A5084264883- Gold and Silver Nanoparticles Synthesis and Applications
- Nanocluster Synthesis and Applications
- Molecular Junctions and Nanostructures
- Nanoparticle-Based Drug Delivery
- Polymer Surface Interaction Studies
- Quantum Dots Synthesis And Properties
- Advanced biosensing and bioanalysis techniques
- Nanomaterials for catalytic reactions
- Hydrogels: synthesis, properties, applications
- Nanoparticles: synthesis and applications
- Advanced Sensor and Energy Harvesting Materials
- Electrospun Nanofibers in Biomedical Applications
- Electrochemical Analysis and Applications
- Luminescence Properties of Advanced Materials
- Carbon and Quantum Dots Applications
- Nanoplatforms for cancer theranostics
- Pickering emulsions and particle stabilization
- Advanced Nanomaterials in Catalysis
- Solid State Laser Technologies
- Nanofabrication and Lithography Techniques
- Click Chemistry and Applications
- Inorganic Fluorides and Related Compounds
- Laser-Ablation Synthesis of Nanoparticles
- Surface Modification and Superhydrophobicity
- Wound Healing and Treatments
University of Almería
2008-2024
Universidad Complutense de Madrid
2019-2023
Universidad de Málaga
2014-2022
Hospital San Juan de la Cruz
2022
Leibniz Institute of Polymer Research
2012-2018
Centro Médico Sanitas Málaga
2016
University of Houston
2013-2015
Universidade de Vigo
2009-2011
Caught in a trap: Colloids of gold nanoparticles coated with thermally responsive poly-(N-isopropylacrylamide) (pNIPAM) microgel can trap molecules different ways as function temperature (see scheme). The porous pNIPAM shells prevent electromagnetic coupling between metal particles, thus providing highly reproducible surface-enhanced Raman scattering (SERS) signals and intensity. Detailed facts importance to specialist readers are published "Supporting Information". Such documents...
Gold nanoparticles are encapsulatedwithin thermoresponsive pNIPAMmigrogels through an easy two-stepprotocol. The core/shell structure ofthe composite is characterized by TEM,AFM, PCS, and UV-vis spectroscopy. restricted environment thehigh porosity of the microgel shell arestudied overgrowth thegold core. Supporting information for this article available on WWW under http://www.wiley-vch.de/contents/jc_2089/2008/adma200800064_s.pdf or from author. Please note: publisher not responsible...
We studied the controlled growth of triangular prismatic Au nanoparticles with different beveled sides for surface-enhanced Raman spectroscopy (SERS) applications. First, in a seedless synthesis using 3-butenoic acid (3BA) and benzyldimethylammonium chloride (BDAC), gold nanotriangles (AuNTs) were synthesized mixture nanooctahedra (AuNOCs) separated by depletion-induced flocculation. Here, influence temperature, pH, reducing agent on reaction kinetics was initially investigated UV-vis...
Abstract Thermoresponsive nanocomposites comprising a gold nanoparticle core and poly( N ‐isopropylacrylamide) (pNIPAM) shell are synthesized by grafting the surface with polystyrene, which allows coating of an inorganic organic shell. Through careful control experimental conditions, pNIPAM cross‐linking density can be varied, in turn its porosity stiffness, as well thickness from few to hundred nanometers is tuned. The characterization these core–shell systems carried out photon‐correlation...
The thermoresponsive optical properties of Au nanorod-doped poly(N-isopropylacrylamide) (Au NR-pNIPAM) microgels with different NR payloads and aspect ratios are presented. Since the volume phase transition pure pNIPAM is reversible, response reversibility NR-pNIPAM hybrids systematically analyzed. Besides, extinction cross-section near-field enhancement simulations for NR-microgel performed using a new numerical method based on surface integral equation moments formulation (M3 solver)....
A novel wet-chemical protocol is reported for the synthesis of "temperature-programmable" catalytic colloids consisting bimetallic core@shell AuAg nanoparticles encapsulated into poly(N-isopropylacrylamide) (pNIPAM) microgels with silver satellites (AgSTs) incorporated within microgel structure. Spherical AuNPs 50 nm in diameter are initially synthesized and used growing a pNIPAM shell temperature stimulus response. subsequently grown on Au core by diffusing Ag salt through hydrophilic...
We report on the fabrication of a SERS substrate comprising magnetic and silver particles encapsulated within poly(N-isopropylacrylamide) (pNIPAM) thermoresponsive microgel. This colloidal has ability to adsorb analytes from solution while it is expanded (low temperature) reversibly generate hot spots upon collapse (high temperature or drying). Additionally, functionality permits concentration composite into small spatial regions, which can be exploited decrease amount material per analysis...
A versatile water-method for the controlled growth of Ag nanoparticles deposited onto surface SiO<sub>2</sub> spheres is developed. The nanohybrid systems exhibited exceptional SERS and catalytic properties.
In this study, we report on the fabrication of nanoassemblies composed by Au and bimetallic core–shell Au@Ag nanorods immobilized onto pH-responsive poly(2-vinylpyridine) (P2VP) brushes. The general process includes synthesis gold (through seed mediated method) a subsequent reduction AgNO3 surface. These colloidal particles were carboxy-terminated P2VP brushes (COOH-P2VP), previously grafted underlying substrates (silicon wafers glass slides). UV–vis spectroscopy transmission electron...
