A5089747788- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- Meat and Animal Product Quality
- Hemophilia Treatment and Research
- Ruminant Nutrition and Digestive Physiology
- Cancer-related gene regulation
- Animal Genetics and Reproduction
- Lipid metabolism and biosynthesis
- Muscle Physiology and Disorders
- Animal Nutrition and Physiology
- Cancer-related molecular mechanisms research
- Peroxisome Proliferator-Activated Receptors
- Adipose Tissue and Metabolism
- Mast cells and histamine
- CRISPR and Genetic Engineering
- Infectious Diseases and Mycology
- Veterinary Oncology Research
- Fatty Acid Research and Health
- Chromosomal and Genetic Variations
- Animal health and immunology
- Antioxidant Activity and Oxidative Stress
- Viral gastroenteritis research and epidemiology
- RNA and protein synthesis mechanisms
- Neurogenetic and Muscular Disorders Research
- Microbial Metabolic Engineering and Bioproduction
The University of Adelaide
2014-2025
Cooperative Research Centre for Beef Genetic Technologies
2006-2014
Commonwealth Scientific and Industrial Research Organisation
2001
South Australian Museum
2001
Health Sciences and Nutrition
2001
Australian Wine Research Institute
2001
Mayo Clinic
1989-1993
WinnMed
1990
Stanford University
1986
Oregon State University
1978-1985
Abstract We describe the organization of a nascent international effort, Functional Annotation Animal Genomes (FAANG) project, whose aim is to produce comprehensive maps functional elements in genomes domesticated animal species.
The fatty acid composition of the triacylglycerol fraction shoulder fat from Limousin and Jersey yearling heifers, steers, non-lactating cows was investigated. Significant breed differences in degree saturation were apparent between cows, but not observed yearlings. had less saturated acids than Limousin. showed an increased percentage monounsaturated compared with In contrast, level same as calculated indices enzyme activities also differed breeds. higher Δ9-desaturase elongase This...
Mature Hereford cows (766) were mated to 97 sires from seven breeds (Jersey, Wagyu, Angus, Hereford, South Devon, Limousin, and Belgian Blue), resulting in 1,215 calves born over 4 yr (1994 1997). These cattle comprised Australia's "Southern Crossbreeding Project." Heifers slaughtered at an average of 16 mo with hot standard carcass weight 219 kg 9 mm fat the rump. Steers 23 319 13 Meat samples taken on day after slaughter for subsequent laboratory analysis i.m. content fatty acid...
This study investigated the effects of a SNP in myostatin gene (MSTN or growth differentiation factor 8, GDF8) on birth, growth, carcass, and beef quality traits Australia (Aust.) New Zealand (NZ). The is cytosine to adenine transversion exon 1, causing an amino acid substitution leucine for phenylalanine(94) (F94L). experiment used crosses between Jersey Limousin breeds, with design being backcross using first-cross bulls x breeding, mated cows. Progeny were genotyped phenotyped Aust.,...
We investigated the fatty acid composition of phospholipid fraction shoulder muscle (triceps brachii) from Jersey and Limousin yearling steers, heifers, nonlactating cows. The aim was to study breed, sex, age differences. Significant breed differences in some individual acids were apparent between cows had more palmitate, vaccenate, arachidonate, less gammalinolenate eicosapentanoate than Age significant: proportions stearate, oleate decreased linoleate, total polyunsaturates increased with...
Summary Single nucleotide polymorphisms (SNPs) in the calpain 1 ( CAPN1 ) and calpastatin CAST genes were studied to determine their effects on meat tenderness Bos taurus cattle. Strip loins (M. longissimus dorsi) removed from cattle four resource populations after slaughter n = 1042), aged under controlled conditions until fixed times rigor mortis, cooked measured using a tenderometer. Animals genotyped for SNP c.947C>G (p.Ala316Gly; AF252504 c.2959A>G AF159246 ). Frequencies of C...
Green tea from Camellia sinensis lowers plasma cholesterol in animal models of hypercholesterolemia. The aim this study was to determine the effects green on expression hepatic low-density lipoprotein (LDL) receptor, a cell surface protein involved control cholesterol. Incubating human HepG2 liver cells culture with increased both LDL receptor binding activity and protein. An ethyl acetate extract tea, containing 70% (w/w) catechins, also activity, protein, mRNA, indicating that (1) effect...
In this study, a highly significant quantitative trait locus (QTL) for meat percentage, eye muscle area (EMA) and silverside percentage was found on cattle chromosome 2 at 0-15 cM, region containing the positional candidate gene growth differentiation factor 8 (GDF8), which has common alias myostatin (MSTN). Loss-of-function mutations in MSTN are known to cause an extreme 'double muscling' phenotype cattle. associations of with carcass traits were using maternally inherited haplotypes from...
Ovine hereditary chondrodysplasia, or spider lamb syndrome (SLS), is a genetic disorder that characterized by severe skeletal abnormalities and has resulted in substantial economic losses for sheep producers. Here we demonstrate non-synonymous T>A transversion the highly conserved tyrosine kinase II domain of positional candidate gene, fibroblast growth factor receptor 3 (FGFR3), responsible SLS. We also mutant FGFR3 allele an additive effect on long-bone length, calling into question...
Various nystatin-resistant mutants defective in S-adenosylmethionine: delta 24-sterol-C-methyltransferase (EC 2.1.1.41) were shown to possess alleles of the same gene, erg6. The genetic map location erg6 was be close trp1 on chromosome 4. Despite single locus for erg6, enzyme activity found three separate fractions: mitochondria, microsomes, and "floating lipid layer." amount each fraction could manipulated by assay conditions. lipids synthesis Saccharomyces cerevisiae compared with a C5(6)...
beta, beta-carotene-9', 10'-dioxygenase (BCO2) plays a role in cleaving beta-carotene eccentrically, and may be involved the control of adipose milk colour cattle. The bovine BCO2 gene was sequenced as potential candidate for beef fat QTL on chromosome (BTA) 15. A single nucleotide base change located exon 3 causes substitution stop codon (encoded by allele) tryptophan(80) G (c. 240G>A, p.Trp80stop, referred to herein SNP W80X). Association analysis showed significant differences...
Residual feed intake (RFI) is the difference between an animal’s actual and that which would be expected based on production. This experiment was to test hypothesis part of variation in RFI may due differences energetic efficiency through changes heat production, these being protein metabolism. Following three generations divergent selection for RFI, eight High Low-RFI heifers were fed at both 105% 180% predicted maintenance requirements. Between-RFI line feeding-level assessed energy...