A5082899196- Viral Infections and Vectors
- Gut microbiota and health
- Viral Infections and Immunology Research
- Plant Stress Responses and Tolerance
- Fire effects on ecosystems
- Heavy metals in environment
- Respiratory viral infections research
- Probiotics and Fermented Foods
- Viral Infections and Outbreaks Research
- Viral gastroenteritis research and epidemiology
- Virus-based gene therapy research
- Animal Virus Infections Studies
- RNA Research and Splicing
- Poxvirus research and outbreaks
- Animal Disease Management and Epidemiology
- Bioenergy crop production and management
- Infection Control and Ventilation
- Herpesvirus Infections and Treatments
- Clostridium difficile and Clostridium perfringens research
- Plant Micronutrient Interactions and Effects
- Salivary Gland Disorders and Functions
- Real-time simulation and control systems
- Nitrogen and Sulfur Effects on Brassica
- Plant Molecular Biology Research
- RNA and protein synthesis mechanisms
Xian Center for Disease Control and Prevention
2014-2025
Shaanxi University of Chinese Medicine
2017-2025
Shaanxi Blood Center
2024-2025
Beijing Forestry University
2018-2022
Research Institute of Forestry
2018-2022
Chinese Academy of Forestry
2018-2022
State Forestry and Grassland Administration
2020-2022
China Animal Disease Control Center
2022
Xinyang College of Agriculture and Forestry
2022
China Academy of Railway Sciences
2021
Summary Overexpression of bacterial γ‐glutamylcysteine synthetase in the cytosol P opulus tremula × . alba produces higher glutathione ( GSH ) concentrations leaves, thereby indicating potential for cadmium C d) phytoremediation. However, net d 2+ influx association with H + / a , tolerance, and underlying molecular physiological mechanisms are uncharacterized these poplars. We assessed influx, tolerance transcriptional regulation several genes involved transport detoxification wild‐type...
Bark tissue of Populus × canescens can hyperaccumulate cadmium, but microstructural, transcriptomic, and physiological response mechanisms are poorly understood. Histochemical assays, transmission electron microscopic observations, energy-dispersive x-ray microanalysis, transcriptomic analyses have been performed to enhance our understanding cadmium accumulation detoxification in P. canescens. Cadmium was allocated the phloem bark, subcellular compartmentalization occurred mainly vacuoles...
Ectomycorrhizas ( EMs ), which are symbiotic organs formed between tree roots and certain fungi, can mediate cadmium Cd ) tolerance of host plants, but the underlying physiological molecular mechanisms not fully understood. P opulus × canescens was inoculated with or without axillus involutus (strain MAJ subsequently exposed to 0 50 μM CdSO 4 . Higher net 2+ influx in well corresponded higher transcript levels genes involved uptake, transport detoxification processes than those...
The gut microbial association with host co-existence is critical for body homeostasis and pathogenicity.Graves' disease (GD) an autoimmune manifested hyperthyroidism ophthalmopathy.However, we hypothesized that bacteria could affect important role in GD pathogenicity.The current study aim was to characterize investigate the intestinal bacterial composition of qualitatively quantitatively.27 11 healthy controls were enrolled fecal sample collection.The PCR-DGGE 16S rRNA gene by targeting V3...
Glutathione (GSH) plays an important role in cadmium (Cd) tolerance woody plants, but the underlying mechanisms remain largely unknown. To elucidate physiological and transcriptional regulation of GSH-mediated Cd we exposed Populus × canescens (Ait.) Smith saplings to either 0 or 75 μM together with one three external GSH levels. treatments include buthionine sulfoximine (BSO, inhibitor biosynthesis), no exogenous GSH. External resulted higher Cd2+ uptake rate roots, greater amount poplars,...
Hantavirus, a rodent-borne zoonotic pathogen, has global distribution with 200,000 human infections diagnosed annually. In recent decades, repeated outbreaks of hantavirus have been reported in Eurasia and America. These led to public concern an interest understanding the underlying biological mechanisms. Here, we propose climate-animal-Hantaan virus (HTNV) infection model address this issue, using unique dataset spanning 54-y period (1960-2013). This comes from Central China, focal point...
