A5048295407- Kidney Stones and Urolithiasis Treatments
- Pediatric Urology and Nephrology Studies
- Ureteral procedures and complications
- Prostate Cancer Treatment and Research
- Urinary Tract Infections Management
- Renal cell carcinoma treatment
- Bladder and Urothelial Cancer Treatments
- Renal and Vascular Pathologies
- Dialysis and Renal Disease Management
- Cancer, Lipids, and Metabolism
- Ferroptosis and cancer prognosis
- Therapeutic Uses of Natural Elements
- Circular RNAs in diseases
- Urinary Bladder and Prostate Research
- Cancer Immunotherapy and Biomarkers
- Gallbladder and Bile Duct Disorders
- Cancer-related molecular mechanisms research
- Prostate Cancer Diagnosis and Treatment
- Radiation Dose and Imaging
- Genetic and Kidney Cyst Diseases
- Urological Disorders and Treatments
- Renal and related cancers
- Biomedical Research and Pathophysiology
- Metallurgy and Material Forming
- Fluid Dynamics and Heat Transfer
Guangzhou Medical University
2016-2025
First Affiliated Hospital of Guangzhou Medical University
2016-2025
Harbin Institute of Technology
2021-2024
Aviation Industry Corporation of China (China)
2024
ICMA Centre
2022
University of Reading
2022
Guangzhou Institute of Dermatology
2019-2021
Key Laboratory of Guangdong Province
2013-2019
Guangzhou First People's Hospital
2013
Objectives To investigate the prevalence and associated factors of kidney stones among adults in China. Subjects Methods A nationwide cross‐sectional survey was conducted individuals aged ≥18 years across China, from May 2013 to July 2014. Participants underwent urinary tract ultrasonographic examinations, completed pre‐designed standardised questionnaires, provided blood urine samples for analysis. Kidney were defined as particles ≥4 mm. Prevalence proportion participants with binary...
Retrograde intrarenal surgery (RIRS) is the main treatments for upper urinary tract stones. The Ureteral Access Sheath (UAS) serves as a supplementary tool, facilitating direct kidney access during RIRS. High quality of evidence comparing tip bendable suction ureteral sheath (S-UAS) with traditional UAS in RIRS treatment renal and stones lacking. purpose study to compare efficacy safety S-UAS or ≤30 mm.
Abstract Background Elevated intrarenal pressure (IRP) during retrograde surgery (RIRS) can lead to deleterious complications. Emerging non‐invasive, real‐time IRP monitoring tools are proving crucial for enhancing procedural safety. This study evaluates a newly developed flexible and navigable suction ureteral access sheath (FANS) with capabilities through animal clinical trial, assessing its accuracy operational benefits. Methods A preclinical prospective trial involving 100 patients were...
Objective To present a novel miniature endoscopic system designed to improve the safety and efficacy of percutaneous nephrolithotomy, named ‘super‐mini nephrolithotomy’ ( SMP ). Patients Methods The consists 7‐F nephroscope with enhanced irrigation modified 10–14 F access sheath suction‐evacuation function. This was tested in patients renal stones <2.5 cm, multicentre prospective non‐randomised clinical trial. In all, 146 were accrued 14 centres. Nephrostomy tract dilatation carried out...
Abstract Background The encapsulation of circular RNAs (circRNAs) into extracellular vesicles (EVs) enables their involvement in intercellular communication and exerts an influence on the malignant advancement various tumors. However, regulatory role EVs-circRNA renal cell carcinoma (RCC) remains elusive. Methods vitro vivo functional experiments were implemented to measure effects circEHD2 phenotype RCC. EVs-circEHD2 activation fibroblasts was assessed by collagen contraction assay, western...
To compare the safety and efficacy of fluoroscopic guidance (FG), total ultrasonographic (USG), combined (CG) for percutaneous renal access in mini-percutaneous nephrolithotomy (mini-PCNL).The present study was conducted between July 2014 May 2015 as a prospective randomised trial at First Affiliated Hospital Guangzhou Medical University. In all, 450 consecutive patients with stones >2 cm were to undergo FG, USG, or CG mini-PCNL (150 each group). The primary endpoints stone-free rate (SFR)...
Background TP53 gene mutation is one of the most common mutations in human bladder cancer (BC) and has been implicated progression prognosis BC. Methods RNA sequencing data different populations platforms were downloaded from The Cancer Genome Atlas (TCGA) Gene Expression Omnibus (GEO) database to determine validate a TP53-associated immune prognostic signature (TIPS) based on differentially expressed immune-related genes (DEIGs) between muscle-invasive (MIBC) patients with without...
Epidemiological evidence of over 9000 people suggests that daily intake vinegar whose principal bioactive component is acetic acid associated with a reduced risk nephrolithiasis. The underlying mechanism, however, remains largely unknown.
Kidney stones, which have high prevalence and recurrence rates, often cause severe oxidative damage inflammation. The ultrasmall hydrodynamic diameter of nanoparticles is crucial for their enrichment in the kidneys to exert biological activity. However, integrating crystallization inhibition therapeutic functions into a single nanoparticle challenging. A novel iron (Fe)-gallic acid (Ga) metal-phenolic networks (Fe-Ga MPNs) developed treating calcium oxalate (CaOx) nephropathies. These MPNs...
hsa-miR-195-5p (miR-195) has been proven to be a critical regulator in the progression of prostate cancer (PCa). To identify additional targets and molecular functions miR-195, we overexpressed miR-195 by transient oligonucleotide transfection DU145 LNCaP cells examined effects. RNA-based microarray dual-luciferase assays were carried out novel while vitro functional assays, subcutaneous xenograft model, tissue (TMA) analysis cohort publicly available data (Taylor cohort) used investigate...
Background/Aims: Kidney renal clear cell carcinoma (KIRC) is one of the most fatal malignancies due to late diagnosis and poor treatment. To improve its prognosis, a screening for molecular biomarkers KIRC urgently needed. Long non-coding RNAs (lncRNAs) play important roles in tumorigenesis prognosis cancers. However, it not whether lncRNAs can be used as predicting survival patients. Methods: In this study, our aim was identify lncRNAs/mRNAs signatures their prognostic values KIRC. The...
To evaluate the efficacy and safety of super-mini percutaneous nephrolithotomy (SMP) in treatment pediatric kidney stones.We reviewed records 111 children with renal stones treated SMP technique four different centers between September 2014 2015. The indications for all these kids were either previously failed shock wave lithotripsy or retrograde intrarenal surgery approaches, according to their parents' preferences. Nephrostomy tracts used system ranged from 10F 14F size. Lithotripsy was...