David J. S. Birch

ORCID: 0000-0001-6400-1270
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About
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Research Areas
  • Analytical Chemistry and Sensors
  • Advanced Fluorescence Microscopy Techniques
  • Photochemistry and Electron Transfer Studies
  • Protein Interaction Studies and Fluorescence Analysis
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Spectroscopy and Quantum Chemical Studies
  • Advanced biosensing and bioanalysis techniques
  • Nanocluster Synthesis and Applications
  • Thermography and Photoacoustic Techniques
  • Optical Imaging and Spectroscopy Techniques
  • Advanced Optical Sensing Technologies
  • Photoreceptor and optogenetics research
  • Chemical Synthesis and Analysis
  • Electrochemical Analysis and Applications
  • Lipid Membrane Structure and Behavior
  • Molecular Sensors and Ion Detection
  • Electrochemical sensors and biosensors
  • melanin and skin pigmentation
  • Alzheimer's disease research and treatments
  • Surfactants and Colloidal Systems
  • Nanoplatforms for cancer theranostics
  • Spectroscopy and Laser Applications
  • Lanthanide and Transition Metal Complexes
  • Analytical Chemistry and Chromatography
  • Spectroscopy Techniques in Biomedical and Chemical Research

University of Strathclyde
2015-2024

Scottish Universities Physics Alliance
2014-2024

Horiba (United Kingdom)
2004-2020

Direction des énergies
2003

Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2003

Centre National de la Recherche Scientifique
2003

University of Manchester
1977-2003

Total (United Kingdom)
2003

The Open University
1991-2003

Bangor University
2003

A <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$192 \times 128$ </tex-math></inline-formula> pixel single photon avalanche diode (SPAD) time-resolved counting (TCSPC) image sensor is implemented in STMicroelectronics 40-nm CMOS technology. The 13% fill factor, notation="LaTeX">$18.4\,\,\mu \text {m} 9.2\,\,\mu \text{m}$ contains a 33-ps resolution, 135-ns full scale, 12-bit time-to-digital converter...

10.1109/jssc.2019.2905163 article EN IEEE Journal of Solid-State Circuits 2019-04-03

Abstract The oxygen evolution reaction (OER) is of great importance for renewable energy conversion and storage; however, the intrinsic process sluggish suffers from severe efficiency loss as well large overpotentials. In this work, with introduction plasmonic effects by design Au‐MnO 2 hybrid catalysts, it demonstrated that photophysical phenomenon could largely promote confinement outer electrons Mn cations “hot holes” generated on gold surface. These work effective electron trapper to...

10.1002/adfm.201801573 article EN Advanced Functional Materials 2018-06-06

With the fast development of new science and technology, wearable devices are in great demand modern human daily life. However, energy problem is a long-lasting issue to achieve real smart, wearable, portable devices. Flexible thermoelectric generators (TEGs) based on conversion systems can convert body waste heat into electricity with excellent flexibility wearability, which shows direction solving this issue. Here work, polyethylenimine (PEI) gold nanoparticles (Au NPs) twin...

10.1021/acsami.4c00981 article EN ACS Applied Materials & Interfaces 2024-03-30

Reports the development of a new technique-optothermal transient emission radiometry (OTTER)-for studying optical absorption, thermal diffusivities and associated properties in opaque materials. In essence, technique makes use information content observed by means wideband infrared detector, following pulsed excitation material. Some preliminary observations, including study several commercial pigments are presented.

10.1088/0022-3735/17/6/020 article EN Journal of Physics E Scientific Instruments 1984-06-01

We have developed a coaxial thyratron-gated flashlamp capable of being operated with high stability over much wider range conditions than previous flashlamps. Novel methods for continuously monitoring discharge are described. present comprehensive data on the dependence pulse width and intensity operating parameters. Using single photon detection technique an overall instrumental profile 950 ps FWHM 630 rise time has been obtained using hydrogen as filler gas. An 1.2 ns can be routinely in...

