A5026941505- Advanced Radiotherapy Techniques
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Glioma Diagnosis and Treatment
- Lung Cancer Diagnosis and Treatment
- Radiation Therapy and Dosimetry
- Head and Neck Cancer Studies
- Oral Health Pathology and Treatment
- Spectroscopy Techniques in Biomedical and Chemical Research
- Nuclear reactor physics and engineering
- Ocular Oncology and Treatments
- Radiation Effects and Dosimetry
- Radiation Dose and Imaging
- Geophysical Methods and Applications
- Oral health in cancer treatment
- Effects of Radiation Exposure
- Head and Neck Surgical Oncology
- Meningioma and schwannoma management
- Corneal Surgery and Treatments
- Nuclear Issues and Defense
- Blood properties and coagulation
- Management of metastatic bone disease
- Protease and Inhibitor Mechanisms
- Hedgehog Signaling Pathway Studies
- Quality and Safety in Healthcare
Yeditepe University Hospital
2024
Istanbul Eye Hospital
2019-2024
Yeditepe University
2021
Health and Environmental Sciences Institute
2021
Kocaeli Üniversitesi
2019-2021
Anadolu University
2010-2018
University Medical Center Utrecht
2005
Selçuk University
1999
Radiation therapy is widely used as a treatment tool for malignancies. However, radiation-related complications are still unavoidable risks off-target cells. Little known about radiation therapy's possible effects on mechanical features of the cells such human red blood (RBCs). RBCs nucleus-free circulating that can deform without losing functionality in healthy conditions. Thus, to evaluate vitro plasma membrane cells, were selected primary test model. exposed clinically prescribed...
<b><i>Background:</i></b> We evaluated the efficacy, toxicity, and dose responses of re-irradiation with stereotactic body radiotherapy (SBRT) in patients recurrent non- small cell lung cancer (NSCLC) after previous irradiation. <b><i>Patients Methods:</i></b> 28 were included. Previous median radiation doses 54 66 Gy. The interval time between SBRT was 14 months. follow-up 9 months (range 3-93 months). To evaluate effectiveness SBRT, local...
AIM: The aim of this study is to offer survival following radiation therapy using intensity-modulated radiotherapy or volumetric arc with temozolomide in patients glioblastoma. MATERIALS AND METHODS: Ninety-two previously treated high-grade glioma (World Health Organization [WHO] grade IV) were studied Anadolu Medical Center, Department Radiation Oncology, between January 2006 and July 2015. diagnosis was established by pathology all cases. median age 59 years (range, 19–86 years). tumor...
Objective: To present our experience with placing endovascular coils in pulmonary arteries used as a fiducial marker for CyberKnife therapy and to describe the technical details complications of procedure.Materials Methods: Between June 2005 September 2013, 163 patients primary or secondary lung malignancies, referred placement stereotactic radiosurgery, were retrospectively reviewed.Fourteen (9 men, 5 women; mean age, 70 years) history pneumonectomy (n = 3), lobectomy 3) severe...
Registration of different imaging modalities such as CT, MRI, functional MRI (fMRI), positron (PET) and single photon (SPECT) emission tomography is used in many clinical applications. Determining the quality any automatic registration procedure has been a challenging part because no gold standard available to evaluate registration. In this note we present method, called 'multiple sub-volume registration' (MSR) for assessing consistency rigid This done by registering sub-images one data set...
<b><i>Aim:</i></b> The purpose of this study was to compare 6 treatment planning methods (5-beam coplanar intensity-modulated radiotherapy (IMRT), 7-beam IMRT, noncoplanar 2 full arc volumetric modulated therapy (VMAT), half partial VMAT, and VMAT) for high-grade gliomas with target volumes (PTVs) overlapping the optic pathway and/or brainstem. <b><i>Patients Methods:</i></b> 27 previously-treated patients were replanned...
