A5113793407- Radiation Detection and Scintillator Technologies
- Medical Imaging Techniques and Applications
- Nuclear Physics and Applications
- Atomic and Subatomic Physics Research
- Advanced X-ray and CT Imaging
- Laser-Plasma Interactions and Diagnostics
- Laser-induced spectroscopy and plasma
- Laser-Matter Interactions and Applications
- Advanced MRI Techniques and Applications
- Radiation Dose and Imaging
- Advanced X-ray Imaging Techniques
- Digital Radiography and Breast Imaging
- High-pressure geophysics and materials
- Digital Communication and Language
- Thermography and Photoacoustic Techniques
- Advanced Thermodynamic Systems and Engines
- Magnetic Properties of Alloys
- Environmental and Ecological Studies
- Laser Material Processing Techniques
- Water Resource Management and Quality
- Historical Art and Architecture Studies
- Neuroblastoma Research and Treatments
- MRI in cancer diagnosis
- Advanced Optical Sensing Technologies
- Glioma Diagnosis and Treatment
Instituto Nacional de Neurología y Neurocirugía
2025
Centro de Estudios Superiores Universitarios
2024
Universitat Politècnica de València
2013-2017
Instituto de Instrumentación para Imagen Molecular
2012-2017
Consejo Superior de Investigaciones Científicas
2013
Centro Nacional de Aceleradores
2013
Instituto Politécnico Nacional
2011
Ludlum Measurements (United States)
2006-2007
University of Notre Dame
2007
Altamira Technologies
2006
The authors have developed a trimodal PET∕SPECT∕CT scanner for small animal imaging. gamma ray subsystems are based on monolithic crystals coupled to multianode photomultiplier tubes (MA-PMTs), while computed tomography (CT) comprises commercially available microfocus x-ray tube and CsI scintillator 2D pixelated flat panel detector. In this study the will report design performance evaluation of multimodal system.X-ray transmission measurements performed cone-beam geometry. Individual...
Background Oligodendrogliomas are a distinct subtype of gliomas frequently characterized by the 1p/19q codeletion and isocitrate dehydrogenase (IDH) gene mutations, both associated with improved therapeutic response prolonged survival. These genetic alterations modulate transsulfuration pathway, leading to increased methionine uptake tumor cells. Positron emission tomography (PET) 11C-labeled (MET PET) leverages these metabolic changes, providing noninvasive means distinguish...
In Positron Emission Tomography (PET) detectors based on monolithic scintillators, the photon interaction position needs to be estimated from light distribution (LD) photodetector pixels. Due finite size of scintillator volume, symmetry LD is truncated everywhere except for crystal center. This effect produces a poor estimation positions towards edges, an especially critical situation when linear algorithms, such as Center Gravity (CoG), are used. When all faces painted black, one in contact...
We present the calibration and performance tests carried out with two detectors for intense proton pulses accelerated by lasers. Most of procedures were realized beams 0.46-5.60 MeV from a tandem accelerator. One approach made use radiochromic films, which we calibrated relation between optical density energy deposition over more than three orders magnitude. The validity these results our analysis algorithms has been confirmed controlled irradiation film stacks reconstruction total beam...
In this paper, the capabilities of a wide-area gamma ray photosensor based on SiPM array are investigated. For purpose, we have mounted an 144 <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex Notation="TeX">$(12\times12)$</tex></formula> SiPMs with individual active area Notation="TeX">$3 \times 3~\hbox{mm}^{2}$</tex></formula> and pitch Notation="TeX">$4.2~\hbox{mm}$</tex></formula> , thus covering...
Silicon photomultipliers (SiPMs) have become an alternative to traditional tubes due several features. However, their implementation form large arrays is still a challenge especially relatively high intrinsic noise, depending on the chosen readout. In this contribution, two modules composed of 12 ×12 SiPMs with area roughly 50 mm×50 mm are used in coincidence. Coincidence resolving time (CRT) results field-programmable gate array, combination digital converter, shown as function both sensor...
In this work we show pilot tests of PET detector blocks using the TOF-PET ASIC, coupled to SiPM arrays and different crystal configurations. We have characterized main ASIC features running calibration processes compensate time dispersion among ASIC/SiPM paths as well for walk on arrival optical photons. The aim is use LYSO monolithic crystals explore their photon Depth Interaction (DOI) capabilities, keeping good energy spatial resolutions. First been carried out with arrays. Here made it...
