A5101406911- Kidney Stones and Urolithiasis Treatments
- Pediatric Urology and Nephrology Studies
- Tissue Engineering and Regenerative Medicine
- Urological Disorders and Treatments
- Ureteral procedures and complications
- Electrospun Nanofibers in Biomedical Applications
- Renal and Vascular Pathologies
- Autophagy in Disease and Therapy
- Prostate Cancer Diagnosis and Treatment
- Urinary Tract Infections Management
- Chronic Kidney Disease and Diabetes
- Ferroptosis and cancer prognosis
- Uterine Myomas and Treatments
- Colorectal Cancer Surgical Treatments
- Neuroblastoma Research and Treatments
- Epigenetics and DNA Methylation
- Endometrial and Cervical Cancer Treatments
- Dialysis and Renal Disease Management
- Endometriosis Research and Treatment
- Pulmonary Hypertension Research and Treatments
- Sarcoma Diagnosis and Treatment
- Muscle and Compartmental Disorders
- Cancer Cells and Metastasis
- Glioma Diagnosis and Treatment
- Cannabis and Cannabinoid Research
Wuhan University
2014-2025
Renmin Hospital of Wuhan University
2014-2025
Henan Agricultural University
2021-2024
Henan University
2021-2024
Intuitive Surgical (United States)
2016-2022
Intuit (United States)
2022
Simcere Pharmaceutical (China)
2020-2021
Central Hospital of Zibo
2020
Intuitive Surgical (Switzerland)
2020
Health Economics and Outcomes Research (United Kingdom)
2020
Objective To present a novel miniature endoscopic system designed to improve the safety and efficacy of percutaneous nephrolithotomy, named ‘super‐mini nephrolithotomy’ ( SMP ). Patients Methods The consists 7‐F nephroscope with enhanced irrigation modified 10–14 F access sheath suction‐evacuation function. This was tested in patients renal stones <2.5 cm, multicentre prospective non‐randomised clinical trial. In all, 146 were accrued 14 centres. Nephrostomy tract dilatation carried out...
Copper (Cu) is a trace element necessary in animals as well human beings. However, excessive Cu toxic to immunocytes, but the precise mechanism largely unclear so far. This work was conducted aiming examine Cu-mediated autophagy together with its role toxicology RAW264.7 cells. Here, we demonstrated that CuSO4 reduced cell viability depending on dose. could obviously increase According obtained results, induced through Akt/AMPK/mTOR pathway which characterized by down regulation of p-Akt...
Ferroptosis is an iron‑dependent lipid peroxidation process. Although the involvement of ferroptosis in kidney diseases has recently been reported, association between and urolithiasis remains unclear. The present study examined effects on calcium oxalate (CaOx) crystal‑induced renal tubular epithelial cell injury vivo vitro. First, cells were exposed to various concentrations CaOx. By measuring viability, Fe2+ levels, levels ferroptosis‑related proteins, it was identified that relative...
<h3>Importance</h3> The cost-effectiveness of different surgical techniques for radical prostatectomy remains a subject debate. Emergence recent critical clinical data and changes in equipment costs due to their shared use by specialties necessitate an updated analysis centralized, largely government-funded health care system such as the UK National Health Service (NHS). <h3>Objective</h3> To compare robotic-assisted (RARP) with open (ORP) laparoscopic-assisted (LRP) using contemporary on...
Renal tubular epithelial cell damage is the basis for formation of kidney stones. Oxalate can induce human proximal (HK‐2) cells to undergo autophagy and ferroptosis. The present study was aimed at investigating whether ferroptosis HK‐2 induced by oxalate caused excessive activation autophagy. We treated with 2 mmol/L establish a stone model. First, we tested degree oxidative level in control group intervention group. then knocked down overexpressed BECN1 gene NCOA4 cells, followed...
One of the most prevalent urinary illnesses is kidney stone formation, often known as nephrolithiasis. The precise processes remain poorly after substantial investigation. In order to successfully prevent and cure formation recurrence, additional research into pathophysiology paramount importance. Ferroptosis linked a variety renal diseases critical factor in death cells. However, little about how ferroptosis-related genes (FRGs) contribute development stones. Database Gene Expression...
Bone marrow mesenchymal stem cells (BMSCs) represent an important source of for tissue repair. The tropism these to the sites injury and tumors has been well established. Their tumor-homing properties make BMSCs good candidates as antitumor agent delivery vehicles. In this study, we showed that have ability migrate toward various cancer cells, including prostate in vitro vivo incorporating into tumor mass. When infected with herpes simplex virus thymidine kinase (TK) gene by lentiviral...
Transient receptor potential vanilloid 3 (TRPV3) is a member of the TRP channels family Ca2+ -permeant cation channels. In this study, we aim to investigate role TRPV3 in pulmonary vascular remodeling and PASMCs proliferation under hypoxia.The expression was evaluated patients with arterial hypertension (PAH) hypoxic rats, using hematoxylin eosin (H&E) immunohistochemistry. vitro, MTT assay, flow cytometry, Western blotting immunofluorescence were performed effects on PASMCs.We found that,...
We sought to evaluate trends and clinical economic outcomes between robotic-assisted lobectomy (RL), video-assisted thoracoscopic (VL), open pulmonary (OL).Patients who underwent a for malignancy from January 1, 2008, September 30, 2015, were identified in the Premier Healthcare Database. Propensity score matched (PSM) comparisons performed RL versus VL OL. Patient characteristics applied generate propensity scores. In-hospital perioperative 30-day costs compared within cohorts.From 2008...
Background: Deposition of various crystal and organic substances in the kidney can lead to stone formation. Melatonin is an effective endogenous antioxidant that prevent crystalluria damage due formation aggregation. In this study, we investigated mechanism by which melatonin inhibits endoplasmic reticulum (ER) stress apoptosis.Methods: We treated HK-2 cells with oxalate establish vitro model, these different concentrations (0, 5, 10, 20 μmol/L) AMP-activated protein kinase (AMPK) inhibitor...
Conversion rates during minimally invasive surgery are generally examined in the limited scope of a particular procedure. However, for hospital or payor, cumulative impact conversions commonly performed procedures could have much larger negative effect than what is appreciated by individual surgeons. The aim this study to assess open conversion (MIS) across common using laparoscopic/thoracoscopic (LAP/VATS) and robotic-assisted (RAS) approaches.
Oxalate is an organic dicarboxylic acid that a common component of plant foods. The kidneys are essential organs for oxalate excretion, but excessive oxalates may induce kidney stones. Jupiter microtubule associated homolog 2 (JPT2) critical molecule in Ca2+ mobilization, and its intrinsic mechanism exposure stones remains unclear. This study aimed to reveal the JPT2 Genetic approaches were used control expression cells mice, action was analyzed using transcriptomics untargeted metabolomics....
Polyporus umbellatus sclerotia have been used as a diuretic agent in China for over two thousand years. A shortage of the natural P. has prompted researchers to induce sclerotial formation laboratory.
Central nervous system (CNS) embryonal tumors (WHO grade IV) are a heterogeneous group of rare, poorly differentiated neuroepithelial malignant neoplasms that commonly occur in children, and they have poor prognosis. The 2016 WHO (World Health Organization) classification CNS created major shift paradigm the tumors. However, some cases were still difficult to classify. Further integrative genomic analysis is needed improve precise classification, diagnosis treatment Herein, we firstly report...