- Plant Stress Responses and Tolerance
- Plant Molecular Biology Research
- Ultrasonics and Acoustic Wave Propagation
- Plant nutrient uptake and metabolism
- Flood Risk Assessment and Management
- Protein Kinase Regulation and GTPase Signaling
- Computational Drug Discovery Methods
- Non-Destructive Testing Techniques
- Nuclear Receptors and Signaling
- Dam Engineering and Safety
- Advanced Memory and Neural Computing
- Hydropower, Displacement, Environmental Impact
- Geophysical Methods and Applications
Shanghai East Hospital
2024
Hunan University
2024
Huazhong Agricultural University
2024
North China Electric Power University
2022
Advanced Lightweight Engineering (Netherlands)
2019
Glycogen synthase kinase-3β (GSK-3β) has been identified to promote inflammation and its inhibitors have also proven treat some inflammatory-mediated diseases in animal models. Allosteric inherently better therapeutical value due their higher specificity than ATP-competitive ones. In this paper, we reported the discovery of a novel series N, N-dibenzylcinnamamide (DBCA) compounds as allosteric GSK-3β via scaffold hopping strategy. The vitro enzymatic evaluation showed most DBCA derivatives...
ABSTRACT The phospholipase Ds (PLDs) are crucial for cellular signalling and play roles in plant abiotic stress response. In this study, we identified 12 PLD genes from the genome data of perennial ryegrass ( Lolium perenne ), which is widely used as forage turfgrass. Among them, LpPLDδ3 was significantly repressed by ABA treatment, induced drought heat treatments. ectopic overexpression (OE) Arabidopsis enhanced tolerance to osmotic demonstrated an increased survival rate reduced...
With the increase of economic strength and technological advancement, financial technical issues are becoming less constraining for construction water conservancy hydropower projects, resettlement reservoir resettlers has become most critical factor in determining success or failure construction. This study constructs a risk analysis framework resettlers’ livelihood strategy transformation from perspective “resilient livelihoods”, characterizing their exposure with comprehensive index...
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