- Gastric Cancer Management and Outcomes
- Abdominal Surgery and Complications
- Traditional Chinese Medicine Analysis
- Traditional Chinese Medicine Studies
- Healthcare and Venom Research
- Reconstructive Facial Surgery Techniques
- Kidney Stones and Urolithiasis Treatments
- Spine and Intervertebral Disc Pathology
- Anesthesia and Neurotoxicity Research
- Reconstructive Surgery and Microvascular Techniques
- Sleep and Wakefulness Research
- Pediatric Urology and Nephrology Studies
- Cerebrovascular and Carotid Artery Diseases
- Lung Cancer Treatments and Mutations
- Liver Disease Diagnosis and Treatment
- Neurological Disease Mechanisms and Treatments
- Metastasis and carcinoma case studies
- Medical Imaging and Analysis
- Hepatocellular Carcinoma Treatment and Prognosis
- Genomics and Phylogenetic Studies
- Sarcoma Diagnosis and Treatment
- Neuroscience and Neuropharmacology Research
- Parathyroid Disorders and Treatments
- Pancreatitis Pathology and Treatment
- Neuroinflammation and Neurodegeneration Mechanisms
Affiliated Hospital of North Sichuan Medical College
2007-2025
Chongqing Medical University
2009-2025
Zhengzhou University
2025
Kunming Medical University
2021-2025
Yan'an Hospital Affiliated To Kunming Medical University
2021-2025
Sichuan University
2025
General Hospital of Shenyang Military Region
2025
Third Affiliated Hospital of Zhengzhou University
2025
The Eighth Hospital of Xi'an
2025
Weatherford College
2024
Hydrogen peroxide (H2O2)-induced mitochondrial oxidative damage is critical to intestinal ischemia/reperfusion (I/R) injury, and PRDX3 an efficient H2O2 scavenger that protects cells from apoptosis. However, the function of in I/R injury unclear. The aim this study was investigate precise mechanism underlying involvement injury. An model established mice with superior mesenteric artery occlusion, Caco-2 were subjected hypoxia/reoxygenation (H/R) for vivo simulation I/R. expression decreased...
Supercritical fluid extraction (SFE) employing carbon dioxide (SC-CO
The Thermal Infrared Visual Object Tracking challenge 2015, VOT-TIR2015, aims at comparing short-term single-object visual trackers that work on thermal infrared (TIR) sequences and do not apply pre-learned models of object appearance. VOT-TIR2015 is the first benchmark tracking in TIR sequences. Results 24 are presented. For each participating tracker, a short description provided appendix. based VOT2013 challenge, but introduces following novelties: (i) newly collected LTIR (Link -- ping...
Somatic structural variations (Somatic SVs) are critical genomic alterations with significant implications in cancer genomics. Although long-read sequencing (LRS) theoretically provides optimal resolution for detecting these variants due to its ability span large segments, current LRS - based methods, which derived from short read somatic SV detection algorithms, mainly rely on split information. The high error rate of long and the errors introduced by seed-and-chaining strategy mainstream...
Malignant pleural effusion (MPE) is an indication of advanced cancer. Immune dysfunction often occurs in MPE. We aimed to identify the reason for impaired T cell activity MPE from lung cancer patients and provide clues toward potential immune therapies The surface inhibitory molecules cytotoxic cells peripheral blood (PB) were analyzed using flow cytometry. Levels inflammatory cytokines PB tested ELISA. TGF-β expression tumor-associated macrophages (TAMs) was also analyzed. effect TAMs on...
Background: Patients with ulcerative colitis (UC) usually display cognitive impairments, such as memory loss, attention deficits, and declining executive functions, particularly during the active stage of disease. However, potential neurological mechanisms these symptoms remain unclear. Method: Forty-one patients mildly to moderately UC, well 42 matched healthy controls, were recruited for an examination using psychological scales, function tests resting-state functional magnetic resonance...