We report on benchmark tests of a 3 TW/50 fs, table-top laser system specifically developed for proton acceleration with an intrinsic pump rate up to 100 Hz. In two series single-shot measurements differing in pulse energy and contrast the successful operation diode pumped is demonstrated. Protons have been accelerated 1.6 MeV interactions pulses focused aluminium mylar foils between 0.8 25 μm thickness. Their spectral distributions maximum energies are consistent former experiments under...
The splitting of the field view (FOV) in polar voxels is proposed this work order to obtain an efficient description a cone-beam computed tomography (CT) scanner. symmetric-polar pixelation makes it possible deal with 3D iterative reconstruction considering number projections and voxel sizes typical CT preclinical imaging.
We present the first results of an MR compatible PET system based on continuous crystals and SiPM detectors, along with a dedicated application-specific integrated circuit (ASIC) for readout stage. The use scintillation preserves spatial distribution light each γ--ray impact, which can be reconstructed small number statistical moments Therefore, it is possible to reduce analogue-to-digital conversion channels. current ASIC measure up 8 distribution, providing information about X Y photon...
In γ-ray detectors, monolithic scintillation crystals offer the possibility of preserving light distribution especially when painted black. The statistical moments this provide accurate information on three photon impact coordinates, including their depth interaction (DOI). Digital SiPMs (dSiPMs) return digital based pixels about collected distribution, since signal is a sum trigger bins. work we present, for first time, an analysis using black and state-of-the-art dSiPMs. Two 32.6 ×32.6 mm...
MAMMI is a dedicated breast positron emission tomograph (PET) based on monolythic LYSO crystals, with transaxial field of view (FOV) 170 mm. It has been upgraded by adding second ring detectors that extends the axial FOV from 40 mm to 94.4 mm, in order improve its sensitivity and reduce acquisition time. In this work we present performance evaluation dual PET discussion about contribution addition detectors, compensation detector blur increase scintillator thickness. Experimental...
The radiation sensitive part of the wide-field, small gamma camera Sentinella™ 108 consists a monolithic, 102 × mm2 wide CsI(Na) crystal coupled to four position-sensitive photomultipliers. These are read out via resistor mesh reducing 256 PMT channels digitized values which allow for an image reconstruction, based on polynomials, with high spatial resolution. sensor areas between neighboring PMTs suffer from reduced detection efficiency scintillation light. corresponding lack signal...
Developing front-end electronics to improve charge detection and time resolution in gamma-ray detectors is one of the main tasks performance new multimodal imaging systems that merge information Magnetic Resonance Imaging Gamma Camera or PET tomographs.
Monolithic scintillation crystals offer the possibility to preserve light distribution, specially when black painted. Furthermore, statistical moments of that distribution can provide accurate information about three spatial components. Nevertheless, for monolithic crystal estimation has an associated error due symmetry truncation towards borders. For 2-D impact coordinates determination, this is called compression as it accentuated near edges. The computation all centered is, therefore,...
In this contribution, Coincidence Resolving Time (CRT) results with the developed multichannel FPGA-TDC are showed as a function of different configurations for both, sensor bias voltage and digitizer threshold. The dependence CRT matrix temperature, amount SiPM active area crystal type also analyzed. Preliminary measurements carried out array 2 mm pixel size 10 height have shown time resolutions entire 144 two-detectors ensemble good 800 ps.
La sobreutilización de las redes sociales como medio interaccionar con otras personas durante el COVID-19 podría tener consecuencias negativas para la salud mental en determinados estilos afrontamiento. El objetivo presente investigación fue analizar relación entre afrontamiento, frecuencia uso y los niveles ansiedad depresión adultos jóvenes COVID-19. Se realizó un experimento que participaron 643 sujetos completaron unos cuestionarios afrontamiento (Cuestionario Afrontamiento del Estrés;...
A histological intraoperative analysis of tissue specimen is usually required for evaluation sentinel lymph node (SLN) and determination margins surgical resection. Currently, this performed by Touch Imprint Cytology (TIC), Frozen Section (FS) analysis, scrape cytology or a combination these methods. We propose an alternative approach based on Magnetic Resonance Imaging (MRI). In particular, in contribution we present the development, components, characterization as well first images...
In this work, a direct image reconstruction algorithm for PET is proposed. This method follows naturally from the concept of LOR, and easily admits depth interaction time flight information. addition, does not require computation sinograms or system matrix. Thus, it restricted in formation high pixel density images allows real-time (simultaneously to data acquisition process). One key advantages preservation frequencies, producing accurate that can be generated resolution, because lack space...