On the elastic profiles of human teeth after radiotherapy for head and neck cancers, generation dental complications, which may bring several side effects preventing quality life, has not well clarified. Thus, we aimed to show applicability using 320 MHz Scanning Acoustic Microscopy (SAM) in evaluation tooth damage acoustically at micrometer level following radiation therapy, also determination safe dose limits impede severe damage.This prospective study was performed by SAM employed an...
Matrix metalloproteinases (MMPs) are thought to be involved in eye disease and may present tears. MMP activity was measured by gelatine zymography. Active gelatinase levels were determined a degradation ELISA. Potential MMP‐9 (gelatinase‐B) monomer enzyme elevated ( P < 0.001) keratoconjunctivitis comparison normal MMP‐9, dimer form, fluids from cases eyes. Significant increases bioactivities seen tears 0.01). Enzymes dogs with biologically active indicating that both the forms of...
Abstract Objective This study evaluates various craniospinal irradiation (CSI) techniques used in Turkish centers to understand their advantages, disadvantages and overall effectiveness, with a focus on enhancing dose distribution. Methods Anonymized CT scans of adult pediatric patients, alongside target volumes organ-at-risk (OAR) structures, were shared 25 local radiotherapy centers. They tasked develop optimal treatment plans delivering 36 Gy 20 fractions 95% PTV coverage, while...
Aim The correlation between the MLC QA (IBA Dosimetry, Germany) results of picket fence test created with intentional errors and patient's quality assurance (QA) evaluation was investigated to assess impact multileaf collimator (MLC) positioning error on patient QA. Materials methods fence, including error-free errors, defined in Bank In, Out, Both were analyzed using 15 plans consisting stereotactic radiosurgery (SRS), body radiotherapy (SBRT), conventionally fractionated...
Abstract The effectiveness of PET-CT (positron emission tomography–computed tomography) was investigated for staging target delineation compared with CT-MR (computed tomography–magnetic resonance) and early response intensity-modulated radiotherapy (IMRT). Gross tumour volume–clinical volume (GTV-CTV) differences between 14 nasopharyngeal carcinoma (NPC) patients were compared. Evaluation doses organs at risk (OARs) done by IMRT plans. Responses evaluated both sets. changed MR-based TNM...
Purpose: The prevalence of liver metastases is very high for patients whose primary diagnosis are colorectal, pancreas, lung, and breast cancer. Local control the disease may increase both quality life survival. aim this study to show feasibility, efficiency, low morbidity combined with a local probability in use robotic stereotactic body radiation therapy (rSBRT) treatment metastases. Methods Materials: A total 55 84 from different sites who underwent rSBRT our center between July 2006...
Radiogenic dental damage is a common and crucial problem in patients receiving radiotherapy for malignancies the head neck region. Unfortunately, little known about development of complications after radiation therapy on microstructure profiles human tooth. Therefore, we propose novel method which primary focus to investigate, vitro, direct influences di↵erent doses elastic properties enamel dentin tooth by Scanning Acoustic Microscopy (SAM) at microscale. We obtain two-dimensional (2D)...
The goal of this study was to compare six treatment planning methods (IMRTand VMAT) for high grade gliomas that had PTVs overlapping the optic pathway and/or brainstem. METHOD AND MATERIALS:27 previously treated patients were replanned with IMRT5,IMRT7,IMRT7-non, VMAT2f, VMAT2hand VMAT2h-non.For comparison study, it selected in three different localization (right, left and center sided tumors) tumor. PTVoptics PTVbrainstem limited a maximum dose limit equal 54Gy minimum 51Gy. A IMRT plans...
Purpose/Objective: We retrospectively analyzed our five years experience with patient-specific VMAT QA using the PTW seven29/Octavius system and reported institutional guidelines action limits for delivery.Materials Methods: Since June 2009, 1001 patients were treated Elekta technique at institution.Treatment plans re-grouped according to treatment disease sites: (1) 437 highmodulated complex treatments head-neck, rectal, endometrial, brain tumours other sites, all optimized Masterplan...