy Metal Exposure and Toxicity
  • Multiple Myeloma Research and Treatments
  • Lung Cancer Treatments and Mutations
  • Microbial infections and disease research
  • Cancer Mechanisms and Therapy
  • Phytochemistry and Biological Activities
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Cytokine Signaling Pathways and Interactions
  • Advanced Radiotherapy Techniques
  • NF-κB Signaling Pathways
  • Viral-associated cancers and disorders
  • Genomics, phytochemicals, and oxidative stress
  • Biological Activity of Diterpenoids and Biflavonoids
  • Catalytic C–H Functionalization Methods
  • Synthesis and Reactivity of Heterocycles
  • Bioactive Compounds and Antitumor Agents
  • Ubiquitin and proteasome pathways
  • Synthesis and Characterization of Heterocyclic Compounds

New York Blood Center
2023-2024

Fudan University
2006-2023

China Pharmaceutical University
2019-2022

Princess Margaret Cancer Centre
2020

University of Wisconsin–Madison
2016

Virginia Commonwealth University
2006

Shanghai Medical College of Fudan University
1999-2000

Abstract Background Abdominal drainage is a standard procedure after hepatectomy, but this practice has been challenged recently. Methods Between September 2004 and March 2005, 120 consecutive patients who had undergone hepatic resection by the same surgical team were randomly allocated into no groups (60 in each group). Patient characteristics, preoperative liver function, presence of cirrhosis, resection-related factors postoperative complications compared between two groups. Results The...

10.1002/bjs.5260 article EN British journal of surgery 2006-02-20

<italic>N</italic>-(Pyridin-2-yl)amides and 3-bromoimidazo[1,2-<italic>a</italic>]pyridines were synthesized respectively from α-bromoketones 2-aminopyridine under different reaction conditions.

10.1039/c9ra06724h article EN cc-by-nc RSC Advances 2019-01-01

Purpose: Understanding inter‐observer variation is not only important for evaluating deformable image registration (DIR) which can be used to automatically transform the manual contours of a treatment plan into daily facilitating offline or online adaptive radiotherapy, but also helps physicians set reasonable margins on regions interest (ROI) when they make plans. The purpose this study determine observer Head/Neck patients using implemented radial‐difference approach and common‐area method...

10.1118/1.2240862 article EN Medical Physics 2006-06-01

The master transcription factor receptor retinoic acid receptor-related orphan γt (RORγt) regulates the differentiation of T-helper 17 (Th17) cells and production interleukin-17 (IL-17). Activation RORγt+ T in tumor microenvironment promotes immune infiltration to more effectively inhibit growth. Therefore, RORγt agonists provide a reachable approach cancer immunotherapy. Herein, series biaryl amide derivatives as novel were designed, synthesized, evaluated. Starting from reported inverse...

10.1021/acs.jmedchem.3c01492 article EN Journal of Medicinal Chemistry 2023-11-20
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