Wei Zhu

ORCID: 0000-0001-5796-4167
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Research Areas
  • Heart Rate Variability and Autonomic Control
  • Cardiac Ischemia and Reperfusion
  • Impact of Technology on Adolescents
  • Simulation-Based Education in Healthcare
  • Heavy Metal Exposure and Toxicity
  • Dermatology and Skin Diseases
  • Digital Mental Health Interventions
  • Exercise and Physiological Responses
  • Mitochondrial Function and Pathology
  • Allergic Rhinitis and Sensitization
  • Cardiac electrophysiology and arrhythmias
  • Occupational Health and Performance
  • Artificial Intelligence in Healthcare and Education
  • Cardiovascular and exercise physiology
  • Surgical Simulation and Training
  • Thermoregulation and physiological responses
  • Autophagy in Disease and Therapy
  • Mental Health via Writing
  • Automotive and Human Injury Biomechanics
  • Steroid Chemistry and Biochemistry
  • Health disparities and outcomes
  • Aluminum toxicity and tolerance in plants and animals
  • Calcium signaling and nucleotide metabolism
  • Technology Use by Older Adults
  • Media Influence and Health

Guangzhou Center for Disease Control and Prevention
2021-2025

First Affiliated Hospital of Guangzhou Medical University
2025

Guangzhou Medical University
2025

Southern Medical University
2025

Air Force Medical University
2024

Xinyang Normal University
2023-2024

Soochow University
2014-2017

Second Affiliated Hospital of Soochow University
2014-2017

Shanghai Advanced Research Institute
2017

Guangdong General Hospital
2016

Abstract Context Accumulating evidence implies that sleep disturbance is involved in metabolic disorders. Objective We comprehensively evaluated the association between various dimensions of behaviors and risk for dysfunction–associated fatty liver disease (MAFLD). Methods In this cross-sectional study 5011 participants with self-reported radiologically diagnosed MAFLD, a comprehensive healthy score was generated to evaluate associations MAFLD using multivariate logistic regression adjusting...

10.1210/clinem/dgac428 article EN The Journal of Clinical Endocrinology & Metabolism 2022-07-28

Autophagy has emerged as a powerful process in the response to cellular injury. The present study was designed investigate signal transduction pathways angiotensin II (Ang II)-induced autophagy. Rat vascular smooth muscle cells (VSMCs) were stimulated with different doses of Ang (10(-9)-10(-5) mol/L) for time periods (6-72 h). Incubation increased production reactive oxygen species (ROS), LC3-II LC3-I ratio, beclin-1 expression, and decreased SQSTM1/p62 expression dose- time-dependent...

10.1007/s00395-014-0416-y article EN cc-by Basic Research in Cardiology 2014-05-22

<title>Abstract</title> <bold>Background:</bold>The rapid expansion of social media has given rise to a myriad challenges among college students facing psychological distress. An abundance fragmented and repetitive information, often referred as information overload, inundates users on platforms. This inundation presents significant hurdles for experiencing distress when acquiring processing information. study investigates the associative mechanisms between overload in context avoidance...

10.21203/rs.3.rs-3909071/v1 preprint EN cc-by Research Square (Research Square) 2024-02-01

We aimed to evaluate the effect of melatonin on myocardial cell oncosis in ischemia/reperfusion injury rat, and role mitochondrial permeability transition pore (MPTP) therein.Sprague Dawley rats (N = 60) were randomly divided into five groups 12 each: control, (I/R), treatment (MT), + atractyloside (MT+ATR), (ATR).We prepared model by reperfusion after left anterior descending coronary artery was ligated for 30 min.The MT given a 10 mg/kg intravenous injection immediately thereafter; MT+ATR...

10.4238/2015.july.3.24 article EN Genetics and Molecular Research 2015-01-01

Abstract Background The utilization of short videos by individuals often leads to the emergence information exchange behavior. Previous studies have shown that certain students with psychological disorders exhibit addictive tendencies towards video-related software. Therefore, it is essential address psychology and behavior college while engaging videos. This study aims explore mechanism video interaction among disorders. Methods We conducted semi-structured interviews 30 afflicted in a...

10.1186/s12889-023-17211-4 article EN cc-by BMC Public Health 2023-11-16

Objective:The renin-angiotensin system (RAS) and renal sympathetic nerve (RSNS) are involved in the development of hypertension.The present study is designed to explore possible roles RAS RSNS foot shock-induced hypertension.Methods: Male Sprague-Dawley rats were divided into six groups: control, shock, denervation, denervation plus Captopril (angiotensin I converting enzyme inhibitor, ACE inhibitor) Tempol (superoxide dismutase mimetic) shock.Rats received shock for 14 days.We measured...

10.7150/ijbs.10250 article EN cc-by-nc International Journal of Biological Sciences 2015-01-01

Objective: To explore the relationship of sleep quality and duration with hypertension among adults aged 30-79 years old in Guangzhou. Methods: According to multi-stage stratified cluster sampling, 12 747 residents were sampled surveyed Guangzhou from January 2018 March 2019. Data on general demographic characteristics, quality, collected through questionnaire survey, Pittsburgh index (PSQI) physical examination. Multivariate logistic regression models used analyze putative association...

10.3760/cma.j.cn112150-20210204-00125 article EN Zhonghua yufang yixue zazhi 2021-07-06

Purpose: Acupoint autohemotherapy (A-AHT) has been proposed as an alternative and complementary treatment for atopic dermatitis (AD), yet the exact role of its blood component in terms therapeutic efficacy mechanism action is still largely unknown. Methods: This study aimed to evaluate efficacies mechanisms intramuscular injections autologous whole (AWB) mouse immunoglobulin G (IgG) (autologous or heterologous) at acupoints on 2,4-dinitrochlorobenzene (DNCB)-induced AD models. Serum levels...

