Lianyi Xu

ORCID: 0000-0001-6175-8542
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About
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Research Areas
  • Bone Tissue Engineering Materials
  • Dental Implant Techniques and Outcomes
  • Surface Modification and Superhydrophobicity
  • Organic Electronics and Photovoltaics
  • Conducting polymers and applications
  • Orthopaedic implants and arthroplasty
  • Bone Metabolism and Diseases
  • Advanced Sensor and Energy Harvesting Materials
  • Periodontal Regeneration and Treatments
  • Dental materials and restorations
  • Transition Metal Oxide Nanomaterials
  • Advanced Battery Materials and Technologies
  • Bone and Dental Protein Studies
  • Reconstructive Facial Surgery Techniques
  • Cardiac, Anesthesia and Surgical Outcomes
  • Advancements in Battery Materials
  • Supercapacitor Materials and Fabrication
  • Electrowetting and Microfluidic Technologies
  • Polydiacetylene-based materials and applications
  • Mesenchymal stem cell research
  • Antimicrobial Peptides and Activities
  • Silk-based biomaterials and applications
  • Nanomaterials and Printing Technologies
  • Electrospun Nanofibers in Biomedical Applications
  • TGF-β signaling in diseases

Wannan Medical College
2024

Zhejiang Provincial People's Hospital
2024

Hangzhou Medical College
2024

KU Leuven
2023-2024

Tongji Hospital
2020-2024

Huazhong University of Science and Technology
2020-2024

Hubei Zhongshan Hospital
2023-2024

Wuhan University
2023-2024

Shanghai Dianji University
2016-2024

Shanghai Ninth People's Hospital
2012-2021

Abstract: As one of the important ions associated with bone osseointegration, magnesium was incorporated into a micro/nanostructured titanium surface using plasma immersion ion-implantation method. Hierarchical hybrid surfaces followed by ion implantation for 30 minutes (Mg30) and hierarchical 60 (Mg60) were used as test groups. The morphology, chemical properties, amount released evaluated field-emission scanning electron microscopy, energy dispersive X-ray spectroscopy, transmission...

10.2147/ijn.s58357 article EN cc-by-nc International Journal of Nanomedicine 2014-05-01

Background: The topography of an implant surface can serve as a powerful signaling cue for attached cells and enhance the quality osseointegration. A series improved surfaces functionalized with nanoscale structures have been fabricated using various methods. Methods: In this study, H 2 O process, we two size-controllable sawtooth-like nanostructures different dimensions on titanium surface. effects nano-sawtooth rat bone marrow mesenchymal stem (BMMSCs) were evaluated without addition...

10.2147/ijn.s33575 article EN cc-by-nc International Journal of Nanomedicine 2012-08-01

Typically, bone regenerative medicine is applied to repair defects in patients with osteoporosis. Meanwhile, there an urgent need develop safe and cheap drugs that induce formation. Icariin, which reported promote the osteogenesis of stem cells vitro, main active component Herba Epimedii. However, whether icariin could caused by osteoporosis remains unknown. In this study, model rats was established ovariectomy first, then, osteogenic angiogenic differentiation mesenchymal (BMSCs) treated...

10.1038/s41598-017-05392-z article EN cc-by Scientific Reports 2017-07-05

A transparent, thermally and mechanically stable superhydrophobic coating was exploited by combining an electrodeposited PEDOT template chemical vapor depositions of TEOS POTS.

10.1039/c4ta06944g article EN Journal of Materials Chemistry A 2015-01-01

Abstract: Nanotopography modification is a major focus of interest in current titanium surface design; however, the influence nanostructured on human cell/bacterium behavior has rarely been systematically evaluated. In this study, homogeneous nanofiber structure was prepared (Nano) by alkali-hydrothermal treatment, and effects Nano behaviors MG-63 osteoblasts, gingival epithelial cells (HGECs) fibroblasts (HGFs) were evaluated comparison with smooth (Smooth) polishing micro-rough (Micro)...

10.2147/ijn.s126760 article EN cc-by-nc International Journal of Nanomedicine 2017-02-01

The monocyte/macrophage system plays an essential role in the host response and fate of endosseous implanted materials. Macrophage behavior was thought to be regulated by nanostructured titanium which has been considered as a very promising candidate for dental implants. However, there is little known subsequent effects these activated macrophages on osteogenesis angiogenesis were bone integration. Here we presented two different dimensions nanotubes generated anodic oxidation at 10 V (NT...

10.1039/c6tb03364d article EN Journal of Materials Chemistry B 2017-01-01

To evaluate the effect of ultraviolet (UV) disinfection on antibiotic-resistant Escherichia coli.Antibiotic-resistant E. coli strains were isolated from a wastewater treatment plant and subjected to UV disinfection. The antibiotic resistance profiles genes (ARGs) was evaluated by combination susceptibility analysis molecular methods. Results indicated that multiple-antibiotic-resistant (MAR) more resistant at low doses required higher dose (20 mJ cm-2 ) enter tailing phase compared with...

10.1111/jam.13480 article EN Journal of Applied Microbiology 2017-04-30

Abstract Introduction Facial scanning through smartphone applications (SSA) is increasingly being used for medical as cost‐effective, chairside method. However, clinical validation lacking. This review aims to address: (1) Which SSA could perform facial scanning? (2) can be clinically used? (3) have been reported and scientifically validated applications? Methods Technical search designed face or object was conducted on Google, Apple App Store, Google Play Store from August 2022 December...