Microgel grow-bags: Surface-enhanced Raman scattering (SERS)-active bimetallic core–shell spheres can be grown inside poly(N-isopropylacrylamide) (pNIPAM) microgels (see figure). Detailed facts of importance to specialist readers are published as "Supporting Information". Such documents peer-reviewed, but not copy-edited or typeset. They made available submitted by the authors. Please note: The publisher is responsible for content functionality any supporting information supplied Any queries...
We report on the fabrication of thermally responsive hollow pNIPAM particles through oxidation metal core in an Au@pNIPAM system. The selective Au is achieved by addition AuCl4(-) to aqueous dispersion presence cetyltrimethylammonium bromide (CTAB). fabricate with three cross-linking densities (N,N'-methylenebis(acrylamide), BA, at 5%, 10%, and 17.5%). study effect amount BA within microgel network was performed dynamic light scattering (DLS), transmission electron microscopy (TEM), atomic...
Here, temperature-sensitive hybrid poly(N-isopropylacrylamide) (pNIPAM) nanosystems with magnetic response are synthesised and investigated for controlled release of 5-fluorouracil (5FU) oxaliplatin (OXA). Initially, nanoparticles (@Fe3O4) by co-precipitation approach functionalised acrylic acid (AA), 3-butenoic (3BA) or allylamine (AL) as comonomers. The thermo-responsive polymer is grown free radical polymerisation using N-isopropylacrylamide (NIPAM) monomer, N,N'-methylenbisacrylamide...
The design of colloidal nanostructures as surface-enhanced Raman scattering (SERS) substrates requires control over both structural and optical characteristics. A widespread expectation is that the SERS efficiency depends crucially on whether plasmonic excitation matches exciting laser wavelength. However, also balance between radiative (scattering) nonradiative (absorbing) properties plays a major role, regarding near-field enhancement experimentally observed signal intensity. We present...
Ag2S semiconductor nanoparticles (NPs) are near-infrared luminescent probes with outstanding properties (good biocompatibility, optimum spectral operation range, and easy biofunctionalization) that make them ideal for in vivo imaging. NPs have, indeed, made possible amazing challenges including brain imaging advanced diagnosis of the cardiovascular system. Despite continuous redesign synthesis routes, emission quantum yield (QY) is typically below 0.2%. This leads to a low brightness avoids...
Paclitaxel (PTX) is one of the drugs choice in treatment breast and lung cancer. However, its severe side effects, including mielosuppression, cardiotoxicity neurotoxicity, frequently cause to be discontinued. Solid lipid nanoparticles (NPs) glyceril tripalmitate (tripalmitin) loaded with PTX (Tripalm-NPs-PTX) modifications by addition hexa(ethylene glycol), β-cyclodextrin macelignan were developed. All NPs-PTX formulations displayed excellent hemocompatibility significantly enhanced...
In this work, we describe a new methodology for the preparation of monodisperse and thermosensitive microgels with magnetic core. order to produce such material, hydrophobic Fe(3)O(4) nanoparticles were prepared by two methods: thermal decomposition coprecipitation. The surface these was modified addition 3-butenoic acid, after that dispersed in water submitted free radical polymerization at 70 °C presence N-isopropylacrylamide (NIPAM) bisacrylamide. result reaction By varying amount it...
The optimal dopant concentration in UCNPs for simultaneous visible and NIR luminescence was determined by controlling the sensitizer-to-activator ratio while maintaining total amount of dopants.
We have fabricated an implantable dressing material able to reduce antipressure ulcer disease. This biomaterial is based on electrospun poly(lactic acid) (PLA) nanofibers (NFs) containing the hydroethanolic extract (HE) of T. ramosissimum. Optimized synthesis conditions (17-PLA/HE NFs) resulted in homogeneous and nonwoven mat structures formed by polymeric NFs. included a kinetic release assay where chemical main released compounds were identified using nuclear magnetic resonance. The...
Variable Falle: Kolloide aus Goldnanopartikeln mit einer Beschichtung Poly(N-isopropylacrylamid)-Mikrogel (pNIPAM) können Moleküle je nach Temperatur auf verschiedene Art fixieren (siehe Schema). Die poröse pNIPAM-Schale verhindert eine elektromagnetische Kopplung zwischen den Metallpartikeln, sodass bei Messungen der oberflächenverstärkten Raman-Streuung (SERS) hoch reproduzierbare Ergebnisse erhalten werden. Detailed facts of importance to specialist readers are published as "Supporting...
We report a practical method for biofunctionalization of fluoropolymers based on noncovalent, fluorous interactions and click chemistry that allows incorporation biomolecules under physiological solutions. demonstrate the by immobilization an antimicrobial peptide (AMP) thin films fluorosilicone contact lens. The surfaces were dip-coated with fluorous-tagged oligo(ethylene) chain terminated reactive group, such as alkynyl group. This simple step generates "clickable" surface. noncovalent...