Abstract Cultivated chrysanthemum (Chrysanthemum × morifolium Ramat.) is a beloved ornamental crop due to the diverse capitula types among varieties, but molecular mechanism of capitulum development remains unclear. Here, we report 2.60 Gb chromosome-scale reference genome C. lavandulifolium, wild Chrysanthemum species found in China, Korea and Japan. The evolutionary analysis revealed that only recent tandem duplications occurred lavandulifolium after shared whole triplication (WGT)...
Zoonoses are increasingly recognized as an important burden on global public health in the 21st century. High-resolution, long-term field studies critical for assessing both baseline and future risk scenarios a world of rapid changes. We have used three-decade-long study hantavirus, rodent-borne zoonotic pathogen distributed worldwide, coupled with epidemiological data from endemic area China, show that shift ecological dynamics Hantaan virus was closely linked to environmental fluctuations...
Background Increased risks for hemorrhagic fever with renal syndrome (HFRS) caused by Hantaan virus have been observed since 2005, in Xi'an, China. Despite increased vigilance and preparedness, HFRS outbreaks 2010, 2011, 2012 were larger than ever, a total of 3,938 confirmed cases 88 deaths 2010 2011. Methods Findings Data on weather collected monthly from 2005 to 2012, along active rodent monitoring. Wavelet analyses performed assess the temporal relationship between incidence, density...
The outbreak of coronavirus disease 2019 (COVID-19) has spread across the world and was characterized as a pandemic. To protect medical laboratory personnel from infection, most laboratories inactivate virus causing COVID-19, severe acute respiratory syndrome 2 (SARS-CoV-2), in clinical samples before testing. However, effect inactivation on detection results remains unknown. Here, we used digital PCR assay to determine absolute SARS-CoV-2 RNA copy number 63 nasopharyngeal swab assess...
Outbreaks of ARD associated with HAdV have been reported in military populations many countries. Here, we report an outbreak caused by HAdV-7 a training camp Shaanxi Province, China, from February to March 2012. Epidemic data and samples the patients were collected, viral nucleotides isolations detected sequenced. IgG IgA antibodies against HAdV, neutralization strain isolated this outbreak, detected. Epidemiological study showed that all personnel affected males average age 19.1 years. Two...
To investigate the physiological responses of poplars to amino acids as sole nitrogen (N) sources, Populus × canescens (Ait.) Smith plants were supplied with one three fertilizers (NH4NO3, phenylalanine (Phe) or mixture NH4NO3 and Phe) in sand culture. A larger root system, decreased leaf size CO2 assimilation rate was observed Phe- versus NH4NO3-treated poplars. Consistently, a greater biomass shoot growth detected Phe-supplied Decreased enzymatic activities nitrate reductase (NR),...
To exam the role of miR-92a/KLF2/miR-483 in pathogenesis metabolic syndrome. In this study, serum healthy controls and patients with syndrome were collected to detect circulating level miR-92a miR-483. vitro cultured HUVECs, overexpression or suppression miR-92a, miR-483 KLF2 determine relationship among Ang II, ox-LDL, high glucose treatment used mimic HUVECs HepG2 cells treated Telmisartan, Atorvastatin, metformin, its target gene expression was detected. animal experiment, ob/ob mice...
Herein, a novel and simple electrospray (ES) printing technique was developed for the fabrication of ultrathin graphene layers with precisely controlled nanometer-scale thickness, where oxide (GO) electrosprayed on wafers subsequently chemically reduced into GO (rGO). Utilizing that technique, we prepared rGO in-plane field-effect transistor (GFET)-based biosensors coupled portable prototype measuring system point-of-care detection pathogens. We illustrate use such GFETs to detect COVID-19,...
Sperm cells are of unique elongated structure and function, the development which is tightly regulated by existing proteins posttranslational modifications (PTM) these proteins. Based on phylogenetic relationships various swine breeds, Yorkshire boar believed to be distinctly different from Duroc boar. The comprehensive differential proteomics phosphoproteomics profilings were performed spermatozoa both boars. By peptide PTM quantification followed statistical analyses, 167 differentially...
A study was conducted to investigate the circulation of HRSV subgroup B (HRSVB) in China recent years. HRSVB sequences from 365 samples collected 1991, 2004 and 2008-2014 China, together with 332 Chinese obtained GenBank were analyzed determine geographic yearly distribution HRSVB. Phylogenetic analysis revealed these clustered into 4 genotypes different frequencies: BA (83%), CB1 (11%), SAB (3.0%) GB3 (0.7%). Between 2005 2013, there a co-circulation non-BA China. Genotypes BA9 BA10 two...