Zhaohui He

ORCID: 0000-0002-8976-9494
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About
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Research Areas
  • Kidney Stones and Urolithiasis Treatments
  • Pediatric Urology and Nephrology Studies
  • Renal and Vascular Pathologies
  • Dialysis and Renal Disease Management
  • Gallbladder and Bile Duct Disorders
  • Genomics and Phylogenetic Studies
  • Single-cell and spatial transcriptomics
  • Gene expression and cancer classification
  • Genomics and Chromatin Dynamics
  • Cell Image Analysis Techniques
  • Gout, Hyperuricemia, Uric Acid
  • Ureteral procedures and complications
  • Galectins and Cancer Biology
  • Organ Donation and Transplantation
  • Phytoplasmas and Hemiptera pathogens
  • Blood Coagulation and Thrombosis Mechanisms
  • Intellectual Property and Patents
  • Gestational Diabetes Research and Management
  • Biotechnology and Related Fields
  • Science, Research, and Medicine
  • Acute Ischemic Stroke Management
  • Genetic Mapping and Diversity in Plants and Animals
  • Metabolism and Genetic Disorders
  • Advanced battery technologies research
  • Urinary Tract Infections Management

The Affiliated Yongchuan Hospital of Chongqing Medical University
2023

Chongqing Medical University
2023

Nanjing University
2022-2023

Nanjing Institute of Technology
2022

Weatherford College
2022

First Affiliated Hospital of Henan University
2022

Affiliated Hospital of Southwest Medical University
2021

Southwest Medical University
2021

Sun Yat-sen University
2007-2019

Eighth Affiliated Hospital of Sun Yat-sen University
2019

Abstract Recent advancements in single-cell RNA sequencing (scRNA-seq) technology have enabled the comprehensive profiling of gene expression patterns at level, offering unprecedented insights into cellular diversity and heterogeneity within plant tissues. In this study, we present a systematic approach to construct database, scPlantDB, which is publicly available https://biobigdata.nju.edu.cn/scplantdb. We integrated transcriptomic profiles from 67 high-quality datasets across 17 species,...

10.1093/nar/gkad706 article EN cc-by-nc Nucleic Acids Research 2023-08-28

To compare the safety and efficacy of fluoroscopic guidance (FG), total ultrasonographic (USG), combined (CG) for percutaneous renal access in mini-percutaneous nephrolithotomy (mini-PCNL).The present study was conducted between July 2014 May 2015 as a prospective randomised trial at First Affiliated Hospital Guangzhou Medical University. In all, 450 consecutive patients with stones >2 cm were to undergo FG, USG, or CG mini-PCNL (150 each group). The primary endpoints stone-free rate (SFR)...

10.1111/bju.13703 article EN BJU International 2016-11-08

Background and Purpose: Percutaneous nephrolithotomy (PCNL) using a small tract is controversial, its indication considered limited. In our center, however, we have performed Chinese minimally invasive PCNL regularly for managing upper-tract calculi. We report experience. Patients Methods: Our technique not just about smaller instruments tracts. overall approach different from the standard PCNL. preferred middle caliceal puncture via 11th rib space also relied mainly on strong irrigant...

10.1089/end.2009.1537 article EN Journal of Endourology 2009-09-11

Single-cell transcriptomics has been fully embraced in plant biological research and is revolutionizing our understanding of growth, development, responses to external stimuli. However, single-cell transcriptomic data analysis plants not trivial, given that there currently no end-to-end solution integration various bioinformatics tools involves a large number required dependencies. Here, we present scPlant, versatile framework for exploring atlases with minimum input provided by users. The...

10.1016/j.xplc.2023.100631 article EN cc-by-nc-nd Plant Communications 2023-05-29

The plant genome produces an extremely large collection of long noncoding RNAs (lncRNAs) that are generally expressed in a context-specific manner and have pivotal roles regulation diverse biological processes. Here, we mapped the transcriptional heterogeneity lncRNAs their associated gene regulatory networks at single-cell resolution. We generated comprehensive cell atlas whole-organism level by integrative analysis 28 published RNA sequencing (scRNA-seq) datasets from juvenile Arabidopsis...

10.1016/j.xplc.2023.100717 article EN cc-by-nc-nd Plant Communications 2023-09-15

To report our experience with minimally invasive percutaneous nephrolithotomy (mPCNL) for upper urinary tract (UUT) calculi in transplanted kidneys.Between August 2002 and June 2006, seven patients (mean age 40.7 years) UUT stones kidneys (including one staghorn, two pelvic four ureteric stones) were treated by mPCNL. A 16 F peel-away sheath was placed as the access port a 8.5/11.5 nephroscope or 8/9.8 ureteroscope used manipulation. Every 2-3 months during follow-up, had their serum urea,...