10.2147/jir.s454325 article EN cc-by-nc Journal of Inflammation Research 2024-05-01

Background: Epinephrine was recently shown to induce a hypotension episode. Activation of β2-adrenoceptors with smooth muscle relaxation may be the underlying mechanism. This study investigated effects ICI 118551, antagonist, on epinephrine-induced blood pressure reduction via different administration routes in rats. Methods: A total 144 Sprague Dawley rats were equally randomized into 3 groups (intranasal, intravenous, and intra-arterial administration), each 4 subgroups: saline + saline,...

10.1097/fjc.0b013e3182a1e118 article EN Journal of Cardiovascular Pharmacology 2013-08-14

The aim of the present study was to assess how genetically increased Sarcoplasmic reticulum Ca2+-ATPase (Serca2a) expression affects cardiac injury after Ischemia/Reperfusion (I/R) exposure and related mechanisms involved.Rats were subjected Left Anterior Descending coronary artery (LAD) occlusion for 30 min followed by a 24-hour reperfusion. Cardiac function analysis revealed that dramatically improved in Serca2a transgenic rats, (Serca2aTG) compared Wild Type (WT) rats. Serca2aTG rats...

10.2174/1566523217666171110175251 article EN Current Gene Therapy 2017-12-12

<title>Abstract</title> Background The potential category analysis method was used to explore the categories of adolescents' cognitive impairment in Internet use, and differences influencing factors adolescents with different characteristics use each scale were analyzed. Method Potential classify disordered multiple classification logistic regression analyze effects various on categories. Result Adolescents' can be divided into four types, among which 19.61% are avoidance self-satisfaction...

10.21203/rs.3.rs-4946574/v1 preprint EN Research Square (Research Square) 2024-09-18

Elderly patients undergoing dental extraction are particularly susceptible to delayed cognitive recovery after sedation. This study aimed compare the effects of remimazolam and midazolam on early postoperative in elderly extraction.

10.2147/dddt.s491223 article EN cc-by-nc Drug Design Development and Therapy 2024-12-01

You have accessJournal of UrologyLate-Breaking Abstracts (LBA1)1 Apr 2020LBA01-05 SIMULATION IN UROLOGICAL TRAINING AND EDUCATION (SIMULATE): AN INTERNATIONAL RANDOMISED CONTROLLED CLINICAL EDUCATIONAL TRIAL TO DETERMINE THE EFFECT OF SIMULATION-BASED SURGICAL Abdullatif Aydin*, Kamran Ahmed, Mieke Van Hemelrijck, Hashim Takashige Abe, Wei Zhu, John Sfakianos, Ali Serdar Gözen, Thomas Kunit, Andreas Skolarikos, Nicholas Raison, Felix Moltzahn, Knoll, Andrea Lantz, Ahmed Al-Jabir, Oliver...

10.1097/ju.0000000000000946.05 article EN The Journal of Urology 2020-04-01

Describing the pattern of pediatric eye diseases is necessary for appropriate care in children. This study explored spectrum and characteristics ophthalmic a typical tertiary ophthalmology hospital China.A retrospective was conducted at between 2010 2019 Guangzhou, China. included 44,552 inpatients who were younger than 18 years old. Demographic diagnostic data collected from electronic medical record system. Multiphase regression analysis used to estimate trends annual percentages ten...

10.1186/s12886-022-02533-5 article EN cc-by BMC Ophthalmology 2022-07-19

// Yi-Cun Chen 1 , Wei Zhu 4 Shu-Ping Zhong 2 Fu-Chun Zheng 3 Fen-Fei Gao Yan-Mei Zhang Han Xu Yan-Shan Gang-Gang Shi 1, 5 Department of Pharmacology, Shantou University Medical College, 515041, Guangdong, China Biochemistry and Molecular Biology, Keck School Medicine, Southern California, Los Angeles, California 90033, USA Pharmacy, the First Affiliated Hospital, Geneheal Biotechnology Co., Ltd, Guangzhou 510000, Cardiovascular Diseases, Correspondence to: Shi, e-mail: ggshi@stu.edu.cn...

10.18632/oncotarget.6086 article EN Oncotarget 2015-10-19

Background: Experiments in rodents have shown that hypoxic preconditioning (HP) can increase the therapeutic effectiveness of transplanted bone-marrow mesenchymal stem cells (MSCs) for myocardial infarction (MI). Here, we investigated whether benefits associated with HP-MSC transplantation are also observed non-human primates MI. Methods: Allogeneic MSCs engineered to express GFP via lentiviral transfection were cultured 21% oxygen (N-MSCs) or 0.5% (HP-MSCs) 24 hours. MI was surgically...

10.1161/circ.132.suppl_3.15053 article EN Circulation 2015-11-10

Objective To investigate the change features in physical performance of helicopter aviators who stayed onboard for a prolonged time,to develop schemes training directed at shipboard and finally to analyze assess effects intervention schemes,through detection parameters different stages deployment.Methods Fiftyeight from batches escort personnel Gulf Aden were selected as our research subjects.Bilateral gripping power,lumboabdominal muscle strength,PWC170,amplitude variations body mass index...

10.3760/cma.j.issn.1009-6906.2014.06.006 article EN Chin J Naut Med & Hyperbar Med 2014-12-28
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