A5052645254- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- Electrochemical sensors and biosensors
- Electrochemical Analysis and Applications
- Malaria Research and Control
- MicroRNA in disease regulation
- Bacteriophages and microbial interactions
- Molecular Biology Techniques and Applications
- Reproductive Biology and Fertility
- Ovarian function and disorders
- RNA Interference and Gene Delivery
- Viral Infections and Immunology Research
- Hepatitis B Virus Studies
- Cancer-related Molecular Pathways
- Plant nutrient uptake and metabolism
- Pulmonary Hypertension Research and Treatments
- Liver Disease Diagnosis and Treatment
- Cardiovascular Function and Risk Factors
- Advanced Biosensing Techniques and Applications
- Estrogen and related hormone effects
- Plant Micronutrient Interactions and Effects
- Menopause: Health Impacts and Treatments
- Retinopathy of Prematurity Studies
- Microfluidic and Capillary Electrophoresis Applications
- SARS-CoV-2 detection and testing
Southwest University
2020-2025
Hebei University
2025
Yunnan Institute of Parasitic Diseases
2010-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2015-2024
Peking Union Medical College Hospital
2015-2024
Hunan University of Technology
2015-2024
Guangxi Medical University
2013-2024
Guangzhou Education Bureau
2024
Second Affiliated Hospital of Nanchang University
2013-2024
Nanchang University
2013-2024
Exosomes are membrane nanovesicles carrying molecular information that may reflect the biological and genetic characteristics of their parent cells.
Abstract Inflammation triggers pulmonary vascular remodelling. Ferroptosis, a nonapoptotic form of cell death that is triggered by iron-dependent lipid peroxidation and contributes to the pathogenesis several inflammation-related diseases, but its role in hypertension (PH) has not been studied. We examined endothelial ferroptosis PH potential mechanisms. Pulmonary artery cells (PAECs) lung tissues from monocrotaline (MCT)-induced rats were analysed for markers, including peroxidation, labile...
Aptamers are short single-stranded DNA or RNA oligonucleotides and can be selected from synthetic combinatorial libraries in vitro. They have a high binding affinity specificity for their targets. Agarose gels, nitrocellulose membranes, adsorptive microplates often used as carriers to immobilize targets the SELEX (systematic evolution of ligands by exponential enrichment) process, but subsequent separation step is tedious time-consuming. Therefore, we magnetic nanoparticles (MNPs) target,...
Although gold nanorods (GNRs) have been prepared with a wide range of methods for their uses as novel diagnostic and therapeutic agents, the synthesis monodispersed GNRs high yields size tunability still requires further improvements. We report on simple one-pot method preparing highly using phenols (e.g., hydroquinone, 1,2,3-trihydroxybenzene, 1,2,4-trihydroxybenzene) reducing agent NaBH4 initiating reactant. Fine-tuning LSPR peak position phenols-reduced from 550 to 1150 nm is accomplished...
Exosomes have been recognized as promising sources of biomarkers for early cancer diagnosis due to their important role in the occurrence and metastasis cancer, so development a sensitive low-cost detection method exosomes is highly desirable. In this paper, we report fluorescence competitive based on an aptamer specific CD63 (an exosome transmembrane protein). Aptamer-modified magnetic beads were hybridized with Cy3-labeled short sequence complementary region aptamer. presence exosomes,...
Abstract Increasing grain zinc (Zn) concentration of cereals for minimizing Zn malnutrition in two billion people represents an important global humanitarian challenge. Grain field-grown wheat at the scale ranges from 20.4 to 30.5 mg kg −1 , showing a solid gap biofortification target human health (40 ). Through group field experiments, we found that low was not closely linked historical replacements varieties during Green Revolution, but greatly aggravated by phosphorus (P) overuse or...
The adaptations of root morphology, physiology, and biochemistry to phosphorus supply have been characterized intensively. However, characterizing these at molecular level is largely neglected under field conditions. Here, two consecutive experiments were carried out investigate the agronomic traits wheat (Triticum aestivum L.) six P-fertilizer rates. Root samples collected flowering dry weight, length density, arbusular-mycorrhizal colonization rate, acid phosphatase activity in rhizosphere...
Interleukin (IL)-18 gene polymorphisms have been found to play multiple roles in various diseases. However, studies focused on its involvement hepatocellular carcinoma (HCC) remains controversial, and no much study has taken IL-18 serum levels into consideration. This investigates the association between risk of hepatitis B virus-related HCC their impact levels. A total 153 patients 165 healthy controls were enrolled this study. Polymorphisms at positions −607C/A −137G/C determined using...
A mercury ion aptamer electrochemical biosensor based on a Thymine-Hg2+-Thymine (T-Hg2+-T) structure has been constructed and successfully used to detect ions in tap water samples. The was assembled using aptamer-functionalized AuNPs-modified glass carbon electrode (aptamer/(AuNPs/CS)₂/GCE) capable of specifically detecting through T-Hg2+-T structure. experimental results indicated the optimum performance prepared when (AuNPs/CS)₂/GCE surface modified with 1.0 μM incubated Hg2+ for 60 min....