A5006068307- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- Hydrological Forecasting Using AI
- Advanced Technologies in Various Fields
- COVID-19 Clinical Research Studies
- Flood Risk Assessment and Management
- Respiratory Support and Mechanisms
- Infectious Encephalopathies and Encephalitis
- Cardiovascular and Diving-Related Complications
Instituto de Biomedicina de Sevilla
2020-2023
Universidad de Sevilla
2020-2023
Hospital Universitario Virgen del Rocío
2020-2023
Mapúa University
2023
Abstract The protective efficacy of vaccines against SARS-CoV-2 infection in the brain is yet unclear. Here, susceptible transgenic K18-hACE2 mouse model severe COVID-19 disease, we report a detailed spatiotemporal description and replication different areas brain. Remarkably, occurs primarily neurons, producing important neuropathological alterations such as neuronal loss, incipient signs neuroinflammation, vascular damage infected mice. Notably, one or two doses modified vaccinia virus...