Muhammad Sajid

ORCID: 0000-0001-6274-429X
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About
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Research Areas
  • Advanced battery technologies research
  • Advanced Battery Materials and Technologies
  • SARS-CoV-2 detection and testing
  • SARS-CoV-2 and COVID-19 Research
  • Covalent Organic Framework Applications
  • Advanced Battery Technologies Research
  • Biosensors and Analytical Detection
  • Hepatitis Viruses Studies and Epidemiology
  • Acute Ischemic Stroke Management
  • CRISPR and Genetic Engineering
  • Metal-Organic Frameworks: Synthesis and Applications
  • Hepatitis B Virus Studies
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Chemical Synthesis and Reactions
  • Hepatitis C virus research
  • Electrocatalysts for Energy Conversion
  • Ultrasound in Clinical Applications
  • RNA Interference and Gene Delivery
  • COVID-19 diagnosis using AI
  • Microbial Metabolism and Applications
  • Luminescence Properties of Advanced Materials
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Neurosurgical Procedures and Complications
  • Vitamin C and Antioxidants Research
  • Poxvirus research and outbreaks

University Hospitals Birmingham NHS Foundation Trust
2025

National Health Service
2025

University Hospitals Coventry and Warwickshire NHS Trust
2025

Benazir Bhutto Hospital
2025

International Islamic University, Islamabad
2025

University of Science and Technology of China
2022-2024

Hefei National Center for Physical Sciences at Nanoscale
2023-2024

Chinese Academy of Sciences
2023

Wuhan University
2020-2021

Alfaisal University
2021

Quantitative real time PCR (RT-PCR) is widely used as the gold standard for clinical detection of SARS-CoV-2. However, due to low viral load specimens and limitations RT-PCR, significant numbers false negative reports are inevitable, which results in failure timely diagnose, cut off transmission, assess discharge criteria. To improve this situation, an optimized droplet digital (ddPCR) was SARS-CoV-2, showed that limit ddPCR significantly lower than RT-PCR. We further explored feasibility...

10.1080/22221751.2020.1772678 article EN cc-by Emerging Microbes & Infections 2020-01-01

Abstract The aqueous zinc‐iodine battery is a promising energy storage device, but the conventional two‐electron reaction potential and density of iodine cathode are far from meeting practical application requirements. Given that rich in redox reactions, activating high‐valence has become research direction for developing high‐voltage batteries. In this work, by designing multifunctional electrolyte additive trimethylamine hydrochloride (TAH), stable four‐electron‐transfer I − /I 2 +...

10.1002/anie.202404784 article EN Angewandte Chemie International Edition 2024-06-13

Hepatitis B virus is an enveloped DNA virus, that infects more than three hundred and sixty million people worldwide leads to severe chronic liver diseases. Interferon-alpha inducible protein 6 (IFI6) IFN-stimulated gene (ISG) whose expression highly regulated by the stimulation of type I IFN-alpha restricts various kinds infections targeting different stages viral life cycle. This study aims investigate antiviral activity IFI6 against HBV replication expression. The was induced IFN-α in...

10.3389/fimmu.2021.634937 article EN cc-by Frontiers in Immunology 2021-04-01

Hydrogen-chlorine (H2-Cl2) fuel cells have distinct merits due to fast electrochemical kinetics but are afflicted by high cost, low efficiency, and poor reversibility. The development of a rechargeable H2-Cl2 battery is highly desirable yet challenging. Here, we report operating statically in wide temperature ranging from -70 40 °C, which enabled reversible Cl2/Cl- redox cathode an electrocatalytic H2 anode. A hierarchically porous carbon designed achieve effective Cl2 gas confinement...

10.1021/jacs.3c09819 article EN Journal of the American Chemical Society 2023-10-25

Abstract Real time fluorescent quantitative PCR (RT-PCR) is widely used as the gold standard for clinical detection of SARS-CoV-2. However, due to low viral load in patient throats and limitations RT-PCR, significant numbers false negative reports are inevitable, which results failure timely diagnose, early treat, cut off transmission, assess discharge criteria. To improve this situation, an optimized droplet digital (ddPCR) was SARS-CoV-2, showed that limit ddPCR significantly lower than...

10.1101/2020.02.29.20029439 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2020-03-06

Aqueous proton batteries (APBs) have emerged as one of the most promising for large-scale energy storage technology. However, they usually show an undesirable electrochemical performance. Herein, we demonstrate a novel aqueous catalytic hydrogen gas powered organic (HOP) battery, which is driven by evolution/oxidation redox reactions via commercial nanocatalysts on anode and coordination/decoordination C═O with H+ cathode. The HOP battery shows excellent rate capacity 190.1 mAh g-1 at 1 A...

10.1021/acs.nanolett.3c01304 article EN Nano Letters 2023-08-28

Abstract The aqueous zinc‐iodine battery is a promising energy storage device, but the conventional two‐electron reaction potential and density of iodine cathode are far from meeting practical application requirements. Given that rich in redox reactions, activating high‐valence has become research direction for developing high‐voltage batteries. In this work, by designing multifunctional electrolyte additive trimethylamine hydrochloride (TAH), stable four‐electron‐transfer I − /I 2 +...

