Chu Ann Chai

ORCID: 0000-0001-8915-3617
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About
Contact & Profiles
Research Areas
  • Kidney Stones and Urolithiasis Treatments
  • Pediatric Urology and Nephrology Studies
  • Ureteral procedures and complications
  • Cardiac, Anesthesia and Surgical Outcomes
  • Renal and Vascular Pathologies
  • Abdominal Surgery and Complications
  • Infectious Disease Case Reports and Treatments
  • Radiation Dose and Imaging
  • Paleopathology and ancient diseases
  • Diverticular Disease and Complications
  • Appendicitis Diagnosis and Management
  • Anorectal Disease Treatments and Outcomes
  • Healthcare Systems and Challenges
  • Healthcare cost, quality, practices
  • Hedgehog Signaling Pathway Studies
  • Aortic aneurysm repair treatments
  • Colorectal Cancer Surgical Treatments
  • Traumatic Ocular and Foreign Body Injuries
  • Surgical site infection prevention
  • Nonmelanoma Skin Cancer Studies
  • Pelvic and Acetabular Injuries
  • COVID-19 and healthcare impacts
  • Health, Medicine and Society
  • Gallbladder and Bile Duct Disorders
  • Global Health and Surgery

University Malaya Medical Centre
2021-2025

University of Malaya
2020-2025

First Affiliated Hospital of Guangzhou Medical University
2024

Guangzhou Medical University
2024

University of Göttingen
2022

University of Birmingham
2022

National Institute for Health Research
2022

Retrograde intrarenal surgery (RIRS) is the main treatments for upper urinary tract stones. The Ureteral Access Sheath (UAS) serves as a supplementary tool, facilitating direct kidney access during RIRS. High quality of evidence comparing tip bendable suction ureteral sheath (S-UAS) with traditional UAS in RIRS treatment renal and stones lacking. purpose study to compare efficacy safety S-UAS or ≤30 mm.

10.1016/j.eclinm.2024.102724 article EN cc-by-nc-nd EClinicalMedicine 2024-07-05

The ureteral access sheath (UAS) has been a boon and bane in flexible ureteroscopy (FURS), with its merits demerits well established. Its design dimensions were instrumental reshaping the way scopes used key adjuncts to establishing retrograde intrarenal surgery (RIRS) as standard of care endourological management renal stones. With ever-changing landscape RIRS over decades shaped by technological advancements lasers scopes, UAS also continuously evolved. utility suction endourology recently...

10.3390/diagnostics14101034 article EN cc-by Diagnostics 2024-05-16

Abstract Background Elevated intrarenal pressure (IRP) during retrograde surgery (RIRS) can lead to deleterious complications. Emerging non‐invasive, real‐time IRP monitoring tools are proving crucial for enhancing procedural safety. This study evaluates a newly developed flexible and navigable suction ureteral access sheath (FANS) with capabilities through animal clinical trial, assessing its accuracy operational benefits. Methods A preclinical prospective trial involving 100 patients were...

10.1002/ctd2.70031 article EN cc-by Clinical and Translational Discovery 2025-01-21

To evaluate the perioperative outcomes of retrograde intra-renal surgery (RIRS) for lower pole stones (LPS) and factors affecting stone-free rate (SFR).Data from 20 centers were retrospectively reviewed. Inclusion criteria adult patients, normal renal anatomy, LPS. Exclusion bilateral surgery, concomitant ureteral stones. SFR was defined as a single residual fragment (RF) ≤ 2 mm evaluated 3-months after surgery. A multivariable logistic regression analysis performed to assess associated with...

10.1007/s00345-023-04363-6 article EN cc-by World Journal of Urology 2023-03-17

Abstract Purpose To assess the 30-day stone-free rate and peri-operative outcomes of flexible ureteroscopy (FURS) with navigable suction ureteral access sheaths (FANS) in adults undergoing same-sitting bilateral retrograde intrarenal surgery (SSB-RIRS). Methods Prospectively data 115 adult patients kidney stone disease SSB-RIRS across 14 global centers between July 2023 March 2024 were analyzed. Patient demographics, characteristics operative recorded. A low-dose non contrast CT scan was...

10.1007/s00345-025-05477-9 article EN cc-by World Journal of Urology 2025-02-28

Background: Assessment of residual fragments (RFs) is a key step after treatment kidney stones. Objective: To evaluate differences in RFs estimation based on unenhanced computerized tomography (CT) versus X-rays/ultrasound retrograde intrarenal surgery (RIRS) for Design: A retrospective analysis data from 20 centers adult patients who had RIRS was done (January 2018–August 2021). Methods: Exclusion criteria: ureteric stones, anomalous kidneys, bilateral renal Patients were divided into two...

10.1177/17562872231198629 article EN cc-by-nc Therapeutic Advances in Urology 2023-01-01

With several single-use ureteroscopes now available, our aim was to analyze and compare data obtained globally from high-volume centers using both disposable reusable flexible see if indeed in real-world practice either scope has a distinct advantage.Retrospective analysis performed on the FLEXOR registry, which created as TOWER group (Team of Worldwide Endourological Researchers, research wing Society) endeavor. Patients who underwent retrograde intrarenal surgery (RIRS) for renal stones...

10.1177/17562872231158072 article EN cc-by-nc Therapeutic Advances in Urology 2023-01-01

Retrograde Intrarenal Surgery (RIRS) is recommended as an alternative to percutaneous nephrolithotomy for stones up 2 cm. Pre-stenting before RIRS remains controversial with various studies differing in outcomes and recommendations. We aim understand how pre-stenting influences surgical outcomes.A number of 6579 patients from the TOWER group registry were divided into pre-stented (group 1) non-pre-stented groups 2). Patients aged ≥18 years old, normal calyceal anatomy enrolled. ureteric...

10.23736/s2724-6051.23.05239-4 article EN Minerva Urology and Nephrology 2023-06-09

Traditionally, bilateral urolithiasis treatment involved staged interventions due to safety concerns. Recent studies have shown that same-sitting retrograde intrarenal surgery (SSB-RIRS) is effective, with acceptable complication rates. However, there's no clear data on the optimum laser for procedure. This study aimed assess outcomes of SSB-RIRS comparing thulium fiber (TFL) and high-power holmium:yttrium-aluminum-garnet (Ho:YAG) in a multicenter real-world practice.

10.4111/icu.20240185 article EN cc-by-nc Investigative and Clinical Urology 2024-01-01

Guidelines advocate cystoscopy surveillance (CS) for non-muscle invasive bladder cancer (NMIBC) post-resection. However, is operator dependent and may miss upper tract lesions or carcinoma

10.3389/fsurg.2021.659292 article EN cc-by Frontiers in Surgery 2021-05-13
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