A5013057193- Single-cell and spatial transcriptomics
- Genomics and Phylogenetic Studies
- COVID-19 epidemiological studies
- Viral Infections and Outbreaks Research
- Plant Molecular Biology Research
- SARS-CoV-2 and COVID-19 Research
- Plant Virus Research Studies
- Insect Resistance and Genetics
- Cell Image Analysis Techniques
- Insect-Plant Interactions and Control
Nanjing University
2020-2024
Sun Yat-sen University
2021
Pharmaceutical Biotechnology (Czechia)
2020
State Key Laboratory of Pharmaceutical Biotechnology
2020
Single-cell transcriptomics has been fully embraced in plant biological research and is revolutionizing our understanding of growth, development, responses to external stimuli. However, single-cell transcriptomic data analysis plants not trivial, given that there currently no end-to-end solution integration various bioinformatics tools involves a large number required dependencies. Here, we present scPlant, versatile framework for exploring atlases with minimum input provided by users. The...
Rice is a main food crop for more than half of the global population. The brown planthopper (BPH, Nilaparvata lugens) one most destructive insect pests rice. Currently, repeated overuse chemical insecticides represents common practice in agriculture BPH control, which can induce tolerance and provoke environmental concerns. This situation calls innovative widely applicable strategies rice protection against BPH. Here we report that osa-miR162a mediate cross-kingdom RNA interference (RNAi) by...
Plant morphogenesis relies on precise gene expression programs at the proper time and position which is orchestrated by transcription factors (TFs) in intricate regulatory networks a cell-type specific manner. Here we introduced comprehensive single-cell transcriptomic atlas of Arabidopsis seedlings. This result meticulous integration 63 previously published scRNA-seq datasets, addressing batch effects conserving biological variance. spans broad spectrum tissues, including both below-...
Abstract The novel coronavirus disease 2019 (COVID-19) epidemic, which was first identified in Wuhan, China December 2019, has rapidly spread all over and across the world. By end of February 2020, epidemic outside Hubei province been well controlled, yet next wave transmission other countries may have just begun. A retrospective modeling dynamics would provide insights into epidemiological characteristics evaluation effectiveness strict measures that taken by central local governments...
The novel coronavirus disease 2019 (COVID-19) epidemic, which was first identified in Wuhan, China December 2019, has rapidly spread all over and across the world. By end of February 2020, epidemic outside Hubei province been well controlled, yet next wave transmission other countries may have just begun. A retrospective modeling dynamics would provide insights into epidemiological characteristics evaluation effectiveness strict measures that taken by central local governments China. Using a...
Abstract Plant morphogenesis relies on precise gene expression programs at the proper time and position which is orchestrated by transcription factors (TFs) in intricate regulatory networks a cell-type specific manner. Here we presented reference single-cell transcriptomic atlas of Arabidopsis seedlings integration 40 published scRNA-seq datasets from representative tissues as well entire under- above-ground parts. We identified 34 distinct cell types or states, largely expanding our current...