A5102742530- Plant Pathogens and Fungal Diseases
- Polysaccharides and Plant Cell Walls
- Plant-Microbe Interactions and Immunity
- Plant Stress Responses and Tolerance
- Natural product bioactivities and synthesis
- Nitric Oxide and Endothelin Effects
- Orthodontics and Dentofacial Orthopedics
- Plant pathogens and resistance mechanisms
- Plant Disease Resistance and Genetics
- Renin-Angiotensin System Studies
- GABA and Rice Research
- Phytochemical Studies and Bioactivities
- Plant Pathogenic Bacteria Studies
- Glycosylation and Glycoproteins Research
- High Altitude and Hypoxia
- Arsenic contamination and mitigation
- Effects and risks of endocrine disrupting chemicals
- Acute Kidney Injury Research
- Cancer, Hypoxia, and Metabolism
- Temporomandibular Joint Disorders
- dental development and anomalies
- Laser Applications in Dentistry and Medicine
- Steroid Chemistry and Biochemistry
- Estrogen and related hormone effects
- Neuroscience of respiration and sleep
Guangzhou University of Chinese Medicine
2025
Zhejiang University
2018-2025
Rice Research Institute
2024
Ministry of Agriculture and Rural Affairs
2022-2024
Guangdong Academy of Agricultural Sciences
2024
Jishou University
2024
National Clinical Research Center for Digestive Diseases
2024
Hubei Academy of Agricultural Sciences
2014-2024
Tianjin Chest Hospital
2024
Tianjin University
2024
Potentilla anserina L polysaccharide (PAP) possesses many bioactivities. In the present study, molecular weight, monosaccharide composition, FT-IR, morphology of PAPs were characterized, result showed that Mw PAP-1, PAP-2, PAP-3, PAP-4, and PAP-5 4.480 × 105 Da , 1.284 Da, 8.377 104 3.639 2.412 Da; composed Rha, Man, Glc Gal. And then, ROS, MDA, SOD, GSH-Px evaluated after radiation damage by γ-rays in RAW264.7 cells. The results demonstrated reduce ROS MDA content, increase activity SOD...
<title>Abstract</title> Cellular senescence is a key element in the development of chronic kidney disease (CKD) following acute injury (AKI). However, mechanisms behind cellular remain unclear. Here, we establish an association between Pannexin1 (Panx1) and senescence. We first confirm this both natural aging AKI-CKD murine models, as well by manipulating Panx1 expression renal cells mice. then explore role non-canonical Panx1, calcium (Ca<sup>2+</sup>) leak channel endoplasmic reticulum...
Lead (Pb) widely exists in the water environment and has severe toxic effects on aquatic organisms. The yellow catfish (Pelteobagrus fulvidraco) is one of most important commercial species China, moreover, its natural populations are declining with degradation environmental quality. However, little known about Pb immune organs. This study was performed to determine waterborne exposure bioaccumulation, histomorphology, antioxidant status, apoptotic response head kidney spleen catfish....
High-altitude pulmonary edema (HAPE) is a life-threatening disease occurs in hypobaric hypoxia (HH) environment, which could be treated by Dexamethasone, but might cause side-effects. Potentilla anserina L polysaccharide (PAP) holds promising physiological and pharmacological properties beneficial for HAPE treatment. In our study, the anti-hypoxia effect of PAP was firstly investigated through anti-normobaric test anti-acute test. Then we established model measured lung water content,...
Background: To provide tacrolimus is first-line treatment after liver and kidney transplantation. However, hypertension nephrotoxicity are common side effects that limit its use. Although tacrolimus-related well known, the underlying mechanisms not. Here, we test whether tacrolimus-induced involves RhoA (Ras homolog family member A)/ROCK (Rho-associated protein kinase) pathway in male C57Bl/6 mice. methods: Intra-arterial blood pressure was measured under anesthesia. The reactivity of renal...
Introduction The bulb of Fritillaria hupehensis , a traditional cough and expectorant medicine, is usually harvested from June to September according cultivation experience, without practical scientific guidance. Although steroidal alkaloid metabolites have been identified in F. the dynamic changes their levels during development molecular regulatory mechanisms are poorly understood. Methods In this study, integrative analyses bulbus phenotype, bioactive chemical investigations, metabolome...
