A5032205506- Circadian rhythm and melatonin
- Research on Leishmaniasis Studies
- Tryptophan and brain disorders
- COVID-19 and Mental Health
- Global Cancer Incidence and Screening
- Immunotherapy and Immune Responses
- BRCA gene mutations in cancer
- Enzyme Catalysis and Immobilization
- Trypanosoma species research and implications
- Autism Spectrum Disorder Research
- Pesticide and Herbicide Environmental Studies
- Sleep and related disorders
- Stress Responses and Cortisol
- Pharmacological Effects and Toxicity Studies
- Urinary Tract Infections Management
- Genetics and Neurodevelopmental Disorders
- Health and Wellbeing Research
- RNA Interference and Gene Delivery
- Epilepsy research and treatment
- Inflammasome and immune disorders
- Escherichia coli research studies
- vaccines and immunoinformatics approaches
- Thermography and Photoacoustic Techniques
- Essential Oils and Antimicrobial Activity
- Childhood Cancer Survivors' Quality of Life
Sabzevar University of Medical Sciences
2013-2023
Mashhad University of Medical Sciences
2017
Tarbiat Modares University
2015
North Khorasan University of Medical Sciences
2015
Autism spectrum disorder (ASD) is a constellation of neurodevelopmental disorders with high phenotypic and genetic heterogeneity, complicating the discovery causative genes. Through forward genetics approach selecting for defective vocalization in mice, we identified Kdm5a as candidate ASD gene. To validate our discovery, generated knockout mouse model ( -/- ) confirmed that inactivating disrupts vocalization. In addition, mice displayed repetitive behaviors, sociability deficits, cognitive...
Introduction This study is an effort to diagnose breast cancer by processing the quantitative and qualitative information obtained from medical infrared imaging. The imaging free any harmful radiation it one of best advantages proposed method. By analyzing this information, diagnostic parameters among available are selected its sensitivity precision in diagnosis improved utilizing genetic algorithm artificial neural network. Materials Methods In research, necessary thermal 200 people, 8...
To determine the potential antibacterial activity of ethyl acetate and aqueous extracts from Mentha longifolia L. (M. longifolia) hydroalcoholic extract Zataria multiflora Boiss. (Z. multiflora) against important human pathogens.Pseudomonas aeruginosa, Shigella dysenteriae, Klebsiella pneumoniae (K. pneumonia), Enterobacter cloacae, Salmonella typhi, Proteus mirabilis, Serratia marcescens, Bacillus cereus, Staphylococcus saprophyticus aureus were kinds pathogenic bacteria to effect M. Z....
The acyl-CoA-binding domain-containing protein 6 (ACBD6) is ubiquitously expressed, plays a role in the acylation of lipids and proteins regulates N-myristoylation via N-myristoyltransferase enzymes (NMTs). However, its precise function cells still unclear, as consequence ACBD6 defects on human pathophysiology. Using exome sequencing extensive international data sharing efforts, we identified 45 affected individuals from 28 unrelated families (consanguinity 93%) with bi-allelic pathogenic,...
Abstract Aim: To evaluate the clinical efficacy of adjuvant use melatonin in patients with coronavirus disease 2019 (COVID-19). Methods: This single-center, double-blind, randomized trial included 74 hospitalized confirmed mild to moderate COVID-19 at Baqiyatallah Hospital Tehran, Iran, from April 25, 2020 June 5, 2020. Patients were randomly assigned a 1:1 ratio receive standard care and plus dose 3 mg three times daily for 14 days. Clinical characteristics, laboratory, radiological...
The inflammasome as a multiprotein complex has role in activating ASC and caspase-1 resulting IL-1β various infections diseases like corona virus infection tissues. It was shown that these tissues are affected by COVID-19 patients. According to the current evidence, melatonin is not veridical while possessing high safety profile, however, it possesses indirect anti-viral actions owing its anti-oxidation, anti-inflammation, immune improving properties. This study aims assess impacts of...
Organophosphorus hydrolase (OPH) is a type of organophosphate-degrading enzyme which widely used in the bioremediation process.In this study, periplasmic and cytoplasmic productions activity recombinant OPH Escherichia coli were investigated compared using two pET systems (pET21a pET26b).The sequence encoding opd gene was synthesized expressed form inclusion body pET21a-opd space pET26b-opd.Sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) analysis showed band about 37 kDa...
Background and Objective:Regarding the prevalence of premature dental caries in childhood role asthma as a risk factor for increased vulnerability to caries, present study aimed determine compare frequency between asthmatic children under treatment with inhaled corticosteroids healthy children.Methodology:In this case-control study, 70 who were taking corticosteroid sprays at least one year aged 3-12 visiting clinic or office pediatricians 2017-2018 selected sample based on convenient...
Background: This study was aimed at evaluating the effect of ursodeoxycholic acid (UDCA) and multistrain synbiotic on indirect hyperbilirubinemia among neonates treated with phototherapy. Materials Methods: double-blind, randomized clinical trial conducted 120 subjects presenting in 2019. Subjects were randomly divided into three groups synbiotic, UDCA, control. The group received five drops/day addition to UDCA 10 mg/kg/day Ursobil every 12 h Control a placebo (water) Phototherapy...