10.1063/1.1136742 article EN Review of Scientific Instruments 1981-08-01

Alternative, non-electrochemistry-based technologies for continuous glucose monitoring are needed eventual use in diabetes mellitus. As part of a programme investigating fluorescent sensors, we have developed fibre-optic biosensors using glucose/galactose binding protein (GBP) labelled with the environmentally sensitive fluorophore, Badan. GBP-Badan was attached via an oligohistidine-tag to surface Ni-nitrilotriacetic acid (NTA)-functionalized agarose or polystyrene beads. Fluorescence...

10.1039/c0an00430h article EN The Analyst 2010-12-17

Two-photon luminescence (TPL) from gold nanorods shows considerable potential in biological imaging. We study the imaging of Madin-Darby canine kidney (MDCK) cells using fluorescence lifetime microscopy (FLIM). FLIM provides images with better contrast and sensitivity than intensity The characteristic is found to be less 100 ps, which can used distinguish other fluorescent labels endogenous fluorophores

10.1117/1.3366646 article EN Journal of Biomedical Optics 2010-01-01

Fluorescent gold nanoclusters encapsulated by proteins have attracted considerable attention in recent years for their unique properties as new fluorescence probes biological sensing and imaging.

10.1039/c5cp02380g article EN Physical Chemistry Chemical Physics 2015-01-01

We demonstrate measurement of the intrinsic fluorescence decay a protein excited with new and inexpensive optical source based on light emitting diode (LED) giving 600 ps pulses at ∼280 nm. believe this will offer significant capabilities for research development.

10.1088/0957-0233/15/11/l02 article EN Measurement Science and Technology 2004-10-12

A competing 1,3-rearrangement of allyl stannanes has been demonstrated to occur under the normal thermal homolytic transfer reaction conditions which limits substitution patterns in these processes; two methacrylyl are described allow moiety alkyl bromides and iodides mild conditions.

10.1039/c39860001339 article EN Journal of the Chemical Society Chemical Communications 1986-01-01

We report the effects of quercetin, a flavonoid present in human diet, on early stage beta-amyloid (Aβ) aggregation, seminal event Alzheimer's disease. Molecular level changes Aβ arrangements are monitored by time-resolved emission spectral (TRES) measurements fluorescence Aβ's single tyrosine intrinsic fluorophore (Tyr). The results suggest that quercetin binds β-amyloid oligomers at stages their which leads to formation modified and hinders creation β-sheet structures, potentially preventing onset

10.1021/acs.jpcb.2c02763 article EN cc-by The Journal of Physical Chemistry B 2022-09-19

We review the principle of operation, performance and application different types single-photon timing detectors presently employed in fluorescence lifetime determination using time-correlated counting technique. The devices discussed include side-on linear focused photomultiplier tubes, microchannel plate photomultipliers avalanche photodiodes.

10.1088/0957-0233/7/2/002 article EN Measurement Science and Technology 1996-02-01

Abstract. Fluorescence of synthetic melanin in dimethyl sulfoxide has been excited by two‐photon absorption at 800 run, using 120 fs pulses with photon flux densities 10 27 cm 2 s 1 . The shortest main component the three‐exponential decay fluorescence is 200 ± ps. overall spectral shape red‐shifted respect to 400 nm fluorescence. Two‐photon also measured from excised samples healthy human skin tissue. Because selectivity excitation via resonant absorption, it hypothesized that this way may...

10.1111/j.1751-1097.1999.tb07982.x article EN Photochemistry and Photobiology 1999-08-01

Human serum albumin (HSA) complexation with quercetin, a flavonoid commonly present in human diet, was monitored by means of fluorescence decays the single HSA tryptophan - Trp214. Data analysis based on fitting to multiexponential functions and determining lifetime distributions revealed high sensitivity binding quercetin. Results are discussed terms rotamer model for tryptophan, HSA-quercetin potential quercetin energy transfer. Evidence stabilising rotamers is presented.

10.1117/1.2747623 article EN Journal of Biomedical Optics 2007-01-01
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