A5101851200- Thyroid Disorders and Treatments
- Gestational Diabetes Research and Management
- Air Quality and Health Impacts
- Pregnancy and preeclampsia studies
- Obstructive Sleep Apnea Research
- Atmospheric chemistry and aerosols
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurosurgical Procedures and Complications
- Bone health and treatments
- Noise Effects and Management
- Bone health and osteoporosis research
- Climate Change and Health Impacts
- Vitamin D Research Studies
- Effects and risks of endocrine disrupting chemicals
- Neuroscience of respiration and sleep
- Birth, Development, and Health
- Acute Ischemic Stroke Management
- Metabolism, Diabetes, and Cancer
- Air Quality Monitoring and Forecasting
- Thyroid Cancer Diagnosis and Treatment
- Sleep and related disorders
- Gout, Hyperuricemia, Uric Acid
- Vehicle emissions and performance
- Coronary Interventions and Diagnostics
- Liver Diseases and Immunity
Chinese Academy of Medical Sciences & Peking Union Medical College
2025
Zhongshan Hospital
2025
Fudan University
2025
Peking University
2018-2024
Peking University International Hospital
2018-2024
Third Affiliated Hospital of Zhengzhou University
2021-2024
Soochow University
2020-2024
Wangjing Hospital of China Academy of Chinese Medical Sciences
2024
First Affiliated Hospital of Soochow University
2024
Third Hospital of Hebei Medical University
2023
The way that males and females react to environmental exposures negative impacts on their neurological systems is often different. Although previous research has examined the cognitively impairing effects of solitary metal exposures, relationship between mixtures cognitive function, particularly when considering an individual's sex, remains elusive. This study aimed investigate sex differences in association multiple combinations function older Americans. employed 2011-2014 NHANES survey...
The optimal strategy to treat coronary bifurcation lesions (CBL) has been a long-debated topic. combination of stent in the main vessel (MV) and drug-coated balloon (DCB) side branch (SB) seems promising, but evidence is limited. This study aims investigate novel sirolimus-coated treatment non-left CBL compared with paclitaxel-coated balloon. SPACIOUS trial prospective, non-inferiority, multicentre trial. A total 230 patients were randomised sirolimus DCB or paclitaxel group 1:1 ratio....
Abstract To build a risk prediction model of gestational diabetes mellitus using nomogram to provide simple-to-use clinical basis for the early (GDM). This study is prospective cohort including 1385 pregnant women. (1) It showed that GDM in women aged ≥ 35 years was 5.5 times higher than < 25 (95% CI: 1.27–23.73, p 0.05). In first trimester, with abnormal triglyceride who were their trimester 2.1 lipid normal 1.12–3.91, The area under ROC curve 0.728 0.683–0.772), sensitivity and...
Bariatric surgeries induce well-documented weight loss and resolve obesity comorbidities. Sexual function is one of the aspects life quality may benefit from surgery. Few studies have revealed impact bariatric on sexual in Chinese men with obesity.This a retrospective cohort study patients undergoing surgery [laparoscopic sleeve gastrectomy (LSG) or laparoscopic Roux-en-Y gastric bypass (LRYGB)]. Data were collected between September 2017 February 2022. The International Index Erectile...
to analyze the association between blood lipid metabolism and osteoporosis (OP) in older adults with type 2 diabetes mellitus (T2DM).a total of 1158 patients T2DM treated by Department Endocrinology, Peking University International Hospital, were retrospectively analyzed, including 541 postmenopausal women 617 men.(1) Levels low-density lipoprotein cholesterol (LDL-C) significantly higher OP group, while levels high-density (HDL-C) non-osteoporotic group (both p < 0.05). (2) Age, parathyroid...
Aim This study investigated whether neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte (PLR) in early pregnancy correlate with subsequent development of gestational diabetes mellitus (GDM). Methods prospective cohort enrolled 1,200 pregnant women during their first trimester at Peking University International Hospital between December 2017 March 2019. All participants underwent oral glucose tolerance testing (OGTT) 24-28 weeks gestation. Complete blood counts obtained the were...
Background Autoimmune thyroid disease (AITD) is the main cause of hypothyroidism in women childbearing age. Bisphenol A (BPA) an environmental factor affecting AITD. This study aims to investigate relationship between BPA and AITD age, thereby contributing novel evidence for prevention this specific demographic. Methods total 155 age were enrolled study, including euthyroid group comprised 60 with euthyroidism autoantibodies negativity consisted 95 at least one autoantibody positivity. The...
