A5100762489- Pediatric Urology and Nephrology Studies
- Kidney Stones and Urolithiasis Treatments
- Acute Kidney Injury Research
- Dialysis and Renal Disease Management
- Plant Virus Research Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Mitochondrial Function and Pathology
- Cancer Diagnosis and Treatment
- Adipose Tissue and Metabolism
- Organ Donation and Transplantation
- Cancer Research and Treatments
- Cardiac Ischemia and Reperfusion
- Renin-Angiotensin System Studies
- Bone Tumor Diagnosis and Treatments
- Geochemistry and Geologic Mapping
- Oral and Maxillofacial Pathology
- Cancer Immunotherapy and Biomarkers
- Urological Disorders and Treatments
- Lung Cancer Research Studies
- Chronic Kidney Disease and Diabetes
- Tracheal and airway disorders
- Renal cell carcinoma treatment
- Geological and Geochemical Analysis
- Abdominal Surgery and Complications
- Hip and Femur Fractures
Zhejiang University
2002-2025
First Affiliated Hospital Zhejiang University
2013-2024
Zhejiang Center for Disease Control and Prevention
2024
Shanghai Clinical Research Center
2024
Xiangya Hospital Central South University
2013-2024
Central South University
2012-2024
First Hospital of Jilin University
2016-2023
Jilin University
2012-2023
Army Medical University
2022
Shandong Provincial QianFoShan Hospital
2021
Gut microbiota produce Trimethylamine N-oxide (TMAO) by metabolizing dietary phosphatidylcholine, choline, l-carnitine and betaine. TMAO is implicated in the pathogenesis of chronic kidney disease (CKD), diabetes, obesity atherosclerosis. We test, whether augments angiotensin II (Ang II)-induced vasoconstriction hence promotes Ang II-induced hypertension. Plasma levels were indeed elevated hypertensive patients, thus potential pathways which mediates these effects explored. (400...
Retrograde intrarenal surgery (RIRS) is the main treatments for upper urinary tract stones. The Ureteral Access Sheath (UAS) serves as a supplementary tool, facilitating direct kidney access during RIRS. High quality of evidence comparing tip bendable suction ureteral sheath (S-UAS) with traditional UAS in RIRS treatment renal and stones lacking. purpose study to compare efficacy safety S-UAS or ≤30 mm.
The primary aim of this study was to determine whether hypophosphatemia during continuous veno-venous hemofiltration (CVVH) is associated with the global outcome critically ill patients acute kidney injury (AKI).760 diagnosed AKI and had received CVVH therapy were retrospectively recruited. Death 28-day period survival at 28 days after initiation used as endpoints. Demographic clinical data including serum phosphorus levels recorded along outcome. Hypophosphatemia defined according...
Abstract Background Bean pod mottle virus (BPMV) is a wide-spread and destructive that causes huge economic losses in many countries every year. A sensitive, reliable specific method for rapid surveillance urgently needed to prevent further spread of BPMV. Methods degenerate reverse-transcription loop-mediated isothermal amplification (RT-LAMP) primer set was designed on the conserved region BPMV CP gene. The reaction conditions RT-LAMP were optimized feasibility, specificity sensitivity...
Inguinal lymph node metastasis (LNM) is one of the most significant prognostic factors for patients with penile cancer. This study aimed to identify potential predictors inguinal LNM.A comprehensive search PubMed, Embase, and Cochrane Library databases studies that reported LNM in cancer was performed. Finally, we selected 42 eligible 4,802 patients. Accumulative analyses odds ratios (ORs) corresponding 95% confidence intervals (CIs) were All performed by using Review Manager software...
Abstract Aims Acute kidney injury (AKI), a major health burden, lacks effective therapy. Anti‐inflammatory actions of disintegrin and metalloproteinase with thrombospondin type 1 motif member 13 (ADAMTS13) may provide new treatment option for AKI. Along inflammation, oxidative stress is critical AKI development, yet the impact ADAMTS13 on in remains to be fully elucidated. Methods We assess recombinant human (rhADAMTS13) murine ischaemia/reperfusion (IR) model. Antioxidant stress‐enzyme...