We examined a novel farnesoid X receptor agonist, EDP‐305, for its antifibrotic effect in bile duct ligation (BDL) and choline‐deficient, L‐amino acid‐defined, high‐fat diet (CDAHFD) models of hepatic injury. used molecular magnetic resonance imaging with the type 1 collagen‐binding probe EP‐3533 oxidized collagen‐specific gadolinium hydrazide to noninvasively measure treatment response. BDL rats (n = 8 each group) were treated either low or high doses EDP‐305 starting on day 4 after imaged...
Abstract Objective Population ageing, as a hot issue in global development, increases the burden of medical resources society. This study aims to assess current spatiotemporal evolution and interaction between population ageing mainland China; evaluate matching level ageing; forecast future trends resources, indicator ageing-resources (IAR). Methods Data on (EPR) (NHI, NBHI, NHTP) were obtained from China Health Statistics Yearbook Statistical (2011–2020). We employed spatial autocorrelation...
Background: Muscle invasive bladder cancer (MIBC) has a poor prognosis even after radical cystectomy (RC). Postoperative survival stratification based on radiomics and deep learning algorithms may be useful for treatment decision-making follow-up management. This study was aimed to develop validate (DL) model preoperative CT predicting post-cystectomy overall in patients with MIBC. Methods: MIBC who underwent RC were retrospectively included from four centers, divided into the training,...
The TNM staging system is far from perfect in predicting the survival of individual cancer patients because only gross anatomy considered. rates who have same stage disease vary across a wide spectrum. This study aimed to develop nomogram that incorporates other clinicopathologic factors for overall (OS) non-metastatic nasopharyngeal carcinoma (NPC) after curative treatments. We retrospectively collected clinical data 1520 NPC were diagnosed histologically between November 2000 and September...
Abstract Background Inflammation can induce cognitive dysfunction in patients who undergo surgery. Previous studies have demonstrated that both acute peripheral inflammation and anaesthetic insults, especially isoflurane (ISO), are risk factors for memory impairment. Few currently investigating the role of ISO under peri-inflammatory conditions, it is difficult to predict whether aggravate inflammation-induced deficits. HDACs, which essential learning, participate deacetylation lysine...
Curcumin has antifragmentation, antivirus, anti‐infection, and antioxidation properties. been proven to prevent the peroxidation of sperm testis membranes, thus enhancing motility reducing abnormalities. This study aims explore role curcumin in improving hydrocortisone (HCT)‐induced Leydig cell injury by upregulating Nrf2 pathway. Thirty male rats were divided into three groups: control group (CG, n = 10), model (MG, treatment (CTG, 10). CG fed 2.5 mL/kg carboxymethyl cellulose as a blank...
This study investigated the relationship between rs4673 of nicotinamide adenine dinucleotide phosphate oxidase p22PHOX gene and blood pressure (BP) response to acute salt loading in a Chinese population diagnosed with essential hypertension. An test was performed using 2 L normal saline (NS) infused over 4 hours. BP heart rate were recorded immediately after NS infusion hourly for next 3 Data analysis chi-squared test, Student t multivariable regression. A total 159 patients analyzed,...
Abstract Objectives: The purpose of this study was to investigate the safety and clinical effectiveness endoscopic unilateral laminectomy with bilateral decompression (END-ULBD) in patients adjacent segment disease (ASD) after lumbar fusion. Methods: We conducted a retrospective collected data on 9 fusion who were hospitalized our hospital from January 2021 2022. All patients, aged 54 77 years, received Endo-ULBD treatment, an average age 59.2±3.6 years. ASD segments are L2/3 1, L3/4 5,...
Objective: Persistent high-risk human papillomavirus (HPV) infection causes precancerous cervical lesions with subsequent progression to cancer. HPV is very common in women of childbearing age, particularly early onset sexual activity. Treatments such as cold knife conization are usually used for age intraepithelial neoplasia 2+, which may cause delayed fertility, insufficiency, and other adverse pregnancy outcomes during pregnancies. Methods: Focused ultrasound (FUS) a non-ionizing,...