10.1002/ange.202404784 article EN Angewandte Chemie 2024-06-13

Background One of the main risk factors for coronary artery disease (CAD), which is a significant source morbidity and death, diabetes mellitus (DM), also speeds up disease's course severity. This study aimed to compare severity CAD between diabetic non-diabetic patients, providing insights guide clinical decision-making improve therapeutic outcomes. Methodology A prospective, observational was conducted at Sheikh Mohamed Bin Zayed Al Nahyan Institute Cardiology, Quetta, from August 2018...

10.7759/cureus.77344 article EN Cureus 2025-01-12

Despite the availability of effective vaccines, hepatitis B virus (HBV) is still a major health issue, and approximately 350 million people have been chronically infected with HBV throughout world. Interferons (IFNs) are key molecules in innate immune response that restrict several kinds viral infections via induction hundreds IFN-stimulated genes (ISGs). The objective this study was to confirm if interferon alpha-inducible protein 27 (IFI27) as an ISG could inhibit gene expression DNA...

10.3389/fmicb.2021.656353 article EN cc-by Frontiers in Microbiology 2021-03-31

Introduction: Coronavirus disease 2019 (COVID-19) is a global pandemic with significant morbidity and mortality. The Saudi government adopted mandatory home quarantine curfew hours for all residents, excluding essential service workers. During the lockdown, public's fear of infection can adversely impact mental health, causing psychological distress. objective this research to assess frequency depression obsessive-compulsive disorder (OCD) among general population during COVID-19 in Arabia....

10.7759/cureus.12978 article EN Cureus 2021-01-28

Curative therapies for chronic hepatitis B virus (HBV) infection remain a distant goal, and the persistence of stable covalently closed circular DNA (cccDNA) during HBV replication is key barrier that hard to break through using drugs currently approved treatment. Due accuracy, efficiency, cost-effectiveness genome editing, CRISPR/Cas technologies are being widely used gene therapy in antiviral strategies. Although could possibly clear cccDNA, ensuring its safety requirement application. In...

10.3389/fmicb.2021.665184 article EN cc-by Frontiers in Microbiology 2021-06-26

Background: In the scenario of, inadequate testing, low sensitivity of COVID-19-PCR test, limited availability testing kits, and detection rate, we aimed to investigate usefulness high-resolution computed tomography chest (HRCT) for diagnosing pandemic coronavirus (COVID-19) pneumonia.
 Objective: To determine diagnostic efficacy HRCT thorax in Covid-19 Materials Methods: This prospective, cross-sectional study was conducted Pulmonology–OPD Gulab Devi Teaching Hospital, Lahore-Pakistan...

10.37939/jrmc.v24isupp-1.1443 article EN cc-by-sa Journal of Rawalpindi Medical College 2020-08-13

Graphical Abstract An amine-functionalized covalent organic framework with catalytic activity is demonstrated to significantly decrease the oxidation barrier and accelerate kinetics of LiCl in a rechargeable Li-Cl2 battery. The developed battery exhibits low overpotential ultrahigh discharge capacity good stability wide temperature range, as reported by Wei Chen, Shenxiang Zhang et al. their Research Article (e202315931).

10.1002/ange.202400470 article EN Angewandte Chemie 2024-01-18

Abstract Rechargeable Li−Cl 2 battery is a promising high energy density system. However, reasonable cycle life could only be achieved under low specific capacities due to the sluggish oxidation of LiCl Cl . Herein, we propose an amine‐functionalized covalent organic framework (COF) with catalytic activity, namely COF−NH , that significantly decreases barrier and accelerates kinetics in cell. The resulting cell using (Li−Cl @COF−NH ) simultaneously exhibits overpotential, ultrahigh discharge...

10.1002/ange.202315931 article EN Angewandte Chemie 2023-12-05

Background: Pyogenic liver abscess (PLA) is a rare but life-threatening disease, with frequency ranging from 10.83 to 17.45 per 100,000 persons. The major cause of PLA bacterial infection parenchyma. present research study was designed investigate the common microbes causing in Peshawar (Pakistan) and evaluate variety most capable efficient antibiotics for treatment PLA. Methods: A 7-year (2012 - 2018) retrospective demographic medical records all patients (n = 379) admitted Hayatabad...

10.15419/bmrat.v7i12.656 article EN Biomedical Research and Therapy 2020-12-31

Lanthanide-based Upconverting nanoparticles (UCNPs) gained huge attention owing to their distinctive photonic properties. By dry transfer method, the almost ideal interface between graphene and MoS2 was attained. The optical properties of these materials were greatly affected by stacking them together proceeded UCNPs doping. Emission band MoS2, heterostructure expanded UCNPs. A novel photodetector successfully fabricated integrating with a graphene/MoS2 heterostructure, resulting in...

10.2139/ssrn.4555617 preprint EN 2023-01-01
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