A myokine secreted by skeletal muscles during exercise called irisin mitigates ischemia-reperfusion (I/R) injury in epithelial cells of various organs limiting damage to mitochondria. We test whether may preserve the mitochondrial integrity and function renal tubular protect against ischemia-reperfusion-induced acute kidney (AKI).
Purpose: To evaluate the dynamics of early serum tumour markers (STMs) and neutrophil-to-lymphocyte ratio (NLR) to predict clinical efficacy prognosis advanced non-small-cell lung cancer (NSCLC) patients who received programmed cell death-1 (PD-1)/programmed death-ligand 1 (PD-L1) inhibitors. Patients Methods: We retrospectively reviewed with NSCLC treated PD-1/PD-L1 inhibitors between September 2017 August 2020. NLR STMs were routinely measured immunotherapy initiation first radiological...
Inadequate oxygen availability may lead to impairment of neurocognitive functions. The aim the present study was investigate effect acute high-altitude exposure on cerebral hemodynamic response and working memory.The same subjects performed memory exercises with forward backward digit span tasks both under normal conditions in large simulated hypobaric hypoxia chambers, a series physiological parameters were evaluated. Functional near-infrared spectroscopy used measure blood flow changes...
Acute kidney injury (AKI) causes multiple organ dysfunction. Here, we identify a possible mechanism that can drive brain vessel after AKI. We induced 30-minute bilateral renal ischemia-reperfusion in C57Bl/6 mice and isolated microvessels macrovessels 24 hours or 1 week later to test their responses vasoconstrictors found AKI vessels were sensitized Ang II (angiotensin II). Upregulation of FGF2 (fibroblast growth factor 2) FGFBP1 (FGF binding protein 1) expression both serum tissue suggested...
Reduced A Disintegrin And Metalloproteinase with a ThromboSpondin type 1 motif member 13 (ADAMTS13) levels are observed in kidney disease. We test whether recombinant human ADAMTS13 (rhADAMTS13) mitigates renal injury chronic disease (CKD) and the potential mechanisms.CKD was established 3 months after ischaemia/reperfusion (IR). von Willebrand factor (vWF) levels, function morphological changes were analysed. Afferent arteriolar responses to angiotensin II (Ang II) acetylcholine (ACh)...
Aphasia is a common symptom encountered by neurologists. However, the presence of aphasia as sole manifestation partial status epilepticus rare. The present study reports case aphasic in 27-year-old right-handed female who presented after abrupt onset aphasia, which had persisted for 1.5 days. patient's medical history included head trauma followed craniectomy and cranioplasty. Computed tomography scans revealed lesion left parietal lobe, an electroencephalogram showed spike slow wave...
In patients with renal disease, high serum phosphate shows a relationship cardiovascular risk. We speculate that (HP) impairs arterial vasodilation via the endothelium and explore potential underlying mechanisms. Isolated vessel relaxation, endothelial function, glomerular filtration rate (GFR), oxidative stress status protein expression were assessed in HP diet mice. Mitochondrial function HP-treated human umbilical vein cells (HUVECs). High (1.3%) for 12 weeks impaired...
This study aimed to analyze changes the drug spectrum and clinicopathological features of drug-induced acute kidney injury (AKI) with recent medication habits changes.A retrospective analysis characteristics patients diagnosed AKI from January 2012 October 2016 period at First Affiliated Hospital Medical College Zhejiang University was conducted.Between 2016, 909 were AKI. Of these, 228 drug-related engaged in this study, including 51 who underwent renal biopsies, 74 treated antibacterial...
Thyroglossal duct cyst (TGDC) is a congenital neck malformation, with rate of approximately 7% in paediatric patients. TGDC rarely detected infants aged younger than 1 year. Even though histologically benign, it associated preterm delivery or sudden infant death due to airway obstruction, mortality 30% 40%. We report rare case neonate who presented large left lateral mass. At 7 8 months gestation, magnetic resonance imaging the foetal showed that there was high possibility cervical cystic...
Abstract Magnetite, as a genetic indicator of ores, has been studied in various deposits the world. In this paper, we present textural and compositional data magnetite from Qimantag metallogenic belt Kunlun Orogenic Belt China, to provide better understanding formation mechanism genesis shed light on analytical protocols for situ chemical analysis magnetite. Magnetite samples occurrences, including ore‐related granitoid pluton, mineralised endoskarn vein–type iron ores hosted marine...