The paraspinal muscle fat infiltration and osteoporotic vertebral compression fractures (OVCFs) are common degenerative diseases of the skeletal system in elderly population, which seriously affect quality life. In recent years, many studies have focused on relationship between lumbar diseases. However, impact this extrinsic factor progression OVCFs has not yet received sufficient attention clinical practice. This article summarizes imaging characteristics relevance OVCFs, aiming to provide...
Acute kidney injury (AKI) is a serious condition without efficient therapeutic options. Recent studies have indicated that recombinant human disintegrin and metalloprotease with thrombospondin motifs 13 (rhADAMTS13) provides protection against inflammation. Therefore, we hypothesized ADAMTS13 might protect AKI by reducing Bilateral renal ischemia-reperfusion (I/R) was used as models in this study. Prophylactic infusion of rhADAMTS13 employed to investigate potential mechanisms protection....
Mercury (Hg) is a global environmental contaminant, and excessive mercury levels in water can adversely affect the growth of fish. Silver carp (Hypophthalmichthys molitrix) one important freshwater aquaculture fish China, its natural resources have been critically declining. However, effects Hg2+ exposure on hormone/insulin-like factor (GH/IGF) axis toxic mechanism are still unclear. In this study, we systematically evaluated bioaccumulation, histomorphology, antioxidant status, hormone...
From April to November 2016, two outbreaks of epidemic keratoconjunctivitis (EKC) occurred successively at primary and middle schools in the Tibet Autonomous Region China, a total 197 clinically diagnosed cases were reported. Real-time PCR analyses confirmed that human adenovirus (HAdV) infection was related these outbreaks. Further studies involving sequence determination phylogenetic analysis based on penton base, hexon, fiber genes indicated type 8 (HAdV-8), belonging species D,...
Abstract Aims Acute kidney injury (AKI), a major health burden, lacks effective therapy. Anti‐inflammatory actions of disintegrin and metalloproteinase with thrombospondin type 1 motif member 13 (ADAMTS13) may provide new treatment option for AKI. Along inflammation, oxidative stress is critical AKI development, yet the impact ADAMTS13 on in remains to be fully elucidated. Methods We assess recombinant human (rhADAMTS13) murine ischaemia/reperfusion (IR) model. Antioxidant stress‐enzyme...
Abstract The dried rhizomes of Coptis chinensis hold significance in Chinese medicine. Monocropping C. under the shade a manmade scaffold, primary planting mode, poses threat to ecological balance. In recent years, practice chinensis–Cunninghamia lanceolata understory cultivation has gained prevalence southwest China. However, there is no evidence suggest that enhances viability, yield, or isoquinoline alkaloid content . This study examined physiological properties, yield indicators, and...
Sclerotium rolfsii is a fungi pathogen of southern blight with broad host range. The quinone outside inhibitor fungicide pyraclostrobin was officially approved for controlling many diseases in 2015. In this study, baseline sensitivity S. to established by measuring the 50% effective concentration (EC50) values 155 isolates rolfsii. EC50 ranged from 0.0291 1.0871 µg/ml, mean 0.4469 ± 0.2490 µg/ml (mean standard deviation). preventive vitro experiment and field experiment, efficacy reached 90%...
Fritillaria hupehensis , a well-known medicinal perennial herb, is used as an antitussive and expectorant. Continuous cropping monoculture cultivation usually negativly affect the growth of F. . Compared with system, - Magnolia officinalis intercropping system significantly increases yield However, changes in steroidal alkaloid metabolites (the most important bioactive components) their molecular regulatory mechanisms remain unclear. We performed comparative transcriptomic metabolomic...
This study investigates an aqueous salt process (ASP) combined with microwave-assisted extraction (MAE) for the seed oil from yellow horn (Xanthoceras sorbifolium Bunge). The NaCl concentration in affected yield. Box-Behnken design (BBD) and response surface methodology (RSM) were used to optimize process. optimal operating parameters were: 24 g/L NaCl, 300 W microwave power, 4:1 water material ratio, 80 min time, 45 °C temperature. chemical composition of extracted was analyzed using gas...