10.1111/j.1464-410x.2007.06768.x article EN BJU International 2007-02-19

To inspect the renal pelvic pressure during minimally invasive percutaneous nephrolithotomy (MPCNL) and to investigate whether use of 14 18-Fr tract, 8/9.8-Fr rigid ureteroscope, a perfusion with high furnished for MPCNL results in pressure.Between July 2005 February 2006, 76 patients were selected measurement MPCNL. The was measured by baroceptor blood channel MAIDRAY PM9000 monitor, which connected open-ended ureteric catheter indwelled pelvis retrogradely. computer collected data each...

10.1097/sle.0b013e31806e61f4 article EN Surgical Laparoscopy Endoscopy & Percutaneous Techniques 2007-08-01

Abstract Chromatin accessibility sequencing has been widely used for uncovering genetic regulatory mechanisms and inferring gene networks. However, effectively integrating large‐scale chromatin datasets posed a significant challenge. This is due to the lack of comprehensive end‐to‐end solution, as many existing tools primarily emphasize data preprocessing overlook downstream analyses. To bridge this gap, we have introduced cisDynet, holistic solution that combines streamlined using Snakemake...

10.1002/imt2.152 article EN cc-by iMeta 2023-11-01

To report our experience with minimally invasive percutaneous nephrolithotomy (MPCNL) (14-18Fr tract) to treat staghorn calculi via multiple tracts in a single session procedure, and evaluate the feasibility efficiency of this technique.From March 2001 November 2005, 100 patients were treated by MPCNL tracts. The size location stone, operative parameters, number tracts, stone-free rate, operating time, hospital stay, complications analyzed retrospectively.A total 209 established renal units...

10.1097/sle.0b013e318038faa4 article EN Surgical Laparoscopy Endoscopy & Percutaneous Techniques 2007-04-01

Aim: The management of complicated benign upper urinary tract occlusion is extremely challenging, especially in patients unable to undergo an open operative procedure. We report the long‐term results a permanent metallic stent for occlusion. Methods: From October 1995 December 1998, 13 (8 men and 5 women, with mean age 43 years) have been treated by implantation. All had nephrostomy tube relieve obstruction average time stay was 27 months, ranging from 3 131 months. length 2.7 cm, 1 3.6 cm....

10.1111/j.1442-2042.2007.01802.x article EN International Journal of Urology 2007-07-04

Objective: To report our experience of minimally invasive percutaneous nephrolithotomy(MPCNL) in managing upper urinary tract calculi complicated with severe spinal deformity. Materials and Methods: Between August 2001 to December 2012, 16 13 patients deformity were treated by MPCNL. Preoperative investigation the respiratory function, evaluation anatomy intravenous urography (IVU) CT scan, preoperative kidney ultrasonagraphy simulation puncture performed all patients. The was guided...

10.1590/s1677-5538.ibju.2015.0408 article EN cc-by International braz j urol 2016-10-01

To assess the efficacy of febuxostat combined with hydration on contrast-induced nephropathy (CIN) in coronary heart disease patients hyperuricemia undergoing percutaneous intervention (PCI).Patients who underwent PCI were randomly assigned to 2 groups. The control group was given only, and received 40 mg daily before administration contrast agent hydration. primary endpoint study incidence CIN, defined as an increase baseline serum creatinine concentration by 25% at days after media...

10.1097/md.0000000000028683 article EN cc-by-nc Medicine 2022-01-28

N-doped carbon-modified carbon nanotube/Pt-Ni alloy catalysts were prepared via a thermal decomposition of Ni-MOF with dual organic ligands (triethylene diamine and terephthalic acid). Different from the individual Pt Ni nanoparticles derived single ligand, bestow obtained Pt-Ni structure. The fabricated catalyst exhibits significant hydrogen evolution reaction activity stability in alkaline solution, an overpotential −196 mV to achieve 10 mA cm−2. Moreover, TOF value CNT/Pt-Ni is 2.1 times...

10.1246/cl.220174 article EN Chemistry Letters 2022-05-16

Abstract Chromatin accessibility sequencing has been widely used for uncovering genetic regulatory mechanisms and inferring gene networks. However, effectively integrating large-scale chromatin datasets posed a significant challenge. This is due to the lack of comprehensive end-to-end solution, as many existing tools primarily emphasize data pre-processing overlook downstream analyses. To bridge this gap, we have introduced cisDynet, holistic solution that combines streamlined using...

10.1101/2023.10.30.564662 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2023-11-02

You have accessJournal of UrologyStone Disease: New Technology/SWL, Ureteroscopic or Percutaneous Stone Removal IV1 Apr 20121934 TREATMENT OF UPPER URINARY CALCULI WITH MPCNL A SINGLE-CENTER EXPERIENCE 19 YEARS Guohua Zeng, Zanlin Mai, Jian Yuan, Xun Li, Chichang Shan, Kaijun Wu, Guanzhao Liu, Wenzhong Cheng, Bing Guo, Xiangdong Yue, Defeng Qi, Luping Wang, Wenqi Yongda Xiaogang Lu, Jintai Luo, Zhaohui He, Ming Lei, Dongliang Zhong, Wen Zhigang Zhao, Zhuoying Liang, and Suilin Lu ZengGuohua...

10.1016/j.juro.2012.02.2092 article EN The Journal of Urology 2012-04-01
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