Introduction: This study was aimed at establishing a pregnancy-specific lipid reference interval (RI) in pregnant women single-centre the Beijing area of China, simultaneously exploring predictive value levels early pregnancy for gestational diabetes mellitus (GDM). Material and methods: From October 2017 to August 2019, Peking University International Hospital established records 1588 women, whose profiles were determined during first third trimesters. The Hoffmann technique used calculate...
Objective: This study aims to explore the correlation between free-triiodothyronine (FT3)-to-free-thyroxine (FT4) ratio (FT3/FT4) and diabetic kidney disease (DKD) in patients with type 2 diabetes mellitus (T2DM). Methods: retrospectively analyzed 1729 T2DM hospitalized Department of Endocrinology, Peking University International Hospital, from January 2017 August 2021, including 1075 males 654 females. In accordance FT3/FT4, were divided into three groups. Results: (1) The levels...
Association between ambient air pollution and congenital heart diseases (CHDs) remains inconclusive, the critical exposure windows has not been well studied.This case-control study aimed to assess effect of on risk CHDs subtypes in Henan, China, further explore potential susceptible windows.Daily average particulate matter with an aerodynamic diameter ≤2.5 µm (PM2.5) ≤10 (PM10), nitrogen dioxide (NO2), sulfur (SO2), carbon monoxide (CO) ozone (O3) were collected by Chinese Air Quality...
Purpose: To explore the association between thyroid parameters and subclinical atherosclerosis (AS) in hospitalised euthyroid patients with type 2 diabetes mellitus (T2DM). Patients Methods: A retrospective analysis was conducted involving 1245 inpatients T2DM. Free triiodothyronine (FT3), free thyroxine (FT4), stimulating hormone (TSH) levels were measured, carotid artery ultrasonography performed. Thyroid (TH) sensitivity evaluated using feedback quantile-based index (TFQI), TSH (TSHI),...
Background: For patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) and type 2 diabetes mellitus (T2DM), the night interruption intermittent hypoxia due to apnea or hypopnea may induce glycemic excursions reduce insulin sensitivity. This study aimed investigate effect of continuous positive airway pressure (CPAP) therapy in OSAHS T2DM. Methods: Continuous glucose monitoring system (CGMS) was used 40 T2DM newly diagnosed OSAHS. The measurements were repeated after 30 days CPAP...
Abstract This study aimed to analyze the clinical characteristics of lower extremity atherosclerotic disease (LEAD) in Chinese adult type 2 diabetes (T2D) patients, and also explored risk factors for LEAD developed simple-to-use nomograms lesion degree these patients. We retrospectively studied 4422 patients (male = 2084; female 2338) with T2D who were ≥50. Based on arterial ultrasound findings, we divided into three groups: normal, mild, moderate-to-severe group. The related analyzed by...
To analyze the association between uric acid levels and bone mineral density in postmenopausal women with type 2 diabetes mellitus. We retrospectively analyzed 262 mellitus, to assess using T score of dual-energy X-ray absorptiometry. (1) Women osteoporosis group demonstrated higher lower estimated glomerular filtration rate (p < 0.05, respectively). (2) Uric were positively correlated hip lumbar spine (r = 0.17, p 0.05; r 0.25, 0.28, Meanwhile, there was a positive relation 0.22, 0.05). (3)...
Clinically, the renin-angiotensin-aldosterone system is activated intensely in patients with moderate to severe traumatic brain injury (TBI). Increased angiotensin II circulatory blood after TBI can enter through disrupted blood-brain barrier. Angiotensin-converting enzyme 2 (ACE2) an that metabolizes into (1-7), which has been shown have neuroprotective results. The expression and role of ACE2 remains elusive, however. We found protein abundance was downregulated around contusional area...
Abstract Purpose This study aimed to investigate the effect of continuous positive airway pressure (CPAP) on blood glucose fluctuation in patients with type 2 diabetes mellitus (T2DM) and obstructive sleep apnea (OSA). Methods Patients T2DM OSA were divided into an intervention group a control group. All treatment naïve. The was given CPAP therapy. subjects monitored using monitoring system (CGMS) for weeks. Results Of 60 patients, 30 selected receive while without served as controls....
To evaluate the effects of serum thyroid hormone levels on advanced liver fibrosis in cases with NAFLD (non-alcoholic fatty disease) and T2DM (type 2 diabetes mellitus).A total 1422 who were admitted to Peking University International Hospital between December 2014 October 2019 retrospectively analyzed. Standard anthropometry as well clinical laboratory evaluation performed all patients. Abdominal ultrasonography was diagnose NAFLD. NFS (NAFLD score) used identify patients NAFLD.In NAFLD,...