A5067666378- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Meningioma and schwannoma management
- Glioma Diagnosis and Treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Neurosurgical Procedures and Complications
- Head and Neck Surgical Oncology
- Pituitary Gland Disorders and Treatments
- Adrenal and Paraganglionic Tumors
- Cerebral Venous Sinus Thrombosis
- Cerebrospinal fluid and hydrocephalus
- Spinal Fractures and Fixation Techniques
- Neurofibromatosis and Schwannoma Cases
- Trigeminal Neuralgia and Treatments
- Acute Ischemic Stroke Management
- Bone Tumor Diagnosis and Treatments
- Cardiovascular Health and Disease Prevention
- Multiple Myeloma Research and Treatments
- Sarcoma Diagnosis and Treatment
- Oral and Maxillofacial Pathology
- Facial Nerve Paralysis Treatment and Research
- Pelvic and Acetabular Injuries
- Peripheral Nerve Disorders
Mayo Clinic
2017-2025
Mayo Clinic in Arizona
2020-2024
Boston Children's Hospital
2024
Harvard University
2024
Neurological Surgery
2019-2023
WinnMed
2020-2022
Milliman (United States)
2022
Mayo Clinic in Florida
2020
University of Colorado Anschutz Medical Campus
2016-2017
University of Colorado Denver
2016-2017
Glioblastoma multiforme (GBM) is a devastating tumour with abysmal prognoses. We desperately need novel approaches to understand GBM biology and therapeutic vulnerabilities. Extracellular vesicles (EVs) are membrane-enclosed nanospheres released locally systemically by all cells, including tumours, tremendous potential for intercellular communication. Tumour EVs manipulate their local environments as well distal targets; may be mechanism tumourigenesis in the recurrent setting. hypothesized...
Introduction: Iatrogenic cervical artery dissection (CeAD) may result from various procedures such as procedural and diagnostic angiography. Due to the rarity of iatrogenic CeAD, existing literature on management outcomes is limited. This observational cohort study investigates clinical approaches long-term CeAD after endovascular interventions. Methods: We conducted a retrospective chart review analyze patients who underwent treatments at Mayo Clinic 1998 2021. focused with resulting...
OBJECTIVE Prophylactic use of antiepileptic drugs (AEDs) in seizure-naïve brain tumor patients remains a topic debate. This study aimed to characterize subset at highest risk for new-onset perioperative seizures (i.e., intraoperative and postoperative occurring within 30 days surgery) who may benefit from prophylactic AEDs. METHODS The authors conducted retrospective case-control all adults had undergone resection or biopsy the authors' institution between January 1, 2004, June 31, 2015. All...
OBJECTIVE Opportunistic Hounsfield unit (HU) determination from CT imaging has been increasingly used to estimate bone mineral density (BMD) in conjunction with assessments dual energy x-ray absorptiometry (DXA). The authors sought compare the effect of teriparatide on HUs across different regions pelvis, sacrum, and lumbar spine, as a surrogate measure for effects lumbosacropelvic instrumentation. METHODS A single-institution retrospective review patients who had treated at least 6 months...
Cerebrospinal fluid–venous fistula is an increasingly recognized cause of spontaneous intracranial hypotension.1 The site the leak between dural sleeve around a spinal nerve root and surrounding foraminal veins. In appropriately investigated patients, transvenous embolization draining paraspinal veins has been shown to be effective way treating disease, with low periprocedural morbidity, improvement in symptoms radiological appearances.2 Video 1 shows technique employed typical case using...
To define the in-hospital course, complications, short- and long-term functional outcomes of patients with angiographically negative subarachnoid hemorrhage (anSAH), particularly those aneurysmal-pattern anSAH (aanSAH).Retrospective cohort study aneurysmal (aSAH), aanSAH, perimesencephalic-pattern (panSAH) treated at a single tertiary referral center between January 2006 April 2018. Ninety-nine (33 aanSAH 66 panSAH) 464 aSAH were included in this study. Outcomes symptomatic hydrocephalus...
Pelvic incidence (PI) is a commonly utilized spinopelvic parameter in the evaluation and treatment of patients with spinal deformity believed to be fixed parameter. However, PI assumes that there no motion across sacroiliac (SI) joint, which has been disputed recent literature. The objective this study was determine if SI joint vacuum sign have change between supine standing positions.
Background Iatrogenic cervical artery dissection (CeAD) results from various procedures including interventional angiographic and diagnostic angiography. CeAD is rare, resulting in limited literature on management outcomes. This observational cohort study investigates approaches outcomes of iatrogenic after endovascular interventions. Methods We conducted a retrospective review for patients who underwent intervention with at Mayo Clinic, Rochester, MN, 1998 to 2021. Pertinent patient factors...
Postoperative pain can limit the recovery of children undergoing craniotomy for tumor resection, and management is highly variable between institutions practitioners. Nonsteroidal antiinflammatory drugs (NSAIDs) are effective in treating postoperative following craniotomy, but their use has been limited by concerns about hemorrhage. The risk hemorrhage not insignificant patients resection. No study specifically addressed safety NSAIDs immediate setting resection pediatric patients.
OBJECTIVE Placement of a cerebrospinal fluid diversion device (i.e., shunt) is routine pediatric neurosurgical procedure, often performed in the first weeks life for treatment congenital hydrocephalus. In postoperative period, shunt placement may be complicated by subdural, catheter tract, parenchymal, and intraventricular hemorrhages. The authors observed subset infants neonates who developed multifocal intraparenchymal hemorrhages (MIPH) following sought to determine any predisposing...