A5024428654- Genital Health and Disease
- Urologic and reproductive health conditions
- Urological Disorders and Treatments
- Prostate Cancer Diagnosis and Treatment
- Cutaneous Melanoma Detection and Management
- Cervical Cancer and HPV Research
- Prostate Cancer Treatment and Research
- Renal cell carcinoma treatment
- Bladder and Urothelial Cancer Treatments
- Cancer Diagnosis and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Colorectal and Anal Carcinomas
- Head and Neck Cancer Studies
- Breast Cancer Treatment Studies
- Nonmelanoma Skin Cancer Studies
- Medical Imaging Techniques and Applications
- Female Genital Mutilation/Cutting Issues
- Lung Cancer Diagnosis and Treatment
- Ethics and Legal Issues in Pediatric Healthcare
- Testicular diseases and treatments
- Renal and related cancers
- Radiomics and Machine Learning in Medical Imaging
- Ovarian cancer diagnosis and treatment
- Sarcoma Diagnosis and Treatment
- Sexual function and dysfunction studies
The Netherlands Cancer Institute
2013-2024
Leiden University Medical Center
2013-2023
Haga Hospital
2018
Melanoma Institute Australia
2016
Hospital Universitario Virgen Macarena
2014
University of Maryland, Baltimore
2012
The purpose of this study was to compare the lymphoscintigraphic drainage patterns a hybrid sentinel node tracer consisting fluorescent dye indocyanine green (ICG) and <sup>99m</sup>Tc-nanocolloid with pattern alone, current standard in many European countries. <b>Methods:</b> Twenty-five patients melanoma head neck region (<i>n</i> = 10), on trunk 6), or penile carcinoma 9) who were scheduled for biopsy prospectively included. First, procedure performed. After injection at lesion site,...
This study was designed to examine the feasibility of combining lymphoscintigraphy and intraoperative sentinel node identification in patients with head neck melanoma by using a hybrid protein colloid that is both radioactive fluorescent. Eleven scheduled for biopsy region were studied. Approximately 5 h before surgery, nanocolloid labeled indocyanine green (ICG) technetium-99m (99mTc) injected intradermally four deposits around scar primary excision. Subsequent single photon emission...
Purpose To evaluate the hybrid approach in a large population of patients with melanoma head and neck, on trunk, or an extremity who were scheduled for sentinel node (SN) biopsy. Materials Methods This prospective study was approved by institutional review board. Between March 2010 2013, 104 melanoma, including 48 women (average age, 54.3 years; range, 18.5–87.4 years) 56 men 55.2 22.4–77.4 (P = .76) enrolled after obtaining written informed consent. Following intradermal tracer...
Patients with advanced penile squamous cell carcinoma have a poor prognosis (21% 2-year overall survival [OS] from diagnosis). We assessed the activity of atezolizumab (anti-PD-L1) in patients cancer, or without radiotherapy (RT).A single-center, nonrandomized phase II study two treatment arms was conducted 32 histologically confirmed cancer. All received (1,200 mg) once every 3 weeks. Twenty patients, who were expected to benefit RT for locoregional disease control, additional irradiation....
Hybrid tracers that are both radioactive and fluorescent help extend the use of fluorescence-guided surgery to deeper structures. Such hybrid facilitate preoperative surgical planning using (3D) scintigraphic images enable synchronous intraoperative radio- fluorescence guidance. Nevertheless, we previously found improved orientation during laparoscopic remains desirable. Here illustrate how navigation based on optical tracking a endoscope may further improve accuracy After feeding SPECT/CT...
Objective To evaluate penile squamous cell carcinoma (PSCC) incidence and centralisation trends in the Netherlands over past three decades, as well effect of PSCC care on survival. Patients methods In is largely centralised one national centre expertise (Netherlands Cancer Institute [NCI], Amsterdam). For this study, Registry, an independent nationwide cancer registry, provided per‐patient data age, clinical pathological tumour staging, follow‐up, vital status. with treatment at NCI were...
Our objective was to determine the diagnostic capabilities of combined prostate-specific membrane antigen (PSMA) PET/CT and sentinel node (SN) biopsy in PSMA PET/CT–negative patients for primary lymph (LN) staging prostate cancer (PCa) patients. <b>Methods:</b> Between January 2017 March 2019, retrospectively, all consecutive with diagnosed intermediate- or high-risk PCa who underwent preoperative (<sup>68</sup>Ga <sup>18</sup>F-DCFPyL) followed by robot-assisted radical prostatectomy...
Intraprostatic injection of the hybrid tracer indocyanine green (ICG)–<sup>99m</sup>Tc-nanocolloid enables both preoperative sentinel node (SN) identification and intraoperative visualization SN. Relating fluorescence deposits in embedded prostate tissue specimens to preoperatively detected SNs also provides opportunity study influence their placement on lymphatic drainage pattern. <b>Methods:</b> Nineteen patients with carcinoma scheduled for robot-assisted laparoscopic prostatectomy lymph...
We explored the clinical feasibility and accuracy of intraoperative navigation based on preoperatively acquired 3-dimensional functional imaging data.Ten patients with penile carcinoma scheduled for sentinel node biopsy were prospectively included in study. After tracer injection preoperative single photon emission computerized tomography/computerized tomography was performed a reference target fixed patient. Repositioning sterile shortly before surgery allowed mixed reality γ probe (also...
This Q&A is derived from recommendations in EAU-ASCO Collaborative Guideline on Penile Cancer: 2023 Update.This document based an