A5101405183- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- MicroRNA in disease regulation
- Catalysts for Methane Reforming
- Catalytic Processes in Materials Science
- Catalysis and Hydrodesulfurization Studies
- Thermochemical Biomass Conversion Processes
- Gut microbiota and health
- Viral-associated cancers and disorders
- RNA Research and Splicing
- Circular RNAs in diseases
- RNA Interference and Gene Delivery
- Caveolin-1 and cellular processes
- Craniofacial Disorders and Treatments
- Bacteriophages and microbial interactions
- Barrier Structure and Function Studies
- Glycosylation and Glycoproteins Research
- Electrocatalysts for Energy Conversion
- Dysphagia Assessment and Management
- Cancer Mechanisms and Therapy
- Eicosanoids and Hypertension Pharmacology
- Virus-based gene therapy research
- Cleft Lip and Palate Research
- Kruppel-like factors research
- Diet and metabolism studies
Nanchang University
2018-2024
University of Chinese Academy of Sciences
2021-2024
Second Affiliated Hospital of Nanchang University
2018-2024
Institute of Process Engineering
2024
Jishou University
2022-2023
Southeast University
2020-2021
Wuhan Institute of Virology
2021
Chinese Academy of Sciences
2021
Central South University
2014-2019
Hunan Cancer Hospital
2015-2019
MiR-140-5p is low expression and acts as a tumor suppressor in various types of human cancers. However, the potential role miR-140-5p retinoblastoma (RB) remains unknown. In present study, we performed miRNA microarray analysis to investigate whether miRNAs are associated with RB tumorigenesis tissues. We found that large set were ectopic expressions most significantly down-regulated tissues compared normal retinas. addition, clinicopathological features (differentiation, invasion, T...
Altered microRNA (miRNA) associated with gastric cancer (GC) development and miR-17 miR-106b were differentially expressed in GC tissues. This study detected serum levels of expression GC, benign disease (BGD) healthy controls to assess them as tumor markers for GC. Serum samples from 40 32 BGD (10 ulcer, 14 polyps, 8 ulcer polyps) 36 individuals subjected quantitative reverse transcription polymerase chain reaction (qRT-PCR) analysis expression. The data showed that the significantly...
The flotillin (Flot) protein family has been demonstrated to be involved in the development and progression of various cancers. However, role Flot2 gastric carcinomas remains unknown. present study aimed investigate clinical significance carcinomas. Data tissue microarray including 90 cases carcinoma samples their matched adjacent tissues showed that, among tissues, 65 no expression, 25 low expression Flot2, its positive rate was only 38.5% (25/90); however, carcinomas, 6 26 28 moderate 30...
As one of the most common primary intraocular carcinomas, retinoblastoma generally stems from inactivation RB1 gene in retinal cells. Antisense non-coding RNA INK4 locus (ANRIL), a long (lncRNA), has been reported to affect tumorigenesis and progression various cancers, including gastric cancer non-small cell lung cancer. However, limited investigations emphasized role ANRIL human retinoblastoma. Hence, current study was intended investigate effects on proliferation, apoptosis, invasion...
Nasopharyngeal carcinoma (NPC) is an endemic tumor with a relatively high incidence in Southern China and Southeast Asia. Paclitaxel combination chemotherapy has been used for treatment of advanced NPC. However, failure often occurs due to development acquired paclitaxel resistance. In this study, we first established paclitaxel-resistant CNE-1/Taxol, HNE-2/Taxol 5–8F/Taxol cell sublines by treating the parental CNE-1, HNE-2 5–8F cells increasing doses about 5 months, respectively. Then,...
Involved in diverse biological processes, bacterial sRNAs are novel regulators of gene expression involved a wide array processes. To identify Brucella abortus, we performed genome-wide computational prediction with integrated SIPHT and NAPP results. In total, 129 sRNA candidates were identified, which 112 sRNA. Twenty tested by RT-PCR seven could be verified. The putative targets these also predicted This study provides significant resource for the future sRNAs, as well how influence B....
Abstract Long non-coding RNAs (lncRNAs) have been reported to be dysregulated and play a crucial role in the progression of cancer. LncRNA DANCR has recently revealed involved tumorigenesis numerous types cancer, including osteosarcoma, gastric breast hepatocellular carcinoma, colorectal However, expression profiles biological relevance papillary thyroid cancer (PTC) not yet reported. In present study, level PTC tissues adjacent normal was detected by reverse transcription-quantitative PCR...
Background Mounting evidence has demonstrated the associations between gut microbiota, microbiota-derived metabolites, and cerebrovascular diseases (CVDs). The major categories of CVD are ischemic stroke (IS), intracerebral hemorrhage (ICH), subarachnoid (SAH). However, causal relationship is still unclear. Methods A two-sample Mendelian randomization (MR) study was conducted leveraging summary data from genome-wide association studies. inverse variance-weighted, maximum likelihood, weighted...
Aim: To investigate the clinical roles of LINC00152 and SNHG12 in papillary thyroid carcinoma (PTC). Methods:LINC00152 expression was sought analysis gene omnibus, The Cancer Genome Atlas GEPIA datasets. Tumor adjacent normal tissues were collected from 97 PTC 44 benign nodules patients. evaluated by quantitative real-time polymerase chain reaction. association between level clinicopathologic characteristics analyzed χ2 test. Receiver operating characteristic curves plotted to evaluate...
China has had explosive growth in ischemic stroke (IS) burden with significant ethnic and geographic disparities. The aim of this study was to explore the possible combination effect between gut microbiota traditional potentially modifiable risk factors for IS among two minorities (Tujia Miao) Han population. Herein, we first used 16 S rRNA sequencing compare microbial compositions 82 patients first-ever vs. normal controls (NCs) Han, Tujia, Miao people 1 May 2018 30 April 2019, from Xiangxi...
Objective To investigate the role of Luxs gene on regulation virulence factors in Salmonella typhimuriumn.Methods knock-out strain typhimurium line 14028S was constructed.Media with or wild type bacteria were added into media cultured human intestinal epithelial cells Caco.The numbers colony formation unit(cfu)were calculated so as to compare invasion abihty.Northern blotting performed examine expression.Results When early logarithmic phase cfu number 590,and middle and late logarithmic,and...