10.1111/ocr.12821 article EN Orthodontics and Craniofacial Research 2024-06-06

Stem cell-based bone tissue engineering has been recognized as a new strategy for maxillary sinus floor elevation. More rapid formation may enhance this technique when simultaneous dental implant placement is desired. Adipose tissue-derived stem cells (ADSCs) and marrow (BMSCs) are the most well-characterized cell sources regeneration, but comparative studies on osteogenic potential of these have yielded conflicting conclusions. This study aimed to compare capacity ADSCs BMSCs in canine...

10.1177/0022034513507581 article EN Journal of Dental Research 2013-10-04

Type 1 diabetes mellitus (T1DM) is associated with a series of bone complications, which are still great challenge in the clinic. Bone marrow stromal cells (BMSCs) crucial to remodeling and attractive candidates for tissue engineering. Hence, we aimed investigate whether impaired functions BMSCs play role pathogenesis complications T1DM. were isolated from normal streptozotocin-induced diabetic rats, their proliferation osteogenic differentiation ability analyzed. Diabetic demonstrated...

10.3892/ijmm.2013.1227 article EN International Journal of Molecular Medicine 2013-01-03

An electro-responsively reversible switching of wettability between superhydrophobicity and superhydrophilicity has been obtained from a highly porous structured polythiophene film. The film was prepared by two-step electrochemical deposition on an indium tin oxide (ITO) substrate. underlying poly(3,4-ethylenedioxythiophene) (PEDOT) provides conductive support, poly(3-methylthiophene) (P(3-MTH)) deposited thereon plays the role low-surface-energy coating. this double-layer investigated...

10.1021/am5043627 article EN ACS Applied Materials & Interfaces 2014-08-12

Adipose-derived stem cells (ADSCs) with the capacity of differentiating into osteo-like have been widely investigated for bone tissue engineering as a novel seed cell source. Recombinant human platelet-derived growth factor (rhPDGF-BB) is clinically proven potential promoting proliferation and osteogenic differentiation during regeneration process. In this study, we effects rhPDGF-BB on adipogenic rat ADSCs explored whether extracellular signal-related kinase (ERK) signaling pathway might be...

10.1089/ten.tea.2013.0556 article EN Tissue Engineering Part A 2014-02-25

Intrinsic bioinertness severely hampers the application of polyetheretherketone (PEEK), although in field dentistry it is considered to be an ideal titanium substitute implanting material. In this study, a bioactive silicate coating was successfully introduced onto PEEK surface by using electron beam evaporation (EBE) technology improve its bioactivity and osseointegration PEEK. Through controlling duration EBE, incorporated amounts silicon (Si) could exquisitely adjusted obtain proper...

10.1021/acsami.5b10229 article EN ACS Applied Materials & Interfaces 2016-04-28

Circularly polarized luminescence material was fabricated by ionic binaphthol and tetraphenylethylene derivatives. Due to electrostatic interactions chiral induction, the assemblies had a helical fiber structure with high dissymmetry factor order of 10<sup>−2</sup>.

10.1039/c5tc04174k article EN Journal of Materials Chemistry C 2016-01-01

Implantation is an essential issue in orthopedic surgery. Bulk metallic glasses (BMGs), as a kind of novel materials, attract lots attentions biological field owing to their comprehensive excellent properties. Here, we show that Zr

10.1016/j.bioactmat.2021.06.018 article EN cc-by Bioactive Materials 2021-06-20

Osseointegration remains a major clinical challenge in osteoporotic patients. Strontium (Sr) has been shown to be significant therapy favor bone growth by both increasing new formation and reducing resorption. In this study, we attempt chemically functionalize Ti implants micro-arc oxidation, alkali treatment ion exchange. This functionalized surface possessed hierarchical topography with Sr incorporation, which can release ions at slow rate. To our knowledge, work is the first use type of...

10.1039/c5tb00128e article EN Journal of Materials Chemistry B 2015-01-01

A fluorescent and robust superhydrophobic coating based on a fluorinated polypyrene/silica hybrid film was prepared readily the large-scale substrates.

10.1039/c4tc02653e article EN Journal of Materials Chemistry C 2015-01-01

Abstract Objectives Curculigoside, a natural compound isolated from the medicinal plant Curculigo orchioides has been reported to prevent bone loss in ovariectomized rats. However, underlying molecular mechanisms are largely unknown. This study investigated effects of curculigoside on proliferation and osteogenic differentiation marrow stromal cells (BMSCs). Methods The toxicity, BMSCs cultured with various concentrations (0 as control, 10, 100 500 µm) were measured by viability assay, MTT...

10.1111/jphp.12054 article EN Journal of Pharmacy and Pharmacology 2013-04-30

A superhydrophobic polythiophene film (SSPTH) is prepared by double-layer electrodeposition on an indium tin oxide (ITO) glass electrode. This shows not only electroresponsive features, but also high transparency compared with the usual film. The water-droplet adhesion SSPTH can be switched between sliding and pinned states under applied potential. More intresetingly, change in results a cell adsorption low-adhesion (dedoped) films prevent Hela adhesion, whereas high-adhesion (doped) promote...

10.1002/marc.201500102 article EN Macromolecular Rapid Communications 2015-04-10

Abstract Background Due to the existence of inflammation and limited osteogenesis on precontaminated implant surface, reosseointegration is difficult realize by current therapies. Tissue‐engineering strategy has been proved quite effective in intractable bone defect situation. Purpose This study was designed see whether adoption tissue‐engineered complex adipose‐derived stem cells (ASCs) morphogenetic protein‐2 (BMP‐2) gene delivery would work efficiently correction experimental...

10.1111/cid.12308 article EN Clinical Implant Dentistry and Related Research 2016-02-29
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